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PPP1R9A (protein phosphatase 1 regulatory subunit 9A)

Identity

Alias (NCBI)NRB1
NRBI
Neurabin-I
HGNC (Hugo) PPP1R9A
HGNC Alias symbNeurabin-I
KIAA1222
FLJ20068
HGNC Previous nameprotein phosphatase 1, regulatory (inhibitor) subunit 9A
 protein phosphatase 1, regulatory subunit 9A
LocusID (NCBI) 55607
Atlas_Id 41812
Location 7q21.3  [Link to chromosome band 7q21]
Location_base_pair Starts at 94907637 and ends at 95296421 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PPP1R9A (7q21.3)::MDM4 (1q32.1)PPP1R9A (7q21.3)::PPP1R9A (7q21.3)PPP1R9A (7q21.3)::XRCC2 (7q36.1)
WBSCR17 (7q11.22)::PPP1R9A (7q21.3)WBSCR17 7q11.22::PPP1R9A 7q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  i(7)(q10)


External links

 

Nomenclature
HGNC (Hugo)PPP1R9A   14946
Cards
Entrez_Gene (NCBI)PPP1R9A    protein phosphatase 1 regulatory subunit 9A
AliasesNRB1; NRBI; Neurabin-I
GeneCards (Weizmann)PPP1R9A
Ensembl hg19 (Hinxton)ENSG00000158528 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158528 [Gene_View]  ENSG00000158528 [Sequence]  chr7:94907637-95296421 [Contig_View]  PPP1R9A [Vega]
ICGC DataPortalENSG00000158528
TCGA cBioPortalPPP1R9A
AceView (NCBI)PPP1R9A
Genatlas (Paris)PPP1R9A
SOURCE (Princeton)PPP1R9A
Genetics Home Reference (NIH)PPP1R9A
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R9A  -     chr7:94907637-95296421 +  7q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R9A  -     7q21.3   [Description]    (hg19-Feb_2009)
GoldenPathPPP1R9A - 7q21.3 [CytoView hg19]  PPP1R9A - 7q21.3 [CytoView hg38]
ImmunoBaseENSG00000158528
Genome Data Viewer NCBIPPP1R9A [Mapview hg19]  
OMIM602468   
Gene and transcription
Genbank (Entrez)AB033048 AK000075 AK096514 AK225204 BC037849
RefSeq transcript (Entrez)NM_001166160 NM_001166161 NM_001166162 NM_001166163 NM_017650
Consensus coding sequences : CCDS (NCBI)PPP1R9A
Gene ExpressionPPP1R9A [ NCBI-GEO ]   PPP1R9A [ EBI - ARRAY_EXPRESS ]   PPP1R9A [ SEEK ]   PPP1R9A [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R9A [ Firebrowse - Broad ]
GenevisibleExpression of PPP1R9A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55607
GTEX Portal (Tissue expression)PPP1R9A
Human Protein AtlasENSG00000158528-PPP1R9A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULJ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULJ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULJ8
PhosPhoSitePlusQ9ULJ8
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)    SAM_DOMAIN (PS50105)   
Domains : Interpro (EBI)Neurabin-1    Neurabin-1/2_PDZ    Neurabin-like    PDZ    PDZ_sf    SAM    SAM/pointed_sf   
Domain families : Pfam (Sanger)PDZ (PF00595)    PDZ_5 (PF17817)    SAM_2 (PF07647)   
Domain families : Pfam (NCBI)pfam00595    pfam17817    pfam07647   
Domain families : Smart (EMBL)PDZ (SM00228)  SAM (SM00454)  
Conserved Domain (NCBI)PPP1R9A
PDB (RSDB)1WF8   
PDB Europe1WF8   
PDB (PDBSum)1WF8   
PDB (IMB)1WF8   
Structural Biology KnowledgeBase1WF8   
SCOP (Structural Classification of Proteins)1WF8   
CATH (Classification of proteins structures)1WF8   
SuperfamilyQ9ULJ8
AlphaFold pdb e-kbQ9ULJ8   
Human Protein Atlas [tissue]ENSG00000158528-PPP1R9A [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9ULJ8
IntAct (EBI)Q9ULJ8
BioGRIDPPP1R9A
STRING (EMBL)PPP1R9A
ZODIACPPP1R9A
Ontologies - Pathways
QuickGOQ9ULJ8
Ontology : AmiGOprotein binding  cytoplasm  actin filament organization  postsynaptic density  actin cytoskeleton  calcium-mediated signaling  filopodium  dendrite  cortical actin cytoskeleton  neuron projection development  dendritic spine  modulation of chemical synaptic transmission  actin filament binding  
Ontology : EGO-EBIprotein binding  cytoplasm  actin filament organization  postsynaptic density  actin cytoskeleton  calcium-mediated signaling  filopodium  dendrite  cortical actin cytoskeleton  neuron projection development  dendritic spine  modulation of chemical synaptic transmission  actin filament binding  
NDEx NetworkPPP1R9A
Atlas of Cancer Signalling NetworkPPP1R9A
Wikipedia pathwaysPPP1R9A
Orthology - Evolution
OrthoDB55607
GeneTree (enSembl)ENSG00000158528
Phylogenetic Trees/Animal Genes : TreeFamPPP1R9A
Homologs : HomoloGenePPP1R9A
Homology/Alignments : Family Browser (UCSC)PPP1R9A
Gene fusions - Rearrangements
Fusion : MitelmanWBSCR17::PPP1R9A [7q11.22/7q21.3]  
Fusion : QuiverPPP1R9A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R9A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R9A
dbVarPPP1R9A
ClinVarPPP1R9A
MonarchPPP1R9A
1000_GenomesPPP1R9A 
Exome Variant ServerPPP1R9A
GNOMAD BrowserENSG00000158528
Varsome BrowserPPP1R9A
ACMGPPP1R9A variants
VarityQ9ULJ8
Genomic Variants (DGV)PPP1R9A [DGVbeta]
DECIPHERPPP1R9A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R9A 
Mutations
ICGC Data PortalPPP1R9A 
TCGA Data PortalPPP1R9A 
Broad Tumor PortalPPP1R9A
OASIS PortalPPP1R9A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R9A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPPP1R9A
Mutations and Diseases : HGMDPPP1R9A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPPP1R9A
DgiDB (Drug Gene Interaction Database)PPP1R9A
DoCM (Curated mutations)PPP1R9A
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R9A
Cancer3DPPP1R9A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602468   
Orphanet
DisGeNETPPP1R9A
MedgenPPP1R9A
Genetic Testing Registry PPP1R9A
NextProtQ9ULJ8 [Medical]
GENETestsPPP1R9A
Target ValidationPPP1R9A
Huge Navigator PPP1R9A [HugePedia]
ClinGenPPP1R9A (curated)
Clinical trials, drugs, therapy
MyCancerGenomePPP1R9A
Protein Interactions : CTDPPP1R9A
Pharm GKB GenePA33661
PharosQ9ULJ8
Clinical trialPPP1R9A
Miscellaneous
canSAR (ICR)PPP1R9A
HarmonizomePPP1R9A
ARCHS4PPP1R9A
DataMed IndexPPP1R9A
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPPP1R9A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jan 20 12:53:30 CET 2022

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