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PPP4R4 (protein phosphatase 4 regulatory subunit 4)

Identity

Alias_namesKIAA1622
KIAA1622
Alias_symbol (synonym)PP4R4
CFAP14
Other alias
HGNC (Hugo) PPP4R4
LocusID (NCBI) 57718
Atlas_Id 72156
Location 14q32.12  [Link to chromosome band 14q32]
Location_base_pair Starts at 94175461 and ends at 94279735 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP4R4   23788
Cards
Entrez_Gene (NCBI)PPP4R4  57718  protein phosphatase 4 regulatory subunit 4
AliasesCFAP14; KIAA1622; PP4R4
GeneCards (Weizmann)PPP4R4
Ensembl hg19 (Hinxton)ENSG00000119698 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119698 [Gene_View]  chr14:94175461-94279735 [Contig_View]  PPP4R4 [Vega]
ICGC DataPortalENSG00000119698
TCGA cBioPortalPPP4R4
AceView (NCBI)PPP4R4
Genatlas (Paris)PPP4R4
WikiGenes57718
SOURCE (Princeton)PPP4R4
Genetics Home Reference (NIH)PPP4R4
Genomic and cartography
GoldenPath hg38 (UCSC)PPP4R4  -     chr14:94175461-94279735 +  14q32.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP4R4  -     14q32.12   [Description]    (hg19-Feb_2009)
EnsemblPPP4R4 - 14q32.12 [CytoView hg19]  PPP4R4 - 14q32.12 [CytoView hg38]
Mapping of homologs : NCBIPPP4R4 [Mapview hg19]  PPP4R4 [Mapview hg38]
OMIM616790   
Gene and transcription
Genbank (Entrez)AB046842 AK303722 BC002650 BC068491 BI546744
RefSeq transcript (Entrez)NM_001348142 NM_001348143 NM_001348144 NM_001348145 NM_020958 NM_058237
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_187601
Consensus coding sequences : CCDS (NCBI)PPP4R4
Cluster EST : UnigeneHs.259599 [ NCBI ]
CGAP (NCI)Hs.259599
Alternative Splicing GalleryENSG00000119698
Gene ExpressionPPP4R4 [ NCBI-GEO ]   PPP4R4 [ EBI - ARRAY_EXPRESS ]   PPP4R4 [ SEEK ]   PPP4R4 [ MEM ]
Gene Expression Viewer (FireBrowse)PPP4R4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57718
GTEX Portal (Tissue expression)PPP4R4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6NUP7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6NUP7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6NUP7
Splice isoforms : SwissVarQ6NUP7
PhosPhoSitePlusQ6NUP7
Domaine pattern : Prosite (Expaxy)HEAT_REPEAT (PS50077)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    HEAT_type_2   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PPP4R4
DMDM Disease mutations57718
Blocks (Seattle)PPP4R4
SuperfamilyQ6NUP7
Human Protein AtlasENSG00000119698
Peptide AtlasQ6NUP7
HPRD13878
IPIIPI00014515   IPI00024856   IPI01025086   IPI01024707   IPI01024897   
Protein Interaction databases
DIP (DOE-UCLA)Q6NUP7
IntAct (EBI)Q6NUP7
FunCoupENSG00000119698
BioGRIDPPP4R4
STRING (EMBL)PPP4R4
ZODIACPPP4R4
Ontologies - Pathways
QuickGOQ6NUP7
Ontology : AmiGOprotein binding  cytoplasm  cytosol  protein serine/threonine phosphatase complex  protein phosphatase regulator activity  negative regulation of phosphoprotein phosphatase activity  regulation of protein serine/threonine phosphatase activity  
Ontology : EGO-EBIprotein binding  cytoplasm  cytosol  protein serine/threonine phosphatase complex  protein phosphatase regulator activity  negative regulation of phosphoprotein phosphatase activity  regulation of protein serine/threonine phosphatase activity  
NDEx NetworkPPP4R4
Atlas of Cancer Signalling NetworkPPP4R4
Wikipedia pathwaysPPP4R4
Orthology - Evolution
OrthoDB57718
GeneTree (enSembl)ENSG00000119698
Phylogenetic Trees/Animal Genes : TreeFamPPP4R4
HOVERGENQ6NUP7
HOGENOMQ6NUP7
Homologs : HomoloGenePPP4R4
Homology/Alignments : Family Browser (UCSC)PPP4R4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP4R4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP4R4
dbVarPPP4R4
ClinVarPPP4R4
1000_GenomesPPP4R4 
Exome Variant ServerPPP4R4
ExAC (Exome Aggregation Consortium)PPP4R4 (select the gene name)
Genetic variants : HAPMAP57718
Genomic Variants (DGV)PPP4R4 [DGVbeta]
DECIPHERPPP4R4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP4R4 
Mutations
ICGC Data PortalPPP4R4 
TCGA Data PortalPPP4R4 
Broad Tumor PortalPPP4R4
OASIS PortalPPP4R4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP4R4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP4R4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP4R4
DgiDB (Drug Gene Interaction Database)PPP4R4
DoCM (Curated mutations)PPP4R4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP4R4 (select a term)
intoGenPPP4R4
Cancer3DPPP4R4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616790   
Orphanet
MedgenPPP4R4
Genetic Testing Registry PPP4R4
NextProtQ6NUP7 [Medical]
TSGene57718
GENETestsPPP4R4
Target ValidationPPP4R4
Huge Navigator PPP4R4 [HugePedia]
snp3D : Map Gene to Disease57718
BioCentury BCIQPPP4R4
ClinGenPPP4R4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57718
Chemical/Pharm GKB GenePA164724938
Clinical trialPPP4R4
Miscellaneous
canSAR (ICR)PPP4R4 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP4R4
EVEXPPP4R4
GoPubMedPPP4R4
iHOPPPP4R4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:36:24 CEST 2017

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