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PPP2R3A (protein phosphatase 2, regulatory subunit B'', alpha)

Identity

Other namesPPP2R3
PR130
PR72
HGNC (Hugo) PPP2R3A
LocusID (NCBI) 5523
Location 3q22.2
Location_base_pair Starts at 135684515 and ends at 135866752 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PPP2R3A   9307
Entrez_Gene (NCBI)PPP2R3A  5523  protein phosphatase 2, regulatory subunit B'', alpha
Cards
GeneCards (Weizmann)PPP2R3A
Ensembl (Hinxton)ENSG00000073711 [Gene_View]  chr3:135684515-135866752 [Contig_View]  PPP2R3A [Vega]
AceView (NCBI)PPP2R3A
Genatlas (Paris)PPP2R3A
SOURCE (Stanford)NM_001190447 NM_002718 NM_181897
Genomic and cartography
GoldenPath (UCSC)PPP2R3A  -  3q22.2   chr3:135684515-135866752 +  3q22.2   [Description]    (hg19-Feb_2009)
EnsemblPPP2R3A - 3q22.2 [CytoView]
Mapping of homologs : NCBIPPP2R3A [Mapview]
OMIM604944   
Gene and transcription
Genbank (Entrez)AK293012 AK298059 AK299544 AK302163 AK314243
RefSeq transcript (SRS)NM_001190447 NM_002718 NM_181897
RefSeq transcript (Entrez)NM_001190447 NM_002718 NM_181897
RefSeq genomic (SRS)AC_000135 NC_000003 NC_018914 NG_029234 NT_005612 NW_001838884 NW_004078013
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_029234 NT_005612 NW_001838884 NW_004078013
Consensus coding sequences : CCDS (NCBI)PPP2R3A
Cluster EST : UnigeneHs.518155 [ SRS ] Hs.518155 [ NCBI ]
CGAP (NCI)Hs.518155
Alternative Splicing : Fast-db (Paris)GSHG0021177
Alternative Splicing GalleryENSG00000073711
Gene ExpressionPPP2R3A [ NCBI-GEO ]   PPP2R3A [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ06190 (SRS) Q06190 (Uniprot)
NextProtQ06190
With graphics : InterProQ06190
Splice isoforms : SwissVarQ06190(Swissvar)
Domaine pattern : Prosite (SRS)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (SRS)EF-hand-like_dom    EF_Hand_1_Ca_BS    EF_HAND_2   
Domains : Interpro (EBI)EF-hand-like_dom    EF_Hand_1_Ca_BS    EF_HAND_2   
Related proteins : CluSTrQ06190
Domain families : Pfam (SRS)
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM5523
Blocks (Seattle)Q06190
Human Protein AtlasENSG00000073711
HPRD09225
IPIIPI00029144   IPI00218930   IPI00909020   IPI00944998   
Protein Interaction databases
DIP (DOE-UCLA)Q06190
IntAct (EBI)Q06190
FunCoupENSG00000073711
REACTOMEPPP2R3A
Protein Interaction Database5523
BioGRIDPPP2R3A
InParanoidQ06190
Interologous Interaction database Q06190
IntegromeDBPPP2R3A
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PPP2R3A
SNP (GeneSNP Utah)PPP2R3A
SNP : HGBasePPP2R3A
Genetic variants : HAPMAPPPP2R3A
Somatic Mutations in Cancer : COSMICPPP2R3A 
CONAN: Copy Number AnalysisPPP2R3A 
Mutations and Diseases : HGMDPPP2R3A
OMIM604944   
GENETests604944   
Disease Genetic AssociationPPP2R3A
Huge Navigator PPP2R3A [HugePedia]  PPP2R3A [HugeCancerGEM]
Genomic VariantsPPP2R3A  PPP2R3A [DGVbeta]
snp3D : Map Gene to Disease5523
General knowledge
Homologs : HomoloGenePPP2R3A
Homology/Alignments : Family Browser (UCSC)PPP2R3A
Phylogenetic Trees/Animal Genes : TreeFamPPP2R3A
Chemical/Protein Interactions : CTD5523
Chemical/Pharm GKB GenePA35523
Clinical trialPPP2R3A
Cancer Resource (Charite)ENSG00000073711
Ontology : AmiGOprotein phosphatase type 2A complex  protein phosphatase type 2A complex  protein phosphatase type 2A complex  eye photoreceptor cell differentiation  calcium ion binding  protein binding  protein dephosphorylation  somatic muscle development  protein phosphatase type 2A regulator activity  positive regulation of protein catabolic process  somite development  negative regulation of canonical Wnt receptor signaling pathway  Wnt receptor signaling pathway involved in somitogenesis  regulation of cell motility involved in somitogenic axis elongation  positive regulation of canonical Wnt receptor signaling pathway  
Ontology : EGO-EBIprotein phosphatase type 2A complex  protein phosphatase type 2A complex  protein phosphatase type 2A complex  eye photoreceptor cell differentiation  calcium ion binding  protein binding  protein dephosphorylation  somatic muscle development  protein phosphatase type 2A regulator activity  positive regulation of protein catabolic process  somite development  negative regulation of canonical Wnt receptor signaling pathway  Wnt receptor signaling pathway involved in somitogenesis  regulation of cell motility involved in somitogenic axis elongation  positive regulation of canonical Wnt receptor signaling pathway  
Pathways : KEGGTight junction
Other databases
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
PubGenePPP2R3A
iHOPPPP2R3A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:36:15 CEST 2013
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