Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PRCP (prolylcarboxypeptidase)

Identity

Alias_namesprolylcarboxypeptidase (angiotensinase C)
Alias_symbol (synonym)PCP
HUMPCP
Other alias
HGNC (Hugo) PRCP
LocusID (NCBI) 5547
Atlas_Id 52116
Location 11q14.1  [Link to chromosome band 11q14]
Location_base_pair Starts at 82822941 and ends at 82901740 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IST1 (16q22.2) / PRCP (11q14.1)PRCP (11q14.1) / CTDSPL (3p22.2)PRCP (11q14.1) / INTS4 (11q14.1)
PRCP (11q14.1) / RAB30 (11q14.1)RAB30 (11q14.1) / PRCP (11q14.1)PRCP 11q14.1 / RAB30 11q14.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRCP   9344
Cards
Entrez_Gene (NCBI)PRCP  5547  prolylcarboxypeptidase
AliasesHUMPCP; PCP
GeneCards (Weizmann)PRCP
Ensembl hg19 (Hinxton)ENSG00000137509 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137509 [Gene_View]  chr11:82822941-82901740 [Contig_View]  PRCP [Vega]
ICGC DataPortalENSG00000137509
TCGA cBioPortalPRCP
AceView (NCBI)PRCP
Genatlas (Paris)PRCP
WikiGenes5547
SOURCE (Princeton)PRCP
Genetics Home Reference (NIH)PRCP
Genomic and cartography
GoldenPath hg38 (UCSC)PRCP  -     chr11:82822941-82901740 -  11q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRCP  -     11q14.1   [Description]    (hg19-Feb_2009)
EnsemblPRCP - 11q14.1 [CytoView hg19]  PRCP - 11q14.1 [CytoView hg38]
Mapping of homologs : NCBIPRCP [Mapview hg19]  PRCP [Mapview hg38]
OMIM176785   
Gene and transcription
Genbank (Entrez)AA477618 AB451270 AB451397 AK090847 AK091786
RefSeq transcript (Entrez)NM_001319214 NM_005040 NM_199418
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRCP
Cluster EST : UnigeneHs.733148 [ NCBI ]
CGAP (NCI)Hs.733148
Alternative Splicing GalleryENSG00000137509
Gene ExpressionPRCP [ NCBI-GEO ]   PRCP [ EBI - ARRAY_EXPRESS ]   PRCP [ SEEK ]   PRCP [ MEM ]
Gene Expression Viewer (FireBrowse)PRCP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5547
GTEX Portal (Tissue expression)PRCP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP42785   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP42785  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP42785
Splice isoforms : SwissVarP42785
Catalytic activity : Enzyme3.4.16.2 [ Enzyme-Expasy ]   3.4.16.23.4.16.2 [ IntEnz-EBI ]   3.4.16.2 [ BRENDA ]   3.4.16.2 [ KEGG ]   
PhosPhoSitePlusP42785
Domains : Interpro (EBI)AB_hydrolase    Peptidase_S28   
Domain families : Pfam (Sanger)Peptidase_S28 (PF05577)   
Domain families : Pfam (NCBI)pfam05577   
Conserved Domain (NCBI)PRCP
DMDM Disease mutations5547
Blocks (Seattle)PRCP
PDB (SRS)3N2Z   
PDB (PDBSum)3N2Z   
PDB (IMB)3N2Z   
PDB (RSDB)3N2Z   
Structural Biology KnowledgeBase3N2Z   
SCOP (Structural Classification of Proteins)3N2Z   
CATH (Classification of proteins structures)3N2Z   
SuperfamilyP42785
Human Protein AtlasENSG00000137509
Peptide AtlasP42785
HPRD08352
IPIIPI00001593   IPI00980998   IPI00399307   IPI00982987   IPI00983229   IPI00982909   IPI00983889   IPI00985278   IPI00976115   IPI00982181   IPI00977609   IPI00981533   
Protein Interaction databases
DIP (DOE-UCLA)P42785
IntAct (EBI)P42785
FunCoupENSG00000137509
BioGRIDPRCP
STRING (EMBL)PRCP
ZODIACPRCP
Ontologies - Pathways
QuickGOP42785
Ontology : AmiGOregulation of thyroid hormone mediated signaling pathway  plasma kallikrein-kinin cascade  negative regulation of systemic arterial blood pressure  serine-type carboxypeptidase activity  protein binding  lysosome  plasma membrane  proteolysis  blood coagulation, intrinsic pathway  azurophil granule membrane  glucose homeostasis  neutrophil degranulation  regulation of blood vessel endothelial cell migration  basal part of cell  angiogenesis involved in wound healing  extracellular exosome  energy homeostasis  ficolin-1-rich granule membrane  regulation of reactive oxygen species metabolic process  
Ontology : EGO-EBIregulation of thyroid hormone mediated signaling pathway  plasma kallikrein-kinin cascade  negative regulation of systemic arterial blood pressure  serine-type carboxypeptidase activity  protein binding  lysosome  plasma membrane  proteolysis  blood coagulation, intrinsic pathway  azurophil granule membrane  glucose homeostasis  neutrophil degranulation  regulation of blood vessel endothelial cell migration  basal part of cell  angiogenesis involved in wound healing  extracellular exosome  energy homeostasis  ficolin-1-rich granule membrane  regulation of reactive oxygen species metabolic process  
Pathways : KEGGProtein digestion and absorption   
NDEx NetworkPRCP
Atlas of Cancer Signalling NetworkPRCP
Wikipedia pathwaysPRCP
Orthology - Evolution
OrthoDB5547
GeneTree (enSembl)ENSG00000137509
Phylogenetic Trees/Animal Genes : TreeFamPRCP
HOVERGENP42785
HOGENOMP42785
Homologs : HomoloGenePRCP
Homology/Alignments : Family Browser (UCSC)PRCP
Gene fusions - Rearrangements
Fusion : MitelmanPRCP/RAB30 [11q14.1/11q14.1]  
Fusion: TCGAPRCP 11q14.1 RAB30 11q14.1 BRCA
Fusion Cancer (Beijing)RAB30 [11q14.1]  -  PRCP [11q14.1]  [FUSC000500]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRCP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRCP
dbVarPRCP
ClinVarPRCP
1000_GenomesPRCP 
Exome Variant ServerPRCP
ExAC (Exome Aggregation Consortium)PRCP (select the gene name)
Genetic variants : HAPMAP5547
Genomic Variants (DGV)PRCP [DGVbeta]
DECIPHERPRCP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRCP 
Mutations
ICGC Data PortalPRCP 
TCGA Data PortalPRCP 
Broad Tumor PortalPRCP
OASIS PortalPRCP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRCP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRCP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRCP
DgiDB (Drug Gene Interaction Database)PRCP
DoCM (Curated mutations)PRCP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRCP (select a term)
intoGenPRCP
Cancer3DPRCP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176785   
Orphanet
MedgenPRCP
Genetic Testing Registry PRCP
NextProtP42785 [Medical]
TSGene5547
GENETestsPRCP
Target ValidationPRCP
Huge Navigator PRCP [HugePedia]
snp3D : Map Gene to Disease5547
BioCentury BCIQPRCP
ClinGenPRCP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5547
Chemical/Pharm GKB GenePA33705
Clinical trialPRCP
Miscellaneous
canSAR (ICR)PRCP (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRCP
EVEXPRCP
GoPubMedPRCP
iHOPPRCP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:50:55 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.