Atlas of Genetics and Cytogenetics in Oncology and Haematology

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PPP1R3B (protein phosphatase 1 regulatory subunit 3B)

Identity

Alias_namesprotein phosphatase 1, regulatory (inhibitor) subunit 3B
protein phosphatase 1, regulatory subunit 3B
Alias_symbol (synonym)GL
FLJ14005
PPP1R4
Other aliasPTG
HGNC (Hugo) PPP1R3B
LocusID (NCBI) 79660
Atlas_Id 46909
Location 7q31.1  [Link to chromosome band 7q31]
Location_base_pair Starts at 9136254 and ends at 9150710 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PPP1R3B (8p23.1) / GATA2 (3q21.3)SNHG3 (1p35.3) / PPP1R3B (8p23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PPP1R3B   14942
Cards
Entrez_Gene (NCBI)PPP1R3B  79660  protein phosphatase 1 regulatory subunit 3B
AliasesGL; PPP1R4; PTG
GeneCards (Weizmann)PPP1R3B
Ensembl hg19 (Hinxton)ENSG00000173281 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173281 [Gene_View]  ENSG00000173281 [Sequence]  chr8:9136254-9150710 [Contig_View]  PPP1R3B [Vega]
ICGC DataPortalENSG00000173281
TCGA cBioPortalPPP1R3B
AceView (NCBI)PPP1R3B
Genatlas (Paris)PPP1R3B
WikiGenes79660
SOURCE (Princeton)PPP1R3B
Genetics Home Reference (NIH)PPP1R3B
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R3B  -     chr8:9136254-9150710 -  7q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R3B  -     7q31.1   [Description]    (hg19-Feb_2009)
EnsemblPPP1R3B - 7q31.1 [CytoView hg19]  PPP1R3B - 7q31.1 [CytoView hg38]
Mapping of homologs : NCBIPPP1R3B [Mapview hg19]  PPP1R3B [Mapview hg38]
OMIM610541   
Gene and transcription
Genbank (Entrez)AI078688 AI263711 AK024067 AK091994 AK096119
RefSeq transcript (Entrez)NM_001201329 NM_024607
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP1R3B
Cluster EST : UnigeneHs.458513 [ NCBI ]
CGAP (NCI)Hs.458513
Alternative Splicing GalleryENSG00000173281
Gene ExpressionPPP1R3B [ NCBI-GEO ]   PPP1R3B [ EBI - ARRAY_EXPRESS ]   PPP1R3B [ SEEK ]   PPP1R3B [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79660
GTEX Portal (Tissue expression)PPP1R3B
Human Protein AtlasENSG00000173281-PPP1R3B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86XI6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86XI6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86XI6
Splice isoforms : SwissVarQ86XI6
PhosPhoSitePlusQ86XI6
Domaine pattern : Prosite (Expaxy)CBM21 (PS51159)   
Domains : Interpro (EBI)CBM21_dom    CBM21_dom_sf    Pase-1_reg-su_3B/C/D_met    PP1_3B   
Domain families : Pfam (Sanger)CBM_21 (PF03370)   
Domain families : Pfam (NCBI)pfam03370   
Conserved Domain (NCBI)PPP1R3B
DMDM Disease mutations79660
Blocks (Seattle)PPP1R3B
PDB (SRS)2EEF   
PDB (PDBSum)2EEF   
PDB (IMB)2EEF   
PDB (RSDB)2EEF   
Structural Biology KnowledgeBase2EEF   
SCOP (Structural Classification of Proteins)2EEF   
CATH (Classification of proteins structures)2EEF   
SuperfamilyQ86XI6
Human Protein Atlas [tissue]ENSG00000173281-PPP1R3B [tissue]
Peptide AtlasQ86XI6
HPRD17894
IPIIPI00002415   
Protein Interaction databases
DIP (DOE-UCLA)Q86XI6
IntAct (EBI)Q86XI6
FunCoupENSG00000173281
BioGRIDPPP1R3B
STRING (EMBL)PPP1R3B
ZODIACPPP1R3B
Ontologies - Pathways
QuickGOQ86XI6
Ontology : AmiGOprotein phosphatase type 1 complex  phosphoprotein phosphatase activity  protein binding  glycogen metabolic process  regulation of glycogen biosynthetic process  regulation of glycogen catabolic process  protein dephosphorylation  protein phosphatase regulator activity  enzyme binding  glycogen granule  intracellular membrane-bounded organelle  regulation of phosphoprotein phosphatase activity  
Ontology : EGO-EBIprotein phosphatase type 1 complex  phosphoprotein phosphatase activity  protein binding  glycogen metabolic process  regulation of glycogen biosynthetic process  regulation of glycogen catabolic process  protein dephosphorylation  protein phosphatase regulator activity  enzyme binding  glycogen granule  intracellular membrane-bounded organelle  regulation of phosphoprotein phosphatase activity  
Pathways : KEGGInsulin signaling pathway   
NDEx NetworkPPP1R3B
Atlas of Cancer Signalling NetworkPPP1R3B
Wikipedia pathwaysPPP1R3B
Orthology - Evolution
OrthoDB79660
GeneTree (enSembl)ENSG00000173281
Phylogenetic Trees/Animal Genes : TreeFamPPP1R3B
HOVERGENQ86XI6
HOGENOMQ86XI6
Homologs : HomoloGenePPP1R3B
Homology/Alignments : Family Browser (UCSC)PPP1R3B
Gene fusions - Rearrangements
Fusion : QuiverPPP1R3B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R3B
dbVarPPP1R3B
ClinVarPPP1R3B
1000_GenomesPPP1R3B 
Exome Variant ServerPPP1R3B
ExAC (Exome Aggregation Consortium)ENSG00000173281
GNOMAD BrowserENSG00000173281
Varsome BrowserPPP1R3B
Genetic variants : HAPMAP79660
Genomic Variants (DGV)PPP1R3B [DGVbeta]
DECIPHERPPP1R3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R3B 
Mutations
ICGC Data PortalPPP1R3B 
TCGA Data PortalPPP1R3B 
Broad Tumor PortalPPP1R3B
OASIS PortalPPP1R3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP1R3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R3B
DgiDB (Drug Gene Interaction Database)PPP1R3B
DoCM (Curated mutations)PPP1R3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R3B (select a term)
intoGenPPP1R3B
Cancer3DPPP1R3B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610541   
Orphanet
DisGeNETPPP1R3B
MedgenPPP1R3B
Genetic Testing Registry PPP1R3B
NextProtQ86XI6 [Medical]
TSGene79660
GENETestsPPP1R3B
Target ValidationPPP1R3B
Huge Navigator PPP1R3B [HugePedia]
snp3D : Map Gene to Disease79660
BioCentury BCIQPPP1R3B
ClinGenPPP1R3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79660
Chemical/Pharm GKB GenePA33652
Clinical trialPPP1R3B
Miscellaneous
canSAR (ICR)PPP1R3B (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R3B
EVEXPPP1R3B
GoPubMedPPP1R3B
iHOPPPP1R3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 15:10:34 CEST 2018
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