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PRAG1 (PEAK1 related kinase activating pseudokinase 1)

Identity

Other aliasNACK
PEAK2
PRAGMIN
SGK223
HGNC (Hugo) PRAG1
LocusID (NCBI) 157285
Atlas_Id 56711
Location 8p23.1  [Link to chromosome band 8p23]
Location_base_pair Starts at 8175258 and ends at 8239344 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)PRAG1   25438
Cards
Entrez_Gene (NCBI)PRAG1  157285  PEAK1 related kinase activating pseudokinase 1
AliasesNACK; PEAK2; PRAGMIN; SGK223
GeneCards (Weizmann)PRAG1
Ensembl hg19 (Hinxton) [Gene_View]  chr8:8175258-8239344 [Contig_View]  PRAG1 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr8:8175258-8239344 [Contig_View]  PRAG1 [Vega]
TCGA cBioPortalPRAG1
AceView (NCBI)PRAG1
Genatlas (Paris)PRAG1
WikiGenes157285
SOURCE (Princeton)PRAG1
Genetics Home Reference (NIH)PRAG1
Genomic and cartography
GoldenPath hg19 (UCSC)PRAG1  -     chr8:8175258-8239344 -  8p23.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PRAG1  -     8p23.1   [Description]    (hg38-Dec_2013)
EnsemblPRAG1 - 8p23.1 [CytoView hg19]  PRAG1 - 8p23.1 [CytoView hg38]
Mapping of homologs : NCBIPRAG1 [Mapview hg19]  PRAG1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF075060 AK122582 AL833872 BX420505
RefSeq transcript (Entrez)NM_001080826
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRAG1
Cluster EST : UnigeneHs.657673 [ NCBI ]
CGAP (NCI)Hs.657673
Gene ExpressionPRAG1 [ NCBI-GEO ]   PRAG1 [ EBI - ARRAY_EXPRESS ]   PRAG1 [ SEEK ]   PRAG1 [ MEM ]
Gene Expression Viewer (FireBrowse)PRAG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)157285
GTEX Portal (Tissue expression)PRAG1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86YV5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86YV5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86YV5
Splice isoforms : SwissVarQ86YV5
Catalytic activity : Enzyme2.7.10.2 [ Enzyme-Expasy ]   2.7.10.22.7.10.2 [ IntEnz-EBI ]   2.7.10.2 [ BRENDA ]   2.7.10.2 [ KEGG ]   
PhosPhoSitePlusQ86YV5
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_TYR (PS00109)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Tyr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)PRAG1
DMDM Disease mutations157285
Blocks (Seattle)PRAG1
SuperfamilyQ86YV5
Peptide AtlasQ86YV5
IPIIPI00739386   
Protein Interaction databases
DIP (DOE-UCLA)Q86YV5
IntAct (EBI)Q86YV5
BioGRIDPRAG1
STRING (EMBL)PRAG1
ZODIACPRAG1
Ontologies - Pathways
QuickGOQ86YV5
Ontology : AmiGOprotein kinase activity  non-membrane spanning protein tyrosine kinase activity  ATP binding  peptidyl-tyrosine phosphorylation  
Ontology : EGO-EBIprotein kinase activity  non-membrane spanning protein tyrosine kinase activity  ATP binding  peptidyl-tyrosine phosphorylation  
NDEx NetworkPRAG1
Atlas of Cancer Signalling NetworkPRAG1
Wikipedia pathwaysPRAG1
Orthology - Evolution
OrthoDB157285
Phylogenetic Trees/Animal Genes : TreeFamPRAG1
HOVERGENQ86YV5
HOGENOMQ86YV5
Homologs : HomoloGenePRAG1
Homology/Alignments : Family Browser (UCSC)PRAG1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRAG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRAG1
dbVarPRAG1
ClinVarPRAG1
1000_GenomesPRAG1 
Exome Variant ServerPRAG1
ExAC (Exome Aggregation Consortium)PRAG1 (select the gene name)
Genetic variants : HAPMAP157285
Genomic Variants (DGV)PRAG1 [DGVbeta]
DECIPHER (Syndromes)8:8175258-8239344  
CONAN: Copy Number AnalysisPRAG1 
Mutations
ICGC Data PortalPRAG1 
TCGA Data PortalPRAG1 
Broad Tumor PortalPRAG1
OASIS PortalPRAG1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPRAG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRAG1
DgiDB (Drug Gene Interaction Database)PRAG1
DoCM (Curated mutations)PRAG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRAG1 (select a term)
intoGenPRAG1
Cancer3DPRAG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPRAG1
Genetic Testing Registry PRAG1
NextProtQ86YV5 [Medical]
TSGene157285
GENETestsPRAG1
Huge Navigator PRAG1 [HugePedia]
snp3D : Map Gene to Disease157285
BioCentury BCIQPRAG1
ClinGenPRAG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD157285
Clinical trialPRAG1
Miscellaneous
canSAR (ICR)PRAG1 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRAG1
EVEXPRAG1
GoPubMedPRAG1
iHOPPRAG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:22:42 CET 2017

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