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PPP1R27 (protein phosphatase 1 regulatory subunit 27)

Identity

Alias_namesDYSFIP1
dysferlin-interacting protein 1 (toonin)
dysferlin interacting protein 1 (toonin)
dysferlin interacting protein 1
protein phosphatase 1, regulatory subunit 27
Alias_symbol (synonym)toonin
Other alias
HGNC (Hugo) PPP1R27
LocusID (NCBI) 116729
Atlas_Id 72146
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 81833492 and ends at 81835050 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP1R27   16813
Cards
Entrez_Gene (NCBI)PPP1R27  116729  protein phosphatase 1 regulatory subunit 27
AliasesDYSFIP1
GeneCards (Weizmann)PPP1R27
Ensembl hg19 (Hinxton)ENSG00000182676 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182676 [Gene_View]  chr17:81833492-81835050 [Contig_View]  PPP1R27 [Vega]
ICGC DataPortalENSG00000182676
TCGA cBioPortalPPP1R27
AceView (NCBI)PPP1R27
Genatlas (Paris)PPP1R27
WikiGenes116729
SOURCE (Princeton)PPP1R27
Genetics Home Reference (NIH)PPP1R27
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R27  -     chr17:81833492-81835050 -  17q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R27  -     17q25.3   [Description]    (hg19-Feb_2009)
EnsemblPPP1R27 - 17q25.3 [CytoView hg19]  PPP1R27 - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBIPPP1R27 [Mapview hg19]  PPP1R27 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA722724 AF434846 AK096888 BC093707 BC112094
RefSeq transcript (Entrez)NM_001007533
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP1R27
Cluster EST : UnigeneHs.454720 [ NCBI ]
CGAP (NCI)Hs.454720
Alternative Splicing GalleryENSG00000182676
Gene ExpressionPPP1R27 [ NCBI-GEO ]   PPP1R27 [ EBI - ARRAY_EXPRESS ]   PPP1R27 [ SEEK ]   PPP1R27 [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R27 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116729
GTEX Portal (Tissue expression)PPP1R27
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86WC6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86WC6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86WC6
Splice isoforms : SwissVarQ86WC6
PhosPhoSitePlusQ86WC6
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)PPP1R27
DMDM Disease mutations116729
Blocks (Seattle)PPP1R27
SuperfamilyQ86WC6
Human Protein AtlasENSG00000182676
Peptide AtlasQ86WC6
HPRD17334
IPIIPI00161379   
Protein Interaction databases
DIP (DOE-UCLA)Q86WC6
IntAct (EBI)Q86WC6
FunCoupENSG00000182676
BioGRIDPPP1R27
STRING (EMBL)PPP1R27
ZODIACPPP1R27
Ontologies - Pathways
QuickGOQ86WC6
Ontology : AmiGOprotein phosphatase inhibitor activity  protein binding  negative regulation of phosphatase activity  phosphatase binding  
Ontology : EGO-EBIprotein phosphatase inhibitor activity  protein binding  negative regulation of phosphatase activity  phosphatase binding  
NDEx NetworkPPP1R27
Atlas of Cancer Signalling NetworkPPP1R27
Wikipedia pathwaysPPP1R27
Orthology - Evolution
OrthoDB116729
GeneTree (enSembl)ENSG00000182676
Phylogenetic Trees/Animal Genes : TreeFamPPP1R27
HOVERGENQ86WC6
HOGENOMQ86WC6
Homologs : HomoloGenePPP1R27
Homology/Alignments : Family Browser (UCSC)PPP1R27
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R27 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R27
dbVarPPP1R27
ClinVarPPP1R27
1000_GenomesPPP1R27 
Exome Variant ServerPPP1R27
ExAC (Exome Aggregation Consortium)PPP1R27 (select the gene name)
Genetic variants : HAPMAP116729
Genomic Variants (DGV)PPP1R27 [DGVbeta]
DECIPHERPPP1R27 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R27 
Mutations
ICGC Data PortalPPP1R27 
TCGA Data PortalPPP1R27 
Broad Tumor PortalPPP1R27
OASIS PortalPPP1R27 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPPP1R27
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R27
DgiDB (Drug Gene Interaction Database)PPP1R27
DoCM (Curated mutations)PPP1R27 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R27 (select a term)
intoGenPPP1R27
Cancer3DPPP1R27(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPPP1R27
Genetic Testing Registry PPP1R27
NextProtQ86WC6 [Medical]
TSGene116729
GENETestsPPP1R27
Target ValidationPPP1R27
Huge Navigator PPP1R27 [HugePedia]
snp3D : Map Gene to Disease116729
BioCentury BCIQPPP1R27
ClinGenPPP1R27
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116729
Chemical/Pharm GKB GenePA27555
Clinical trialPPP1R27
Miscellaneous
canSAR (ICR)PPP1R27 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R27
EVEXPPP1R27
GoPubMedPPP1R27
iHOPPPP1R27
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:37:07 CEST 2017

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