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PPP2R5C (protein phosphatase 2, regulatory subunit B', gamma)

Identity

Other namesB56G
PR61G
HGNC (Hugo) PPP2R5C
LocusID (NCBI) 5527
Location 14q32.31
Location_base_pair Starts at 102228135 and ends at 102394328 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PPP2R5C   9311
Entrez_Gene (NCBI)PPP2R5C  5527  protein phosphatase 2, regulatory subunit B', gamma
Cards
GeneCards (Weizmann)PPP2R5C
Ensembl (Hinxton)ENSG00000078304 [Gene_View]  chr14:102228135-102394328 [Contig_View]  PPP2R5C [Vega]
AceView (NCBI)PPP2R5C
Genatlas (Paris)PPP2R5C
SOURCE (Stanford)NM_001161725 NM_001161726 NM_002719 NM_178586 NM_178587 NM_178588
Genomic and cartography
GoldenPath (UCSC)PPP2R5C  -  14q32.31   chr14:102228135-102394328 +  14q32.31   [Description]    (hg19-Feb_2009)
EnsemblPPP2R5C - 14q32.31 [CytoView]
Mapping of homologs : NCBIPPP2R5C [Mapview]
OMIM601645   
Gene and transcription
Genbank (Entrez)AA487513 AA716736 AB451341 AI282996 AI692258
RefSeq transcript (SRS)NM_001161725 NM_001161726 NM_002719 NM_178586 NM_178587 NM_178588
RefSeq transcript (Entrez)NM_001161725 NM_001161726 NM_002719 NM_178586 NM_178587 NM_178588
RefSeq genomic (SRS)AC_000146 NC_000014 NC_018925 NT_026437 NW_001838115 NW_004078079
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NT_026437 NW_001838115 NW_004078079
Consensus coding sequences : CCDS (NCBI)PPP2R5C
Cluster EST : UnigeneHs.368264 [ SRS ] Hs.368264 [ NCBI ]
CGAP (NCI)Hs.368264
Alternative Splicing : Fast-db (Paris)GSHG0009129
Alternative Splicing GalleryENSG00000078304
Gene ExpressionPPP2R5C [ NCBI-GEO ]   PPP2R5C [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13362 (SRS) Q13362 (Uniprot)
NextProtQ13362
With graphics : InterProQ13362
Splice isoforms : SwissVarQ13362(Swissvar)
Domains : Interpro (SRS)ARM-type_fold    PP2A_B56   
Domains : Interpro (EBI)ARM-type_fold    PP2A_B56   
Related proteins : CluSTrQ13362
Domain families : Pfam (SRS)B56 (PF01603)   
Domain families : Pfam (Sanger)B56 (PF01603)   
Domain families : Pfam (NCBI)pfam01603   
DMDM5527
Blocks (Seattle)Q13362
PDB (SRS)2IAE    2JAK    2NPP    2NYL    2NYM    3FGA   
PDB (PDBSum)2IAE    2JAK    2NPP    2NYL    2NYM    3FGA   
PDB (IMB)2IAE    2JAK    2NPP    2NYL    2NYM    3FGA   
PDB (RSDB)2IAE    2JAK    2NPP    2NYL    2NYM    3FGA   
Human Protein AtlasENSG00000078304
HPRD03385
IPIIPI00012834   IPI00185637   IPI00220145   IPI00384127   IPI01026231   IPI01026342   IPI01026441   IPI01026567   IPI01025794   IPI01026019   IPI01025215   IPI01025329   IPI01025478   IPI01025594   IPI00935184   IPI00442098   
Protein Interaction databases
DIP (DOE-UCLA)Q13362
IntAct (EBI)Q13362
FunCoupENSG00000078304
REACTOMEPPP2R5C
Protein Interaction Database5527
BioGRIDPPP2R5C
InParanoidQ13362
Interologous Interaction database Q13362
IntegromeDBPPP2R5C
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PPP2R5C
SNP (GeneSNP Utah)PPP2R5C
SNP : HGBasePPP2R5C
Genetic variants : HAPMAPPPP2R5C
Somatic Mutations in Cancer : COSMICPPP2R5C 
CONAN: Copy Number AnalysisPPP2R5C 
Mutations and Diseases : HGMDPPP2R5C
OMIM601645   
GENETests601645   
Disease Genetic AssociationPPP2R5C
Huge Navigator PPP2R5C [HugePedia]  PPP2R5C [HugeCancerGEM]
Genomic VariantsPPP2R5C  PPP2R5C [DGVbeta]
snp3D : Map Gene to Disease5527
General knowledge
Homologs : HomoloGenePPP2R5C
Homology/Alignments : Family Browser (UCSC)PPP2R5C
Phylogenetic Trees/Animal Genes : TreeFamPPP2R5C
Chemical/Protein Interactions : CTD5527
Chemical/Pharm GKB GenePA33674
Clinical trialPPP2R5C
Cancer Resource (Charite)ENSG00000078304
Ontology : AmiGOprotein phosphatase type 2A complex  protein phosphatase type 2A complex  chromosome, centromeric region  protein binding  nucleus  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  signal transduction  negative regulation of cell proliferation  protein phosphatase type 2A regulator activity  protein phosphatase type 2A regulator activity  intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  proteasomal ubiquitin-dependent protein catabolic process  
Ontology : EGO-EBIprotein phosphatase type 2A complex  protein phosphatase type 2A complex  chromosome, centromeric region  protein binding  nucleus  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  signal transduction  negative regulation of cell proliferation  protein phosphatase type 2A regulator activity  protein phosphatase type 2A regulator activity  intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  proteasomal ubiquitin-dependent protein catabolic process  
Other databases
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
PubGenePPP2R5C
iHOPPPP2R5C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:37:05 CEST 2013

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