Identity
HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
CREP,MSSGM2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84919
MIM: 613257
HGNC: 14951
Ensembl: ENSG00000158615
Variants:
dbSNP: 84919
ClinVar: 84919
TCGA: ENSG00000158615
COSMIC: PPP1R15B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000158615 | ENST00000367188 | Q5SWA1 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38159565 | 2024 | Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B. | 1 |
| 38159565 | 2024 | Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B. | 1 |
| 36930084 | 2023 | An integrative pan-cancer analysis illustrating the key role of LRP11 in cervical cancer. | 2 |
| 38139150 | 2023 | The PPP1R15 Family of eIF2-alpha Phosphatase Targeting Subunits (GADD34 and CReP). | 3 |
| 36930084 | 2023 | An integrative pan-cancer analysis illustrating the key role of LRP11 in cervical cancer. | 2 |
| 38139150 | 2023 | The PPP1R15 Family of eIF2-alpha Phosphatase Targeting Subunits (GADD34 and CReP). | 3 |
| 34847777 | 2021 | Substrate recognition determinants of human eIF2α phosphatases. | 3 |
| 34847777 | 2021 | Substrate recognition determinants of human eIF2α phosphatases. | 3 |
| 29599191 | 2018 | AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation. | 14 |
| 29599191 | 2018 | AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation. | 14 |
| 25325377 | 2015 | CIP2A regulates cancer metabolism and CREB phosphorylation in non-small cell lung cancer. | 10 |
| 26159176 | 2015 | A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly. | 39 |
| 26307080 | 2015 | Homozygous mutation in the eukaryotic translation initiation factor 2alpha phosphatase gene, PPP1R15B, is associated with severe microcephaly, short stature and intellectual disability. | 24 |
| 25325377 | 2015 | CIP2A regulates cancer metabolism and CREB phosphorylation in non-small cell lung cancer. | 10 |
| 26159176 | 2015 | A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly. | 39 |
Citation
Dessen P
PPP1R15B (protein phosphatase 1 regulatory subunit 15B)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46951/ppp1r15b
