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PPP1R7 (protein phosphatase 1 regulatory subunit 7)

Identity

Alias_namesprotein phosphatase 1, regulatory (inhibitor) subunit 7
protein phosphatase 1, regulatory subunit 7
Alias_symbol (synonym)sds22
Other aliasSDS22
HGNC (Hugo) PPP1R7
LocusID (NCBI) 5510
Atlas_Id 47131
Location 2q37.3  [Link to chromosome band 2q37]
Location_base_pair Starts at 241149658 and ends at 241183650 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CD248 (11q13.2) / PPP1R7 (2q37.3)GIGYF2 (2q37.1) / PPP1R7 (2q37.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP1R7   9295
Cards
Entrez_Gene (NCBI)PPP1R7  5510  protein phosphatase 1 regulatory subunit 7
AliasesSDS22
GeneCards (Weizmann)PPP1R7
Ensembl hg19 (Hinxton)ENSG00000115685 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115685 [Gene_View]  chr2:241149658-241183650 [Contig_View]  PPP1R7 [Vega]
ICGC DataPortalENSG00000115685
TCGA cBioPortalPPP1R7
AceView (NCBI)PPP1R7
Genatlas (Paris)PPP1R7
WikiGenes5510
SOURCE (Princeton)PPP1R7
Genetics Home Reference (NIH)PPP1R7
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R7  -     chr2:241149658-241183650 +  2q37.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R7  -     2q37.3   [Description]    (hg19-Feb_2009)
EnsemblPPP1R7 - 2q37.3 [CytoView hg19]  PPP1R7 - 2q37.3 [CytoView hg38]
Mapping of homologs : NCBIPPP1R7 [Mapview hg19]  PPP1R7 [Mapview hg38]
OMIM602877   
Gene and transcription
Genbank (Entrez)AK294043 AK308015 BC000910 BC012397 BC013001
RefSeq transcript (Entrez)NM_001282409 NM_001282410 NM_001282411 NM_001282412 NM_001282413 NM_001282414 NM_002712
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP1R7
Cluster EST : UnigeneHs.36587 [ NCBI ]
CGAP (NCI)Hs.36587
Alternative Splicing GalleryENSG00000115685
Gene ExpressionPPP1R7 [ NCBI-GEO ]   PPP1R7 [ EBI - ARRAY_EXPRESS ]   PPP1R7 [ SEEK ]   PPP1R7 [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5510
GTEX Portal (Tissue expression)PPP1R7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15435   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15435  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15435
Splice isoforms : SwissVarQ15435
PhosPhoSitePlusQ15435
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    U2A'_phosphoprotein32A_C   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRcap (SM00446)  
Conserved Domain (NCBI)PPP1R7
DMDM Disease mutations5510
Blocks (Seattle)PPP1R7
SuperfamilyQ15435
Human Protein AtlasENSG00000115685
Peptide AtlasQ15435
HPRD04192
IPIIPI00033600   IPI00395771   IPI00759705   IPI00759816   IPI00894184   IPI00893943   IPI00893539   IPI00893774   IPI00893764   IPI00893379   IPI00893473   IPI00893238   
Protein Interaction databases
DIP (DOE-UCLA)Q15435
IntAct (EBI)Q15435
FunCoupENSG00000115685
BioGRIDPPP1R7
STRING (EMBL)PPP1R7
ZODIACPPP1R7
Ontologies - Pathways
QuickGOQ15435
Ontology : AmiGOprotein binding  nucleus  chromosome  cytoplasm  chromosome segregation  biological_process  protein phosphatase regulator activity  enzyme regulator activity  positive regulation of protein dephosphorylation  regulation of catalytic activity  extracellular exosome  
Ontology : EGO-EBIprotein binding  nucleus  chromosome  cytoplasm  chromosome segregation  biological_process  protein phosphatase regulator activity  enzyme regulator activity  positive regulation of protein dephosphorylation  regulation of catalytic activity  extracellular exosome  
NDEx NetworkPPP1R7
Atlas of Cancer Signalling NetworkPPP1R7
Wikipedia pathwaysPPP1R7
Orthology - Evolution
OrthoDB5510
GeneTree (enSembl)ENSG00000115685
Phylogenetic Trees/Animal Genes : TreeFamPPP1R7
HOVERGENQ15435
HOGENOMQ15435
Homologs : HomoloGenePPP1R7
Homology/Alignments : Family Browser (UCSC)PPP1R7
Gene fusions - Rearrangements
Fusion : MitelmanGIGYF2/PPP1R7 [2q37.1/2q37.3]  [t(2;2)(q37;q37)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R7
dbVarPPP1R7
ClinVarPPP1R7
1000_GenomesPPP1R7 
Exome Variant ServerPPP1R7
ExAC (Exome Aggregation Consortium)PPP1R7 (select the gene name)
Genetic variants : HAPMAP5510
Genomic Variants (DGV)PPP1R7 [DGVbeta]
DECIPHERPPP1R7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R7 
Mutations
ICGC Data PortalPPP1R7 
TCGA Data PortalPPP1R7 
Broad Tumor PortalPPP1R7
OASIS PortalPPP1R7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP1R7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R7
DgiDB (Drug Gene Interaction Database)PPP1R7
DoCM (Curated mutations)PPP1R7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R7 (select a term)
intoGenPPP1R7
Cancer3DPPP1R7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602877   
Orphanet
MedgenPPP1R7
Genetic Testing Registry PPP1R7
NextProtQ15435 [Medical]
TSGene5510
GENETestsPPP1R7
Huge Navigator PPP1R7 [HugePedia]
snp3D : Map Gene to Disease5510
BioCentury BCIQPPP1R7
ClinGenPPP1R7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5510
Chemical/Pharm GKB GenePA33658
Clinical trialPPP1R7
Miscellaneous
canSAR (ICR)PPP1R7 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R7
EVEXPPP1R7
GoPubMedPPP1R7
iHOPPPP1R7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:32:25 CEST 2017

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