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PRC1 (protein regulator of cytokinesis 1)

Identity

Alias_symbol (synonym)ASE1
Other alias
HGNC (Hugo) PRC1
LocusID (NCBI) 9055
Atlas_Id 41829
Location 15q26.1  [Link to chromosome band 15q26]
Location_base_pair Starts at 90966038 and ends at 90994651 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IGFBP5 (2q35) / PRC1 (15q26.1)IQGAP1 (15q26.1) / PRC1 (15q26.1)PRC1 (15q26.1) / RCCD1 (15q26.1)
PRC1 (15q26.1) / VPS33B (15q26.1)RCCD1 (15q26.1) / PRC1 (15q26.1)PRC1 15q26.1 / VPS33B 15q26.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRC1   9341
Cards
Entrez_Gene (NCBI)PRC1  9055  protein regulator of cytokinesis 1
AliasesASE1
GeneCards (Weizmann)PRC1
Ensembl hg19 (Hinxton)ENSG00000198901 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198901 [Gene_View]  chr15:90966038-90994651 [Contig_View]  PRC1 [Vega]
ICGC DataPortalENSG00000198901
TCGA cBioPortalPRC1
AceView (NCBI)PRC1
Genatlas (Paris)PRC1
WikiGenes9055
SOURCE (Princeton)PRC1
Genetics Home Reference (NIH)PRC1
Genomic and cartography
GoldenPath hg38 (UCSC)PRC1  -     chr15:90966038-90994651 -  15q26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRC1  -     15q26.1   [Description]    (hg19-Feb_2009)
EnsemblPRC1 - 15q26.1 [CytoView hg19]  PRC1 - 15q26.1 [CytoView hg38]
Mapping of homologs : NCBIPRC1 [Mapview hg19]  PRC1 [Mapview hg38]
OMIM603484   
Gene and transcription
Genbank (Entrez)AF044588 AK297117 AK304094 AK312600 BC003138
RefSeq transcript (Entrez)NM_001267580 NM_003981 NM_199413 NM_199414
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRC1
Cluster EST : UnigeneHs.366401 [ NCBI ]
CGAP (NCI)Hs.366401
Alternative Splicing GalleryENSG00000198901
Gene ExpressionPRC1 [ NCBI-GEO ]   PRC1 [ EBI - ARRAY_EXPRESS ]   PRC1 [ SEEK ]   PRC1 [ MEM ]
Gene Expression Viewer (FireBrowse)PRC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9055
GTEX Portal (Tissue expression)PRC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43663   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43663  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43663
Splice isoforms : SwissVarO43663
PhosPhoSitePlusO43663
Domains : Interpro (EBI)MAP65_Ase1_PRC1    PRC1   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PRC1
DMDM Disease mutations9055
Blocks (Seattle)PRC1
PDB (SRS)3NRX    3NRY    4L3I    4L6Y    5KMG   
PDB (PDBSum)3NRX    3NRY    4L3I    4L6Y    5KMG   
PDB (IMB)3NRX    3NRY    4L3I    4L6Y    5KMG   
PDB (RSDB)3NRX    3NRY    4L3I    4L6Y    5KMG   
Structural Biology KnowledgeBase3NRX    3NRY    4L3I    4L6Y    5KMG   
SCOP (Structural Classification of Proteins)3NRX    3NRY    4L3I    4L6Y    5KMG   
CATH (Classification of proteins structures)3NRX    3NRY    4L3I    4L6Y    5KMG   
SuperfamilyO43663
Human Protein AtlasENSG00000198901
Peptide AtlasO43663
HPRD17899
IPIIPI00022629   IPI00645623   IPI00915034   IPI01026128   IPI01026500   IPI01026367   IPI00399304   IPI00942190   
Protein Interaction databases
DIP (DOE-UCLA)O43663
IntAct (EBI)O43663
FunCoupENSG00000198901
BioGRIDPRC1
STRING (EMBL)PRC1
ZODIACPRC1
Ontologies - Pathways
QuickGOO43663
Ontology : AmiGOmitotic spindle elongation  cytokinesis  spindle pole  microtubule bundle formation  protein binding  nucleus  nucleoplasm  spindle  cytosol  spindle microtubule  plasma membrane  microtubule binding  positive regulation of cell proliferation  microtubule cytoskeleton  kinesin binding  protein kinase binding  midbody  contractile ring  
Ontology : EGO-EBImitotic spindle elongation  cytokinesis  spindle pole  microtubule bundle formation  protein binding  nucleus  nucleoplasm  spindle  cytosol  spindle microtubule  plasma membrane  microtubule binding  positive regulation of cell proliferation  microtubule cytoskeleton  kinesin binding  protein kinase binding  midbody  contractile ring  
NDEx NetworkPRC1
Atlas of Cancer Signalling NetworkPRC1
Wikipedia pathwaysPRC1
Orthology - Evolution
OrthoDB9055
GeneTree (enSembl)ENSG00000198901
Phylogenetic Trees/Animal Genes : TreeFamPRC1
HOVERGENO43663
HOGENOMO43663
Homologs : HomoloGenePRC1
Homology/Alignments : Family Browser (UCSC)PRC1
Gene fusions - Rearrangements
Fusion : MitelmanPRC1/VPS33B [15q26.1/15q26.1]  
Fusion: TCGAPRC1 15q26.1 VPS33B 15q26.1 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRC1
dbVarPRC1
ClinVarPRC1
1000_GenomesPRC1 
Exome Variant ServerPRC1
ExAC (Exome Aggregation Consortium)PRC1 (select the gene name)
Genetic variants : HAPMAP9055
Genomic Variants (DGV)PRC1 [DGVbeta]
DECIPHERPRC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRC1 
Mutations
ICGC Data PortalPRC1 
TCGA Data PortalPRC1 
Broad Tumor PortalPRC1
OASIS PortalPRC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRC1
DgiDB (Drug Gene Interaction Database)PRC1
DoCM (Curated mutations)PRC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRC1 (select a term)
intoGenPRC1
Cancer3DPRC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603484   
Orphanet
MedgenPRC1
Genetic Testing Registry PRC1
NextProtO43663 [Medical]
TSGene9055
GENETestsPRC1
Target ValidationPRC1
Huge Navigator PRC1 [HugePedia]
snp3D : Map Gene to Disease9055
BioCentury BCIQPRC1
ClinGenPRC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9055
Chemical/Pharm GKB GenePA33703
Clinical trialPRC1
Miscellaneous
canSAR (ICR)PRC1 (select the gene name)
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRC1
EVEXPRC1
GoPubMedPRC1
iHOPPRC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:26:20 CEST 2017

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