Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PPP1R1A (protein phosphatase 1 regulatory inhibitor subunit 1A)

Identity

Alias_namesprotein phosphatase 1
Other aliasI1
IPP1
HGNC (Hugo) PPP1R1A
LocusID (NCBI) 5502
Atlas_Id 47409
Location 12q13.2  [Link to chromosome band 12q13]
Location_base_pair Starts at 54973024 and ends at 54982443 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP1R1A   9286
Cards
Entrez_Gene (NCBI)PPP1R1A  5502  protein phosphatase 1 regulatory inhibitor subunit 1A
AliasesI1; IPP1
GeneCards (Weizmann)PPP1R1A
Ensembl hg19 (Hinxton)ENSG00000135447 [Gene_View]  chr12:54973024-54982443 [Contig_View]  PPP1R1A [Vega]
Ensembl hg38 (Hinxton)ENSG00000135447 [Gene_View]  chr12:54973024-54982443 [Contig_View]  PPP1R1A [Vega]
ICGC DataPortalENSG00000135447
TCGA cBioPortalPPP1R1A
AceView (NCBI)PPP1R1A
Genatlas (Paris)PPP1R1A
WikiGenes5502
SOURCE (Princeton)PPP1R1A
Genetics Home Reference (NIH)PPP1R1A
Genomic and cartography
GoldenPath hg19 (UCSC)PPP1R1A  -     chr12:54973024-54982443 -  12q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PPP1R1A  -     12q13.2   [Description]    (hg38-Dec_2013)
EnsemblPPP1R1A - 12q13.2 [CytoView hg19]  PPP1R1A - 12q13.2 [CytoView hg38]
Mapping of homologs : NCBIPPP1R1A [Mapview hg19]  PPP1R1A [Mapview hg38]
OMIM613246   
Gene and transcription
Genbank (Entrez)AK123969 AY063766 BC022470 BM876308 BP211831
RefSeq transcript (Entrez)NM_006741
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)PPP1R1A
Cluster EST : UnigeneHs.505662 [ NCBI ]
CGAP (NCI)Hs.505662
Alternative Splicing GalleryENSG00000135447
Gene ExpressionPPP1R1A [ NCBI-GEO ]   PPP1R1A [ EBI - ARRAY_EXPRESS ]   PPP1R1A [ SEEK ]   PPP1R1A [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5502
GTEX Portal (Tissue expression)PPP1R1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13522   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13522  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13522
Splice isoforms : SwissVarQ13522
PhosPhoSitePlusQ13522
Domains : Interpro (EBI)PPI_1DARPP-32   
Domain families : Pfam (Sanger)DARPP-32 (PF05395)   
Domain families : Pfam (NCBI)pfam05395   
Conserved Domain (NCBI)PPP1R1A
DMDM Disease mutations5502
Blocks (Seattle)PPP1R1A
SuperfamilyQ13522
Human Protein AtlasENSG00000135447
Peptide AtlasQ13522
HPRD17893
IPIIPI00299014   IPI00446538   IPI01022357   IPI01022508   
Protein Interaction databases
DIP (DOE-UCLA)Q13522
IntAct (EBI)Q13522
FunCoupENSG00000135447
BioGRIDPPP1R1A
STRING (EMBL)PPP1R1A
ZODIACPPP1R1A
Ontologies - Pathways
QuickGOQ13522
Ontology : AmiGOprotein serine/threonine phosphatase inhibitor activity  protein binding  extracellular space  cytoplasm  glycogen metabolic process  negative regulation of protein kinase activity  intracellular signal transduction  
Ontology : EGO-EBIprotein serine/threonine phosphatase inhibitor activity  protein binding  extracellular space  cytoplasm  glycogen metabolic process  negative regulation of protein kinase activity  intracellular signal transduction  
Pathways : KEGGAdrenergic signaling in cardiomyocytes    Long-term potentiation   
NDEx NetworkPPP1R1A
Atlas of Cancer Signalling NetworkPPP1R1A
Wikipedia pathwaysPPP1R1A
Orthology - Evolution
OrthoDB5502
GeneTree (enSembl)ENSG00000135447
Phylogenetic Trees/Animal Genes : TreeFamPPP1R1A
HOVERGENQ13522
HOGENOMQ13522
Homologs : HomoloGenePPP1R1A
Homology/Alignments : Family Browser (UCSC)PPP1R1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R1A
dbVarPPP1R1A
ClinVarPPP1R1A
1000_GenomesPPP1R1A 
Exome Variant ServerPPP1R1A
ExAC (Exome Aggregation Consortium)PPP1R1A (select the gene name)
Genetic variants : HAPMAP5502
Genomic Variants (DGV)PPP1R1A [DGVbeta]
DECIPHER (Syndromes)12:54973024-54982443  ENSG00000135447
CONAN: Copy Number AnalysisPPP1R1A 
Mutations
ICGC Data PortalPPP1R1A 
TCGA Data PortalPPP1R1A 
Broad Tumor PortalPPP1R1A
OASIS PortalPPP1R1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP1R1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R1A
DgiDB (Drug Gene Interaction Database)PPP1R1A
DoCM (Curated mutations)PPP1R1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R1A (select a term)
intoGenPPP1R1A
Cancer3DPPP1R1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613246   
Orphanet
MedgenPPP1R1A
Genetic Testing Registry PPP1R1A
NextProtQ13522 [Medical]
TSGene5502
GENETestsPPP1R1A
Huge Navigator PPP1R1A [HugePedia]
snp3D : Map Gene to Disease5502
BioCentury BCIQPPP1R1A
ClinGenPPP1R1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5502
Chemical/Pharm GKB GenePA33636
Clinical trialPPP1R1A
Miscellaneous
canSAR (ICR)PPP1R1A (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R1A
EVEXPPP1R1A
GoPubMedPPP1R1A
iHOPPPP1R1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:22:32 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.