Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PPP1R16B (protein phosphatase 1 regulatory subunit 16B)

Identity

Alias_namesprotein phosphatase 1, regulatory (inhibitor) subunit 16B
protein phosphatase 1, regulatory subunit 16B
Alias_symbol (synonym)KIAA0823
TIMAP
ANKRD4
Other alias
HGNC (Hugo) PPP1R16B
LocusID (NCBI) 26051
Atlas_Id 41809
Location 20q11.23  [Link to chromosome band 20q11]
Location_base_pair Starts at 38805693 and ends at 38923024 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PPP1R16B (20q11.23) / TTI1 (20q11.23)SH3RF3 (2q12.3) / PPP1R16B (20q11.23)PPP1R16B 20q11.23 / TTI1 20q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP1R16B   15850
Cards
Entrez_Gene (NCBI)PPP1R16B  26051  protein phosphatase 1 regulatory subunit 16B
AliasesANKRD4; TIMAP
GeneCards (Weizmann)PPP1R16B
Ensembl hg19 (Hinxton)ENSG00000101445 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101445 [Gene_View]  chr20:38805693-38923024 [Contig_View]  PPP1R16B [Vega]
ICGC DataPortalENSG00000101445
TCGA cBioPortalPPP1R16B
AceView (NCBI)PPP1R16B
Genatlas (Paris)PPP1R16B
WikiGenes26051
SOURCE (Princeton)PPP1R16B
Genetics Home Reference (NIH)PPP1R16B
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R16B  -     chr20:38805693-38923024 +  20q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R16B  -     20q11.23   [Description]    (hg19-Feb_2009)
EnsemblPPP1R16B - 20q11.23 [CytoView hg19]  PPP1R16B - 20q11.23 [CytoView hg38]
Mapping of homologs : NCBIPPP1R16B [Mapview hg19]  PPP1R16B [Mapview hg38]
OMIM613275   
Gene and transcription
Genbank (Entrez)AB020630 AB177855 AF362910 AK026900 AK311244
RefSeq transcript (Entrez)NM_001172735 NM_015568
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP1R16B
Cluster EST : UnigeneHs.45719 [ NCBI ]
CGAP (NCI)Hs.45719
Alternative Splicing GalleryENSG00000101445
Gene ExpressionPPP1R16B [ NCBI-GEO ]   PPP1R16B [ EBI - ARRAY_EXPRESS ]   PPP1R16B [ SEEK ]   PPP1R16B [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R16B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26051
GTEX Portal (Tissue expression)PPP1R16B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96T49   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96T49  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96T49
Splice isoforms : SwissVarQ96T49
PhosPhoSitePlusQ96T49
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Pase-1_reg_su_16AB   
Domain families : Pfam (Sanger)Ank_2 (PF12796)   
Domain families : Pfam (NCBI)pfam12796   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)PPP1R16B
DMDM Disease mutations26051
Blocks (Seattle)PPP1R16B
SuperfamilyQ96T49
Human Protein AtlasENSG00000101445
Peptide AtlasQ96T49
HPRD15168
IPIIPI00045904   IPI00479794   
Protein Interaction databases
DIP (DOE-UCLA)Q96T49
IntAct (EBI)Q96T49
FunCoupENSG00000101445
BioGRIDPPP1R16B
STRING (EMBL)PPP1R16B
ZODIACPPP1R16B
Ontologies - Pathways
QuickGOQ96T49
Ontology : AmiGOpositive regulation of endothelial cell proliferation  protein binding  nucleus  plasma membrane  regulation of phosphatidylinositol 3-kinase signaling  nuclear speck  protein phosphatase regulator activity  positive regulation of protein dephosphorylation  negative regulation of protein dephosphorylation  cell projection  perinuclear region of cytoplasm  regulation of catalytic activity  regulation of filopodium assembly  establishment of endothelial barrier  negative regulation of peptidyl-serine dephosphorylation  positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis  
Ontology : EGO-EBIpositive regulation of endothelial cell proliferation  protein binding  nucleus  plasma membrane  regulation of phosphatidylinositol 3-kinase signaling  nuclear speck  protein phosphatase regulator activity  positive regulation of protein dephosphorylation  negative regulation of protein dephosphorylation  cell projection  perinuclear region of cytoplasm  regulation of catalytic activity  regulation of filopodium assembly  establishment of endothelial barrier  negative regulation of peptidyl-serine dephosphorylation  positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis  
NDEx NetworkPPP1R16B
Atlas of Cancer Signalling NetworkPPP1R16B
Wikipedia pathwaysPPP1R16B
Orthology - Evolution
OrthoDB26051
GeneTree (enSembl)ENSG00000101445
Phylogenetic Trees/Animal Genes : TreeFamPPP1R16B
HOVERGENQ96T49
HOGENOMQ96T49
Homologs : HomoloGenePPP1R16B
Homology/Alignments : Family Browser (UCSC)PPP1R16B
Gene fusions - Rearrangements
Fusion : MitelmanPPP1R16B/TTI1 [20q11.23/20q11.23]  
Fusion: TCGAPPP1R16B 20q11.23 TTI1 20q11.23 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R16B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R16B
dbVarPPP1R16B
ClinVarPPP1R16B
1000_GenomesPPP1R16B 
Exome Variant ServerPPP1R16B
ExAC (Exome Aggregation Consortium)PPP1R16B (select the gene name)
Genetic variants : HAPMAP26051
Genomic Variants (DGV)PPP1R16B [DGVbeta]
DECIPHERPPP1R16B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R16B 
Mutations
ICGC Data PortalPPP1R16B 
TCGA Data PortalPPP1R16B 
Broad Tumor PortalPPP1R16B
OASIS PortalPPP1R16B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R16B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP1R16B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R16B
DgiDB (Drug Gene Interaction Database)PPP1R16B
DoCM (Curated mutations)PPP1R16B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R16B (select a term)
intoGenPPP1R16B
Cancer3DPPP1R16B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613275   
Orphanet
MedgenPPP1R16B
Genetic Testing Registry PPP1R16B
NextProtQ96T49 [Medical]
TSGene26051
GENETestsPPP1R16B
Target ValidationPPP1R16B
Huge Navigator PPP1R16B [HugePedia]
snp3D : Map Gene to Disease26051
BioCentury BCIQPPP1R16B
ClinGenPPP1R16B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26051
Chemical/Pharm GKB GenePA33635
Clinical trialPPP1R16B
Miscellaneous
canSAR (ICR)PPP1R16B (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R16B
EVEXPPP1R16B
GoPubMedPPP1R16B
iHOPPPP1R16B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:50:39 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.