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PPTC7 (PTC7 protein phosphatase homolog)

Identity

Alias_namesPTC7 protein phosphatase homolog (S. cerevisiae)
Alias_symbol (synonym)TA-PP2C
Other aliasTAPP2C
HGNC (Hugo) PPTC7
LocusID (NCBI) 160760
Atlas_Id 72162
Location 12q24.11  [Link to chromosome band 12q24]
Location_base_pair Starts at 110534432 and ends at 110583259 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PPTC7 (12q24.11) / ALS2CR12 (2q33.1)PPTC7 (12q24.11) / HVCN1 (12q24.11)PPTC7 (12q24.11) / RP11-24B21.1 ()
PPTC7 ALS2CR12PPTC7 RP11-24B21.1PPTC7 HVCN1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPTC7   30695
Cards
Entrez_Gene (NCBI)PPTC7  160760  PTC7 protein phosphatase homolog
AliasesTA-PP2C; TAPP2C
GeneCards (Weizmann)PPTC7
Ensembl hg19 (Hinxton)ENSG00000196850 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196850 [Gene_View]  chr12:110534432-110583259 [Contig_View]  PPTC7 [Vega]
ICGC DataPortalENSG00000196850
TCGA cBioPortalPPTC7
AceView (NCBI)PPTC7
Genatlas (Paris)PPTC7
WikiGenes160760
SOURCE (Princeton)PPTC7
Genetics Home Reference (NIH)PPTC7
Genomic and cartography
GoldenPath hg38 (UCSC)PPTC7  -     chr12:110534432-110583259 -  12q24.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPTC7  -     12q24.11   [Description]    (hg19-Feb_2009)
EnsemblPPTC7 - 12q24.11 [CytoView hg19]  PPTC7 - 12q24.11 [CytoView hg38]
Mapping of homologs : NCBIPPTC7 [Mapview hg19]  PPTC7 [Mapview hg38]
OMIM609668   
Gene and transcription
Genbank (Entrez)AF385435 AK098051 AK124744 AY357944 BC031339
RefSeq transcript (Entrez)NM_139283
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPTC7
Cluster EST : UnigeneHs.13854 [ NCBI ]
CGAP (NCI)Hs.13854
Alternative Splicing GalleryENSG00000196850
Gene ExpressionPPTC7 [ NCBI-GEO ]   PPTC7 [ EBI - ARRAY_EXPRESS ]   PPTC7 [ SEEK ]   PPTC7 [ MEM ]
Gene Expression Viewer (FireBrowse)PPTC7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)160760
GTEX Portal (Tissue expression)PPTC7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NI37   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NI37  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NI37
Splice isoforms : SwissVarQ8NI37
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
PhosPhoSitePlusQ8NI37
Domaine pattern : Prosite (Expaxy)PPM_2 (PS51746)   
Domains : Interpro (EBI)PPM-type_phosphatase_dom   
Domain families : Pfam (Sanger)SpoIIE (PF07228)   
Domain families : Pfam (NCBI)pfam07228   
Domain families : Smart (EMBL)PP2C_SIG (SM00331)  PP2Cc (SM00332)  
Conserved Domain (NCBI)PPTC7
DMDM Disease mutations160760
Blocks (Seattle)PPTC7
SuperfamilyQ8NI37
Human Protein AtlasENSG00000196850
Peptide AtlasQ8NI37
HPRD18141
IPIIPI00169326   
Protein Interaction databases
DIP (DOE-UCLA)Q8NI37
IntAct (EBI)Q8NI37
FunCoupENSG00000196850
BioGRIDPPTC7
STRING (EMBL)PPTC7
ZODIACPPTC7
Ontologies - Pathways
QuickGOQ8NI37
Ontology : AmiGOphosphoprotein phosphatase activity  mitochondrion  protein dephosphorylation  metal ion binding  
Ontology : EGO-EBIphosphoprotein phosphatase activity  mitochondrion  protein dephosphorylation  metal ion binding  
NDEx NetworkPPTC7
Atlas of Cancer Signalling NetworkPPTC7
Wikipedia pathwaysPPTC7
Orthology - Evolution
OrthoDB160760
GeneTree (enSembl)ENSG00000196850
Phylogenetic Trees/Animal Genes : TreeFamPPTC7
HOVERGENQ8NI37
HOGENOMQ8NI37
Homologs : HomoloGenePPTC7
Homology/Alignments : Family Browser (UCSC)PPTC7
Gene fusions - Rearrangements
Fusion: TCGAPPTC7 ALS2CR12
Fusion: TCGAPPTC7 RP11-24B21.1
Fusion: TCGAPPTC7 HVCN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPTC7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPTC7
dbVarPPTC7
ClinVarPPTC7
1000_GenomesPPTC7 
Exome Variant ServerPPTC7
ExAC (Exome Aggregation Consortium)PPTC7 (select the gene name)
Genetic variants : HAPMAP160760
Genomic Variants (DGV)PPTC7 [DGVbeta]
DECIPHERPPTC7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPTC7 
Mutations
ICGC Data PortalPPTC7 
TCGA Data PortalPPTC7 
Broad Tumor PortalPPTC7
OASIS PortalPPTC7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPTC7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPTC7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch PPTC7
DgiDB (Drug Gene Interaction Database)PPTC7
DoCM (Curated mutations)PPTC7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPTC7 (select a term)
intoGenPPTC7
Cancer3DPPTC7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609668   
Orphanet
MedgenPPTC7
Genetic Testing Registry PPTC7
NextProtQ8NI37 [Medical]
TSGene160760
GENETestsPPTC7
Target ValidationPPTC7
Huge Navigator PPTC7 [HugePedia]
snp3D : Map Gene to Disease160760
BioCentury BCIQPPTC7
ClinGenPPTC7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD160760
Chemical/Pharm GKB GenePA143485580
Clinical trialPPTC7
Miscellaneous
canSAR (ICR)PPTC7 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPTC7
EVEXPPTC7
GoPubMedPPTC7
iHOPPPTC7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:35:09 CEST 2017

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