PPP6R1 (protein phosphatase 6 regulatory subunit 1)

2014-11-01  

Identity

HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
KIAA1115,PP6R1,SAP190,SAPS1
FUSION GENES

Other Information

Locus ID:

NCBI: 22870
MIM: 610875
HGNC: 29195
Ensembl: ENSG00000105063

Variants:

dbSNP: 22870
ClinVar: 22870
TCGA: ENSG00000105063
COSMIC: PPP6R1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105063ENST00000412770Q9UPN7
ENSG00000105063ENST00000587283Q9UPN7
ENSG00000105063ENST00000592242K7EM28

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
COPII (Coat Protein 2) Mediated Vesicle TransportREACTOMER-HSA-204005
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
222987872012PP6 regulatory subunit R1 is bidentate anchor for targeting protein phosphatase-6 to DNA-dependent protein kinase.18

Citation

Dessen P

PPP6R1 (protein phosphatase 6 regulatory subunit 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72158/ppp6r1