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PPP2R3B (protein phosphatase 2 regulatory subunit B''beta)

Identity

Alias_namesPPP2R3L
protein phosphatase 2 (formerly 2A)
Alias_symbol (synonym)PPP2R3LY
PR48
Other aliasNYREN8
PR70
HGNC (Hugo) PPP2R3B
LocusID (NCBI) 28227
Atlas_Id 43815
Location Xp22.33  [Link to chromosome band Xp22]
Location_base_pair Starts at 333933 and ends at 386955 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DNAJC4 (11q13.1) / PPP2R3B (Xp22.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP2R3B   13417
Cards
Entrez_Gene (NCBI)PPP2R3B  28227  protein phosphatase 2 regulatory subunit B''beta
AliasesNYREN8; PPP2R3L; PPP2R3LY; PR48; 
PR70
GeneCards (Weizmann)PPP2R3B
Ensembl hg19 (Hinxton)ENSG00000167393 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167393 [Gene_View]  chrX:333933-386955 [Contig_View]  PPP2R3B [Vega]
ICGC DataPortalENSG00000167393
TCGA cBioPortalPPP2R3B
AceView (NCBI)PPP2R3B
Genatlas (Paris)PPP2R3B
WikiGenes28227
SOURCE (Princeton)PPP2R3B
Genetics Home Reference (NIH)PPP2R3B
Genomic and cartography
GoldenPath hg38 (UCSC)PPP2R3B  -     chrX:333933-386955 -  Xp22.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP2R3B  -     Xp22.33   [Description]    (hg19-Feb_2009)
EnsemblPPP2R3B - Xp22.33 [CytoView hg19]  PPP2R3B - Xp22.33 [CytoView hg38]
Mapping of homologs : NCBIPPP2R3B [Mapview hg19]  PPP2R3B [Mapview hg38]
OMIM300339   
Gene and transcription
Genbank (Entrez)AB209137 AF135016 AF155098 AI248426 AK293506
RefSeq transcript (Entrez)NM_013239 NM_199326
RefSeq genomic (Entrez)NC_000023 NC_000024 NC_018934 NG_013257 NT_187634 NT_187667
Consensus coding sequences : CCDS (NCBI)PPP2R3B
Cluster EST : UnigeneHs.124942 [ NCBI ]
CGAP (NCI)Hs.124942
Alternative Splicing GalleryENSG00000167393
Gene ExpressionPPP2R3B [ NCBI-GEO ]   PPP2R3B [ EBI - ARRAY_EXPRESS ]   PPP2R3B [ SEEK ]   PPP2R3B [ MEM ]
Gene Expression Viewer (FireBrowse)PPP2R3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28227
GTEX Portal (Tissue expression)PPP2R3B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5P8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5P8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5P8
Splice isoforms : SwissVarQ9Y5P8
PhosPhoSitePlusQ9Y5P8
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam13499   
Conserved Domain (NCBI)PPP2R3B
DMDM Disease mutations28227
Blocks (Seattle)PPP2R3B
PDB (SRS)4I5L    4I5N    4MEW   
PDB (PDBSum)4I5L    4I5N    4MEW   
PDB (IMB)4I5L    4I5N    4MEW   
PDB (RSDB)4I5L    4I5N    4MEW   
Structural Biology KnowledgeBase4I5L    4I5N    4MEW   
SCOP (Structural Classification of Proteins)4I5L    4I5N    4MEW   
CATH (Classification of proteins structures)4I5L    4I5N    4MEW   
SuperfamilyQ9Y5P8
Human Protein AtlasENSG00000167393
Peptide AtlasQ9Y5P8
HPRD02276
IPIIPI00845329   IPI00399006   IPI00555894   IPI00946742   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5P8
IntAct (EBI)Q9Y5P8
FunCoupENSG00000167393
BioGRIDPPP2R3B
STRING (EMBL)PPP2R3B
ZODIACPPP2R3B
Ontologies - Pathways
QuickGOQ9Y5P8
Ontology : AmiGOprotein phosphatase type 2A complex  phosphoprotein phosphatase activity  protein serine/threonine phosphatase activity  calcium ion binding  protein binding  nucleus  nucleoplasm  protein dephosphorylation  cell cycle arrest  protein phosphatase regulator activity  regulation of catalytic activity  
Ontology : EGO-EBIprotein phosphatase type 2A complex  phosphoprotein phosphatase activity  protein serine/threonine phosphatase activity  calcium ion binding  protein binding  nucleus  nucleoplasm  protein dephosphorylation  cell cycle arrest  protein phosphatase regulator activity  regulation of catalytic activity  
Pathways : KEGGmRNA surveillance pathway    PI3K-Akt signaling pathway    Adrenergic signaling in cardiomyocytes    Dopaminergic synapse   
NDEx NetworkPPP2R3B
Atlas of Cancer Signalling NetworkPPP2R3B
Wikipedia pathwaysPPP2R3B
Orthology - Evolution
OrthoDB28227
GeneTree (enSembl)ENSG00000167393
Phylogenetic Trees/Animal Genes : TreeFamPPP2R3B
HOVERGENQ9Y5P8
HOGENOMQ9Y5P8
Homologs : HomoloGenePPP2R3B
Homology/Alignments : Family Browser (UCSC)PPP2R3B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP2R3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP2R3B
dbVarPPP2R3B
ClinVarPPP2R3B
1000_GenomesPPP2R3B 
Exome Variant ServerPPP2R3B
ExAC (Exome Aggregation Consortium)PPP2R3B (select the gene name)
Genetic variants : HAPMAP28227
Genomic Variants (DGV)PPP2R3B [DGVbeta]
DECIPHERPPP2R3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP2R3B 
Mutations
ICGC Data PortalPPP2R3B 
TCGA Data PortalPPP2R3B 
Broad Tumor PortalPPP2R3B
OASIS PortalPPP2R3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP2R3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP2R3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch PPP2R3B
DgiDB (Drug Gene Interaction Database)PPP2R3B
DoCM (Curated mutations)PPP2R3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP2R3B (select a term)
intoGenPPP2R3B
Cancer3DPPP2R3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300339   
Orphanet
MedgenPPP2R3B
Genetic Testing Registry PPP2R3B
NextProtQ9Y5P8 [Medical]
TSGene28227
GENETestsPPP2R3B
Target ValidationPPP2R3B
Huge Navigator PPP2R3B [HugePedia]
snp3D : Map Gene to Disease28227
BioCentury BCIQPPP2R3B
ClinGenPPP2R3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD28227
Chemical/Pharm GKB GenePA134878872
Clinical trialPPP2R3B
Miscellaneous
canSAR (ICR)PPP2R3B (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP2R3B
EVEXPPP2R3B
GoPubMedPPP2R3B
iHOPPPP2R3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Aug 1 17:11:27 CEST 2017

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