Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 19 12 13 14 15 16 17 18 19 20 21 22 NA

PPP1R14A (protein phosphatase 1 regulatory inhibitor subunit 14A)

Identity

Alias_namesPPP1INL
protein phosphatase 1
Alias_symbol (synonym)CPI-17
Other aliasCPI17
HGNC (Hugo) PPP1R14A
LocusID (NCBI) 94274
Atlas_Id 43828
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 38251237 and ends at 38256591 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PPP1R14A (19q13.2) / EIF4G1 (3q27.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP1R14A   14871
Cards
Entrez_Gene (NCBI)PPP1R14A  94274  protein phosphatase 1 regulatory inhibitor subunit 14A
AliasesCPI-17; CPI17; PPP1INL
GeneCards (Weizmann)PPP1R14A
Ensembl hg19 (Hinxton)ENSG00000167641 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167641 [Gene_View]  chr19:38251237-38256591 [Contig_View]  PPP1R14A [Vega]
ICGC DataPortalENSG00000167641
TCGA cBioPortalPPP1R14A
AceView (NCBI)PPP1R14A
Genatlas (Paris)PPP1R14A
WikiGenes94274
SOURCE (Princeton)PPP1R14A
Genetics Home Reference (NIH)PPP1R14A
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R14A  -     chr19:38251237-38256591 -  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R14A  -     19q13.2   [Description]    (hg19-Feb_2009)
EnsemblPPP1R14A - 19q13.2 [CytoView hg19]  PPP1R14A - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBIPPP1R14A [Mapview hg19]  PPP1R14A [Mapview hg38]
OMIM608153   
Gene and transcription
Genbank (Entrez)AB056508 AB056509 AF123763 AY050670 BC021089
RefSeq transcript (Entrez)NM_001243947 NM_033256
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP1R14A
Cluster EST : UnigeneHs.631569 [ NCBI ]
CGAP (NCI)Hs.631569
Alternative Splicing GalleryENSG00000167641
Gene ExpressionPPP1R14A [ NCBI-GEO ]   PPP1R14A [ EBI - ARRAY_EXPRESS ]   PPP1R14A [ SEEK ]   PPP1R14A [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R14A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)94274
GTEX Portal (Tissue expression)PPP1R14A
Human Protein AtlasENSG00000167641-PPP1R14A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96A00   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96A00  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96A00
Splice isoforms : SwissVarQ96A00
PhosPhoSitePlusQ96A00
Domains : Interpro (EBI)PP1_inhibitor   
Domain families : Pfam (Sanger)PP1_inhibitor (PF05361)   
Domain families : Pfam (NCBI)pfam05361   
Conserved Domain (NCBI)PPP1R14A
DMDM Disease mutations94274
Blocks (Seattle)PPP1R14A
SuperfamilyQ96A00
Human Protein Atlas [tissue]ENSG00000167641-PPP1R14A [tissue]
Peptide AtlasQ96A00
HPRD16291
IPIIPI00059135   IPI00045503   
Protein Interaction databases
DIP (DOE-UCLA)Q96A00
IntAct (EBI)Q96A00
FunCoupENSG00000167641
BioGRIDPPP1R14A
STRING (EMBL)PPP1R14A
ZODIACPPP1R14A
Ontologies - Pathways
QuickGOQ96A00
Ontology : AmiGOprotein phosphatase inhibitor activity  cytosol  cellular response to drug  regulation of phosphorylation  negative regulation of catalytic activity  
Ontology : EGO-EBIprotein phosphatase inhibitor activity  cytosol  cellular response to drug  regulation of phosphorylation  negative regulation of catalytic activity  
Pathways : KEGGVascular smooth muscle contraction   
NDEx NetworkPPP1R14A
Atlas of Cancer Signalling NetworkPPP1R14A
Wikipedia pathwaysPPP1R14A
Orthology - Evolution
OrthoDB94274
GeneTree (enSembl)ENSG00000167641
Phylogenetic Trees/Animal Genes : TreeFamPPP1R14A
HOVERGENQ96A00
HOGENOMQ96A00
Homologs : HomoloGenePPP1R14A
Homology/Alignments : Family Browser (UCSC)PPP1R14A
Gene fusions - Rearrangements
Fusion: Tumor Portal PPP1R14A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R14A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R14A
dbVarPPP1R14A
ClinVarPPP1R14A
1000_GenomesPPP1R14A 
Exome Variant ServerPPP1R14A
ExAC (Exome Aggregation Consortium)ENSG00000167641
GNOMAD BrowserENSG00000167641
Genetic variants : HAPMAP94274
Genomic Variants (DGV)PPP1R14A [DGVbeta]
DECIPHERPPP1R14A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R14A 
Mutations
ICGC Data PortalPPP1R14A 
TCGA Data PortalPPP1R14A 
Broad Tumor PortalPPP1R14A
OASIS PortalPPP1R14A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R14A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP1R14A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R14A
DgiDB (Drug Gene Interaction Database)PPP1R14A
DoCM (Curated mutations)PPP1R14A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R14A (select a term)
intoGenPPP1R14A
Cancer3DPPP1R14A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608153   
Orphanet
MedgenPPP1R14A
Genetic Testing Registry PPP1R14A
NextProtQ96A00 [Medical]
TSGene94274
GENETestsPPP1R14A
Target ValidationPPP1R14A
Huge Navigator PPP1R14A [HugePedia]
snp3D : Map Gene to Disease94274
BioCentury BCIQPPP1R14A
ClinGenPPP1R14A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD94274
Chemical/Pharm GKB GenePA33623
Clinical trialPPP1R14A
Miscellaneous
canSAR (ICR)PPP1R14A (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R14A
EVEXPPP1R14A
GoPubMedPPP1R14A
iHOPPPP1R14A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 13:06:12 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.