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PPP2R2D (protein phosphatase 2 regulatory subunit B, delta)

Identity

Alias_namesprotein phosphatase 2
Alias_symbol (synonym)MDS026
Other alias
HGNC (Hugo) PPP2R2D
LocusID (NCBI) 55844
Atlas_Id 47466
Location 10q26.3  [Link to chromosome band 10q26]
Location_base_pair Starts at 133747955 and ends at 133773338 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PPP2R2D (10q26.3) / CPNE2 (16q13)PPP2R2D (10q26.3) / PPP2R2D (10q26.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP2R2D   23732
Cards
Entrez_Gene (NCBI)PPP2R2D  55844  protein phosphatase 2 regulatory subunit B, delta
AliasesMDS026
GeneCards (Weizmann)PPP2R2D
Ensembl hg19 (Hinxton)ENSG00000175470 [Gene_View]  chr10:133747955-133773338 [Contig_View]  PPP2R2D [Vega]
Ensembl hg38 (Hinxton)ENSG00000175470 [Gene_View]  chr10:133747955-133773338 [Contig_View]  PPP2R2D [Vega]
ICGC DataPortalENSG00000175470
TCGA cBioPortalPPP2R2D
AceView (NCBI)PPP2R2D
Genatlas (Paris)PPP2R2D
WikiGenes55844
SOURCE (Princeton)PPP2R2D
Genetics Home Reference (NIH)PPP2R2D
Genomic and cartography
GoldenPath hg19 (UCSC)PPP2R2D  -     chr10:133747955-133773338 +  10q26.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PPP2R2D  -     10q26.3   [Description]    (hg38-Dec_2013)
EnsemblPPP2R2D - 10q26.3 [CytoView hg19]  PPP2R2D - 10q26.3 [CytoView hg38]
Mapping of homologs : NCBIPPP2R2D [Mapview hg19]  PPP2R2D [Mapview hg38]
OMIM613992   
Gene and transcription
Genbank (Entrez)AB040974 AF220046 AI521071 AK000402 AK001483
RefSeq transcript (Entrez)NM_001003656 NM_001291310 NM_018461
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_030059 NW_004929377
Consensus coding sequences : CCDS (NCBI)PPP2R2D
Cluster EST : UnigeneHs.657480 [ NCBI ]
CGAP (NCI)Hs.657480
Alternative Splicing GalleryENSG00000175470
Gene ExpressionPPP2R2D [ NCBI-GEO ]   PPP2R2D [ EBI - ARRAY_EXPRESS ]   PPP2R2D [ SEEK ]   PPP2R2D [ MEM ]
Gene Expression Viewer (FireBrowse)PPP2R2D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55844
GTEX Portal (Tissue expression)PPP2R2D
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ66LE6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ66LE6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ66LE6
Splice isoforms : SwissVarQ66LE6
PhosPhoSitePlusQ66LE6
Domaine pattern : Prosite (Expaxy)PR55_1 (PS01024)    PR55_2 (PS01025)   
Domains : Interpro (EBI)PP2A_PR55    PP2A_PR55_CS    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)PPP2R2D
DMDM Disease mutations55844
Blocks (Seattle)PPP2R2D
SuperfamilyQ66LE6
Human Protein AtlasENSG00000175470
Peptide AtlasQ66LE6
HPRD15172
IPIIPI00470920   IPI00984086   IPI00979177   
Protein Interaction databases
DIP (DOE-UCLA)Q66LE6
IntAct (EBI)Q66LE6
FunCoupENSG00000175470
BioGRIDPPP2R2D
STRING (EMBL)PPP2R2D
ZODIACPPP2R2D
Ontologies - Pathways
QuickGOQ66LE6
Ontology : AmiGOprotein phosphatase type 2A complex  cytoplasm  mitotic nuclear division  protein phosphatase type 2A regulator activity  exit from mitosis  regulation of protein phosphatase type 2A activity  regulation of protein phosphatase type 2A activity  cell division  
Ontology : EGO-EBIprotein phosphatase type 2A complex  cytoplasm  mitotic nuclear division  protein phosphatase type 2A regulator activity  exit from mitosis  regulation of protein phosphatase type 2A activity  regulation of protein phosphatase type 2A activity  cell division  
Pathways : KEGGmRNA surveillance pathway    PI3K-Akt signaling pathway    Adrenergic signaling in cardiomyocytes    Hippo signaling pathway    Tight junction    Dopaminergic synapse    Chagas disease (American trypanosomiasis)    Hepatitis C   
NDEx NetworkPPP2R2D
Atlas of Cancer Signalling NetworkPPP2R2D
Wikipedia pathwaysPPP2R2D
Orthology - Evolution
OrthoDB55844
GeneTree (enSembl)ENSG00000175470
Phylogenetic Trees/Animal Genes : TreeFamPPP2R2D
HOVERGENQ66LE6
HOGENOMQ66LE6
Homologs : HomoloGenePPP2R2D
Homology/Alignments : Family Browser (UCSC)PPP2R2D
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP2R2D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP2R2D
dbVarPPP2R2D
ClinVarPPP2R2D
1000_GenomesPPP2R2D 
Exome Variant ServerPPP2R2D
ExAC (Exome Aggregation Consortium)PPP2R2D (select the gene name)
Genetic variants : HAPMAP55844
Genomic Variants (DGV)PPP2R2D [DGVbeta]
DECIPHER (Syndromes)10:133747955-133773338  ENSG00000175470
CONAN: Copy Number AnalysisPPP2R2D 
Mutations
ICGC Data PortalPPP2R2D 
TCGA Data PortalPPP2R2D 
Broad Tumor PortalPPP2R2D
OASIS PortalPPP2R2D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP2R2D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP2R2D
BioMutasearch PPP2R2D
DgiDB (Drug Gene Interaction Database)PPP2R2D
DoCM (Curated mutations)PPP2R2D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP2R2D (select a term)
intoGenPPP2R2D
Cancer3DPPP2R2D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613992   
Orphanet
MedgenPPP2R2D
Genetic Testing Registry PPP2R2D
NextProtQ66LE6 [Medical]
TSGene55844
GENETestsPPP2R2D
Huge Navigator PPP2R2D [HugePedia]
snp3D : Map Gene to Disease55844
BioCentury BCIQPPP2R2D
ClinGenPPP2R2D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55844
Chemical/Pharm GKB GenePA134899040
Clinical trialPPP2R2D
Miscellaneous
canSAR (ICR)PPP2R2D (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP2R2D
EVEXPPP2R2D
GoPubMedPPP2R2D
iHOPPPP2R2D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:15:22 CEST 2017

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