PRAF2 (PRA1 domain family member 2)

2003-12-01  

Identity

HGNC
LOCATION
Xp11.23
LOCUSID
ALIAS
JM4,Yip6a
FUSION GENES

Other Information

Locus ID:

NCBI: 11230
MIM: 300840
HGNC: 28911
Ensembl: ENSG00000243279

Variants:

dbSNP: 11230
ClinVar: 11230
TCGA: ENSG00000243279
COSMIC: PRAF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000243279ENST00000376386A6NP52
ENSG00000243279ENST00000553851O60831
ENSG00000243279ENST00000553851A0A024QZ22

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
212035332010Praf2 is a novel Bcl-xL/Bcl-2 interacting protein with the ability to modulate survival of cancer cells.21
157576712005JM4 is a four-transmembrane protein binding to the CCR5 receptor.14
164811312006Genomic organization, expression profile, and characterization of the new protein PRA1 domain family, member 2 (PRAF2).10
204121212010Subcellular distribution and expression of prenylated Rab acceptor 1 domain family, member 2 (PRAF2) in malignant glioma: Influence on cell survival and migration.9
179751422007Expression of prenylated Rab acceptor 1 domain family, member 2 (PRAF2) in neuroblastoma: correlation with clinical features, cellular localization, and cerulenin-mediated apoptosis regulation.8
183959782008Expression profile of PRAF2 in the human brain and enrichment in synaptic vesicles.8
234403292013PRAF2 stimulates cell proliferation and migration and predicts poor prognosis in neuroblastoma.5
312006702019PRAF2 overexpression predicts poor prognosis and promotes tumorigenesis in esophageal squamous cell carcinoma.1

Citation

Dessen P

PRAF2 (PRA1 domain family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41040/praf2