Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PRAP1 (proline rich acidic protein 1)

Identity

Alias (NCBI)PRO1195
UPA
HGNC (Hugo) PRAP1
HGNC Alias symbUPA
LocusID (NCBI) 118471
Atlas_Id 53412
Location 10q26.3  [Link to chromosome band 10q26]
Location_base_pair Starts at 133347373 and ends at 133352683 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PRAP1   23304
Cards
Entrez_Gene (NCBI)PRAP1    proline rich acidic protein 1
AliasesPRO1195; UPA
GeneCards (Weizmann)PRAP1
Ensembl hg19 (Hinxton)ENSG00000165828 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165828 [Gene_View]  ENSG00000165828 [Sequence]  chr10:133347373-133352683 [Contig_View]  PRAP1 [Vega]
ICGC DataPortalENSG00000165828
TCGA cBioPortalPRAP1
AceView (NCBI)PRAP1
Genatlas (Paris)PRAP1
SOURCE (Princeton)PRAP1
Genetics Home Reference (NIH)PRAP1
Genomic and cartography
GoldenPath hg38 (UCSC)PRAP1  -     chr10:133347373-133352683 +  10q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRAP1  -     10q26.3   [Description]    (hg19-Feb_2009)
GoldenPathPRAP1 - 10q26.3 [CytoView hg19]  PRAP1 - 10q26.3 [CytoView hg38]
ImmunoBaseENSG00000165828
Genome Data Viewer NCBIPRAP1 [Mapview hg19]  
OMIM609776   
Gene and transcription
Genbank (Entrez)AF123768 AF421885 AY158074 AY358908 BC029447
RefSeq transcript (Entrez)NM_001145201 NM_145202
Consensus coding sequences : CCDS (NCBI)PRAP1
Gene ExpressionPRAP1 [ NCBI-GEO ]   PRAP1 [ EBI - ARRAY_EXPRESS ]   PRAP1 [ SEEK ]   PRAP1 [ MEM ]
Gene Expression Viewer (FireBrowse)PRAP1 [ Firebrowse - Broad ]
GenevisibleExpression of PRAP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)118471
GTEX Portal (Tissue expression)PRAP1
Human Protein AtlasENSG00000165828-PRAP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96NZ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96NZ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96NZ9
PhosPhoSitePlusQ96NZ9
Domains : Interpro (EBI)PRAP   
Domain families : Pfam (Sanger)PRAP (PF15314)   
Domain families : Pfam (NCBI)pfam15314   
Conserved Domain (NCBI)PRAP1
SuperfamilyQ96NZ9
AlphaFold pdb e-kbQ96NZ9   
Human Protein Atlas [tissue]ENSG00000165828-PRAP1 [tissue]
HPRD17898
Protein Interaction databases
DIP (DOE-UCLA)Q96NZ9
IntAct (EBI)Q96NZ9
BioGRIDPRAP1
STRING (EMBL)PRAP1
ZODIACPRAP1
Ontologies - Pathways
QuickGOQ96NZ9
Ontology : AmiGOprotein binding  extracellular region  endoplasmic reticulum  cellular response to DNA damage stimulus  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  triglyceride binding  negative regulation of apoptotic process  negative regulation of apoptotic process  cellular response to X-ray  deactivation of mitotic spindle assembly checkpoint  positive regulation of intestinal lipid absorption  positive regulation of triglyceride transport  positive regulation of phospholipid transport  
Ontology : EGO-EBIprotein binding  extracellular region  endoplasmic reticulum  cellular response to DNA damage stimulus  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  triglyceride binding  negative regulation of apoptotic process  negative regulation of apoptotic process  cellular response to X-ray  deactivation of mitotic spindle assembly checkpoint  positive regulation of intestinal lipid absorption  positive regulation of triglyceride transport  positive regulation of phospholipid transport  
NDEx NetworkPRAP1
Atlas of Cancer Signalling NetworkPRAP1
Wikipedia pathwaysPRAP1
Orthology - Evolution
OrthoDB118471
GeneTree (enSembl)ENSG00000165828
Phylogenetic Trees/Animal Genes : TreeFamPRAP1
Homologs : HomoloGenePRAP1
Homology/Alignments : Family Browser (UCSC)PRAP1
Gene fusions - Rearrangements
Fusion : QuiverPRAP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRAP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRAP1
dbVarPRAP1
ClinVarPRAP1
MonarchPRAP1
1000_GenomesPRAP1 
Exome Variant ServerPRAP1
GNOMAD BrowserENSG00000165828
Varsome BrowserPRAP1
ACMGPRAP1 variants
VarityQ96NZ9
Genomic Variants (DGV)PRAP1 [DGVbeta]
DECIPHERPRAP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRAP1 
Mutations
ICGC Data PortalPRAP1 
TCGA Data PortalPRAP1 
Broad Tumor PortalPRAP1
OASIS PortalPRAP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRAP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPRAP1
Mutations and Diseases : HGMDPRAP1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPRAP1
DgiDB (Drug Gene Interaction Database)PRAP1
DoCM (Curated mutations)PRAP1
CIViC (Clinical Interpretations of Variants in Cancer)PRAP1
Cancer3DPRAP1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609776   
Orphanet
DisGeNETPRAP1
MedgenPRAP1
Genetic Testing Registry PRAP1
NextProtQ96NZ9 [Medical]
GENETestsPRAP1
Target ValidationPRAP1
Huge Navigator PRAP1 [HugePedia]
ClinGenPRAP1
Clinical trials, drugs, therapy
MyCancerGenomePRAP1
Protein Interactions : CTDPRAP1
Pharm GKB GenePA134981678
PharosQ96NZ9
Clinical trialPRAP1
Miscellaneous
canSAR (ICR)PRAP1
HarmonizomePRAP1
DataMed IndexPRAP1
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPRAP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:26:41 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.