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PPRC1 (PPARG related coactivator 1)

Identity

Alias (NCBI)PRC
HGNC (Hugo) PPRC1
HGNC Alias symbPRC
KIAA0595
MGC74642
HGNC Alias namepgc-1 related coactivator
HGNC Previous nameperoxisome proliferative activated receptor, gamma, coactivator-related 1
LocusID (NCBI) 23082
Atlas_Id 47683
Location 10q24.32  [Link to chromosome band 10q24]
Location_base_pair Starts at 102133040 and ends at 102150333 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HACE1 (6q16.3) / PPRC1 (10q24.32)IGHV3OR16-7 () / PPRC1 (10q24.32)PPRC1 (10q24.32) / PPRC1 (10q24.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PPRC1   30025
Cards
Entrez_Gene (NCBI)PPRC1    PPARG related coactivator 1
AliasesPRC
GeneCards (Weizmann)PPRC1
Ensembl hg19 (Hinxton)ENSG00000148840 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148840 [Gene_View]  ENSG00000148840 [Sequence]  chr10:102133040-102150333 [Contig_View]  PPRC1 [Vega]
ICGC DataPortalENSG00000148840
TCGA cBioPortalPPRC1
AceView (NCBI)PPRC1
Genatlas (Paris)PPRC1
SOURCE (Princeton)PPRC1
Genetics Home Reference (NIH)PPRC1
Genomic and cartography
GoldenPath hg38 (UCSC)PPRC1  -     chr10:102133040-102150333 +  10q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPRC1  -     10q24.32   [Description]    (hg19-Feb_2009)
GoldenPathPPRC1 - 10q24.32 [CytoView hg19]  PPRC1 - 10q24.32 [CytoView hg38]
ImmunoBaseENSG00000148840
Genome Data Viewer NCBIPPRC1 [Mapview hg19]  
OMIM617462   
Gene and transcription
Genbank (Entrez)AB011167 AF325193 AK025691 AK095248 AK299885
RefSeq transcript (Entrez)NM_001288727 NM_001288728 NM_015062
Consensus coding sequences : CCDS (NCBI)PPRC1
Gene ExpressionPPRC1 [ NCBI-GEO ]   PPRC1 [ EBI - ARRAY_EXPRESS ]   PPRC1 [ SEEK ]   PPRC1 [ MEM ]
Gene Expression Viewer (FireBrowse)PPRC1 [ Firebrowse - Broad ]
GenevisibleExpression of PPRC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23082
GTEX Portal (Tissue expression)PPRC1
Human Protein AtlasENSG00000148840-PPRC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VV67   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VV67  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VV67
PhosPhoSitePlusQ5VV67
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait_sf    PGC-1    PRC    PRC_RRM    RBD_domain_sf    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)PPRC1
SuperfamilyQ5VV67
AlphaFold pdb e-kbQ5VV67   
Human Protein Atlas [tissue]ENSG00000148840-PPRC1 [tissue]
HPRD15173
Protein Interaction databases
DIP (DOE-UCLA)Q5VV67
IntAct (EBI)Q5VV67
BioGRIDPPRC1
STRING (EMBL)PPRC1
ZODIACPPRC1
Ontologies - Pathways
QuickGOQ5VV67
Ontology : AmiGORNA binding  nucleus  nucleoplasm  nucleoplasm  mitochondrion organization  transcription factor binding  nuclear receptor coactivator activity  positive regulation of transcription by RNA polymerase II  positive regulation of DNA-binding transcription factor activity  
Ontology : EGO-EBIRNA binding  nucleus  nucleoplasm  nucleoplasm  mitochondrion organization  transcription factor binding  nuclear receptor coactivator activity  positive regulation of transcription by RNA polymerase II  positive regulation of DNA-binding transcription factor activity  
NDEx NetworkPPRC1
Atlas of Cancer Signalling NetworkPPRC1
Wikipedia pathwaysPPRC1
Orthology - Evolution
OrthoDB23082
GeneTree (enSembl)ENSG00000148840
Phylogenetic Trees/Animal Genes : TreeFamPPRC1
Homologs : HomoloGenePPRC1
Homology/Alignments : Family Browser (UCSC)PPRC1
Gene fusions - Rearrangements
Fusion : QuiverPPRC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPRC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPRC1
dbVarPPRC1
ClinVarPPRC1
MonarchPPRC1
1000_GenomesPPRC1 
Exome Variant ServerPPRC1
GNOMAD BrowserENSG00000148840
Varsome BrowserPPRC1
ACMGPPRC1 variants
VarityQ5VV67
Genomic Variants (DGV)PPRC1 [DGVbeta]
DECIPHERPPRC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPRC1 
Mutations
ICGC Data PortalPPRC1 
TCGA Data PortalPPRC1 
Broad Tumor PortalPPRC1
OASIS PortalPPRC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPRC1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPPRC1
Mutations and Diseases : HGMDPPRC1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPPRC1
DgiDB (Drug Gene Interaction Database)PPRC1
DoCM (Curated mutations)PPRC1
CIViC (Clinical Interpretations of Variants in Cancer)PPRC1
Cancer3DPPRC1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617462   
Orphanet
DisGeNETPPRC1
MedgenPPRC1
Genetic Testing Registry PPRC1
NextProtQ5VV67 [Medical]
GENETestsPPRC1
Target ValidationPPRC1
Huge Navigator PPRC1 [HugePedia]
ClinGenPPRC1
Clinical trials, drugs, therapy
MyCancerGenomePPRC1
Protein Interactions : CTDPPRC1
Pharm GKB GenePA134886297
PharosQ5VV67
Clinical trialPPRC1
Miscellaneous
canSAR (ICR)PPRC1
HarmonizomePPRC1
DataMed IndexPPRC1
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPPRC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:26:35 CEST 2021

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