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PPP1R16A (protein phosphatase 1 regulatory subunit 16A)

Identity

Alias_namesprotein phosphatase 1, regulatory (inhibitor) subunit 16A
protein phosphatase 1, regulatory subunit 16A
Alias_symbol (synonym)MGC14333
MYPT3
Other alias
HGNC (Hugo) PPP1R16A
LocusID (NCBI) 84988
Atlas_Id 47095
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 144477982 and ends at 144502121 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DUSP5 (10q25.2) / PPP1R16A (8q24.3)PPP1R16A (8q24.3) / CLDN4 (7q11.23)PPP1R16A 8q24.3 / CLDN4 7q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP1R16A   14941
Cards
Entrez_Gene (NCBI)PPP1R16A  84988  protein phosphatase 1 regulatory subunit 16A
AliasesMYPT3
GeneCards (Weizmann)PPP1R16A
Ensembl hg19 (Hinxton)ENSG00000160972 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160972 [Gene_View]  chr8:144477982-144502121 [Contig_View]  PPP1R16A [Vega]
ICGC DataPortalENSG00000160972
TCGA cBioPortalPPP1R16A
AceView (NCBI)PPP1R16A
Genatlas (Paris)PPP1R16A
WikiGenes84988
SOURCE (Princeton)PPP1R16A
Genetics Home Reference (NIH)PPP1R16A
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R16A  -     chr8:144477982-144502121 +  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R16A  -     8q24.3   [Description]    (hg19-Feb_2009)
EnsemblPPP1R16A - 8q24.3 [CytoView hg19]  PPP1R16A - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBIPPP1R16A [Mapview hg19]  PPP1R16A [Mapview hg38]
OMIM609172   
Gene and transcription
Genbank (Entrez)AK090471 BC007854 BC049841 BC053506 BM761618
RefSeq transcript (Entrez)NM_001329442 NM_001329443 NM_001329444 NM_001329445 NM_032902
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP1R16A
Cluster EST : UnigeneHs.734856 [ NCBI ]
CGAP (NCI)Hs.734856
Alternative Splicing GalleryENSG00000160972
Gene ExpressionPPP1R16A [ NCBI-GEO ]   PPP1R16A [ EBI - ARRAY_EXPRESS ]   PPP1R16A [ SEEK ]   PPP1R16A [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R16A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84988
GTEX Portal (Tissue expression)PPP1R16A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96I34   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96I34  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96I34
Splice isoforms : SwissVarQ96I34
PhosPhoSitePlusQ96I34
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Pase-1_reg_su_16AB   
Domain families : Pfam (Sanger)Ank_2 (PF12796)   
Domain families : Pfam (NCBI)pfam12796   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)PPP1R16A
DMDM Disease mutations84988
Blocks (Seattle)PPP1R16A
SuperfamilyQ96I34
Human Protein AtlasENSG00000160972
Peptide AtlasQ96I34
HPRD16454
IPIIPI00063273   IPI00978426   IPI00979044   
Protein Interaction databases
DIP (DOE-UCLA)Q96I34
IntAct (EBI)Q96I34
FunCoupENSG00000160972
BioGRIDPPP1R16A
STRING (EMBL)PPP1R16A
ZODIACPPP1R16A
Ontologies - Pathways
QuickGOQ96I34
Ontology : AmiGOprotein binding  plasma membrane  protein phosphatase regulator activity  regulation of catalytic activity  
Ontology : EGO-EBIprotein binding  plasma membrane  protein phosphatase regulator activity  regulation of catalytic activity  
NDEx NetworkPPP1R16A
Atlas of Cancer Signalling NetworkPPP1R16A
Wikipedia pathwaysPPP1R16A
Orthology - Evolution
OrthoDB84988
GeneTree (enSembl)ENSG00000160972
Phylogenetic Trees/Animal Genes : TreeFamPPP1R16A
HOVERGENQ96I34
HOGENOMQ96I34
Homologs : HomoloGenePPP1R16A
Homology/Alignments : Family Browser (UCSC)PPP1R16A
Gene fusions - Rearrangements
Fusion : MitelmanPPP1R16A/CLDN4 [8q24.3/7q11.23]  
Fusion: TCGAPPP1R16A 8q24.3 CLDN4 7q11.23 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R16A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R16A
dbVarPPP1R16A
ClinVarPPP1R16A
1000_GenomesPPP1R16A 
Exome Variant ServerPPP1R16A
ExAC (Exome Aggregation Consortium)PPP1R16A (select the gene name)
Genetic variants : HAPMAP84988
Genomic Variants (DGV)PPP1R16A [DGVbeta]
DECIPHERPPP1R16A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R16A 
Mutations
ICGC Data PortalPPP1R16A 
TCGA Data PortalPPP1R16A 
Broad Tumor PortalPPP1R16A
OASIS PortalPPP1R16A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R16A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP1R16A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R16A
DgiDB (Drug Gene Interaction Database)PPP1R16A
DoCM (Curated mutations)PPP1R16A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R16A (select a term)
intoGenPPP1R16A
Cancer3DPPP1R16A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609172   
Orphanet
MedgenPPP1R16A
Genetic Testing Registry PPP1R16A
NextProtQ96I34 [Medical]
TSGene84988
GENETestsPPP1R16A
Huge Navigator PPP1R16A [HugePedia]
snp3D : Map Gene to Disease84988
BioCentury BCIQPPP1R16A
ClinGenPPP1R16A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84988
Chemical/Pharm GKB GenePA33634
Clinical trialPPP1R16A
Miscellaneous
canSAR (ICR)PPP1R16A (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R16A
EVEXPPP1R16A
GoPubMedPPP1R16A
iHOPPPP1R16A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:32:22 CEST 2017

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