Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PPP1R3C (protein phosphatase 1 regulatory subunit 3C)

Identity

Alias_namesPPP1R5
protein phosphatase 1, regulatory (inhibitor) subunit 3C
protein phosphatase 1, regulatory subunit 3C
Alias_symbol (synonym)PTG
Other alias
HGNC (Hugo) PPP1R3C
LocusID (NCBI) 5507
Atlas_Id 46712
Location 10q23.32  [Link to chromosome band 10q23]
Location_base_pair Starts at 91628441 and ends at 91633101 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP1R3C   9293
Cards
Entrez_Gene (NCBI)PPP1R3C  5507  protein phosphatase 1 regulatory subunit 3C
AliasesPPP1R5; PTG
GeneCards (Weizmann)PPP1R3C
Ensembl hg19 (Hinxton)ENSG00000119938 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119938 [Gene_View]  chr10:91628441-91633101 [Contig_View]  PPP1R3C [Vega]
ICGC DataPortalENSG00000119938
TCGA cBioPortalPPP1R3C
AceView (NCBI)PPP1R3C
Genatlas (Paris)PPP1R3C
WikiGenes5507
SOURCE (Princeton)PPP1R3C
Genetics Home Reference (NIH)PPP1R3C
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R3C  -     chr10:91628441-91633101 -  10q23.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R3C  -     10q23.32   [Description]    (hg19-Feb_2009)
EnsemblPPP1R3C - 10q23.32 [CytoView hg19]  PPP1R3C - 10q23.32 [CytoView hg38]
Mapping of homologs : NCBIPPP1R3C [Mapview hg19]  PPP1R3C [Mapview hg38]
OMIM602999   
Gene and transcription
Genbank (Entrez)AF087874 AI766011 AK299392 AK299398 AK313149
RefSeq transcript (Entrez)NM_005398
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP1R3C
Cluster EST : UnigeneHs.744999 [ NCBI ]
CGAP (NCI)Hs.744999
Alternative Splicing GalleryENSG00000119938
Gene ExpressionPPP1R3C [ NCBI-GEO ]   PPP1R3C [ EBI - ARRAY_EXPRESS ]   PPP1R3C [ SEEK ]   PPP1R3C [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R3C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5507
GTEX Portal (Tissue expression)PPP1R3C
Human Protein AtlasENSG00000119938-PPP1R3C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UQK1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UQK1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UQK1
Splice isoforms : SwissVarQ9UQK1
PhosPhoSitePlusQ9UQK1
Domaine pattern : Prosite (Expaxy)CBM21 (PS51159)   
Domains : Interpro (EBI)CBM21_dom    Pase-1_reg-su_3B/C/D_met    PP1_3C   
Domain families : Pfam (Sanger)CBM_21 (PF03370)   
Domain families : Pfam (NCBI)pfam03370   
Conserved Domain (NCBI)PPP1R3C
DMDM Disease mutations5507
Blocks (Seattle)PPP1R3C
SuperfamilyQ9UQK1
Human Protein Atlas [tissue]ENSG00000119938-PPP1R3C [tissue]
Peptide AtlasQ9UQK1
HPRD04298
IPIIPI00022523   IPI00911014   IPI01014545   IPI00382994   
Protein Interaction databases
DIP (DOE-UCLA)Q9UQK1
IntAct (EBI)Q9UQK1
FunCoupENSG00000119938
BioGRIDPPP1R3C
STRING (EMBL)PPP1R3C
ZODIACPPP1R3C
Ontologies - Pathways
QuickGOQ9UQK1
Ontology : AmiGOprotein serine/threonine phosphatase activity  protein binding  cytosol  glycogen metabolic process  glycogen biosynthetic process  glycogen biosynthetic process  protein dephosphorylation  protein phosphatase regulator activity  protein phosphatase binding  regulation of catalytic activity  
Ontology : EGO-EBIprotein serine/threonine phosphatase activity  protein binding  cytosol  glycogen metabolic process  glycogen biosynthetic process  glycogen biosynthetic process  protein dephosphorylation  protein phosphatase regulator activity  protein phosphatase binding  regulation of catalytic activity  
Pathways : KEGGInsulin signaling pathway   
NDEx NetworkPPP1R3C
Atlas of Cancer Signalling NetworkPPP1R3C
Wikipedia pathwaysPPP1R3C
Orthology - Evolution
OrthoDB5507
GeneTree (enSembl)ENSG00000119938
Phylogenetic Trees/Animal Genes : TreeFamPPP1R3C
HOVERGENQ9UQK1
HOGENOMQ9UQK1
Homologs : HomoloGenePPP1R3C
Homology/Alignments : Family Browser (UCSC)PPP1R3C
Gene fusions - Rearrangements
Tumor Fusion PortalPPP1R3C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R3C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R3C
dbVarPPP1R3C
ClinVarPPP1R3C
1000_GenomesPPP1R3C 
Exome Variant ServerPPP1R3C
ExAC (Exome Aggregation Consortium)ENSG00000119938
GNOMAD BrowserENSG00000119938
Genetic variants : HAPMAP5507
Genomic Variants (DGV)PPP1R3C [DGVbeta]
DECIPHERPPP1R3C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R3C 
Mutations
ICGC Data PortalPPP1R3C 
TCGA Data PortalPPP1R3C 
Broad Tumor PortalPPP1R3C
OASIS PortalPPP1R3C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R3C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP1R3C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R3C
DgiDB (Drug Gene Interaction Database)PPP1R3C
DoCM (Curated mutations)PPP1R3C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R3C (select a term)
intoGenPPP1R3C
Cancer3DPPP1R3C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602999   
Orphanet
DisGeNETPPP1R3C
MedgenPPP1R3C
Genetic Testing Registry PPP1R3C
NextProtQ9UQK1 [Medical]
TSGene5507
GENETestsPPP1R3C
Target ValidationPPP1R3C
Huge Navigator PPP1R3C [HugePedia]
snp3D : Map Gene to Disease5507
BioCentury BCIQPPP1R3C
ClinGenPPP1R3C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5507
Chemical/Pharm GKB GenePA33653
Clinical trialPPP1R3C
Miscellaneous
canSAR (ICR)PPP1R3C (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R3C
EVEXPPP1R3C
GoPubMedPPP1R3C
iHOPPPP1R3C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:29:57 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.