Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PRDM10 (PR/SET domain 10)

Identity

Alias (NCBI)PFM7
TRIS
HGNC (Hugo) PRDM10
HGNC Alias symbKIAA1231
PFM7
MGC131802
HGNC Alias namePRDM zinc finger transcription factor
 PR-domain family member 7
 tristanin
HGNC Previous namePR domain containing 10
 PR domain 10
LocusID (NCBI) 56980
Atlas_Id 41832
Location 11q24.3  [Link to chromosome band 11q24]
Location_base_pair Starts at 129899711 and ends at 129947584 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CITED2 (6q24.1) / PRDM10 (11q24.3)MED12 (Xq13.1) / PRDM10 (11q24.3)PRDM10 (11q24.3) / COL12A1 (6q13)
PRDM10 (11q24.3) / FABP1 (2p11.2)PRDM10 (11q24.3) / PPM1B (2p21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)PRDM10   13995
Cards
Entrez_Gene (NCBI)PRDM10    PR/SET domain 10
AliasesPFM7; TRIS
GeneCards (Weizmann)PRDM10
Ensembl hg19 (Hinxton)ENSG00000170325 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170325 [Gene_View]  ENSG00000170325 [Sequence]  chr11:129899711-129947584 [Contig_View]  PRDM10 [Vega]
ICGC DataPortalENSG00000170325
TCGA cBioPortalPRDM10
AceView (NCBI)PRDM10
Genatlas (Paris)PRDM10
SOURCE (Princeton)PRDM10
Genetics Home Reference (NIH)PRDM10
Genomic and cartography
GoldenPath hg38 (UCSC)PRDM10  -     chr11:129899711-129947584 -  11q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRDM10  -     11q24.3   [Description]    (hg19-Feb_2009)
GoldenPathPRDM10 - 11q24.3 [CytoView hg19]  PRDM10 - 11q24.3 [CytoView hg38]
ImmunoBaseENSG00000170325
Genome Data Viewer NCBIPRDM10 [Mapview hg19]  
OMIM618319   
Gene and transcription
Genbank (Entrez)AB033057 AF275817 AF503171 AK000234 AK310354
RefSeq transcript (Entrez)NM_001367890 NM_001367891 NM_001367892 NM_001367893 NM_001367894 NM_001367895 NM_001367896 NM_001367897 NM_001367898 NM_001367899 NM_020228 NM_199437 NM_199438 NM_199439
Consensus coding sequences : CCDS (NCBI)PRDM10
Gene ExpressionPRDM10 [ NCBI-GEO ]   PRDM10 [ EBI - ARRAY_EXPRESS ]   PRDM10 [ SEEK ]   PRDM10 [ MEM ]
Gene Expression Viewer (FireBrowse)PRDM10 [ Firebrowse - Broad ]
GenevisibleExpression of PRDM10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56980
GTEX Portal (Tissue expression)PRDM10
Human Protein AtlasENSG00000170325-PRDM10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQV6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQV6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQV6
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9NQV6
Domaine pattern : Prosite (Expaxy)SET (PS50280)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)SET_dom    Znf_C2H2_jaz    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)    zf-C2H2_jaz (PF12171)   
Domain families : Pfam (NCBI)pfam00096    pfam12171   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)PRDM10
PDB (RSDB)3IHX   
PDB Europe3IHX   
PDB (PDBSum)3IHX   
PDB (IMB)3IHX   
Structural Biology KnowledgeBase3IHX   
SCOP (Structural Classification of Proteins)3IHX   
CATH (Classification of proteins structures)3IHX   
SuperfamilyQ9NQV6
AlphaFold pdb e-kbQ9NQV6   
Human Protein Atlas [tissue]ENSG00000170325-PRDM10 [tissue]
HPRD11455
Protein Interaction databases
DIP (DOE-UCLA)Q9NQV6
IntAct (EBI)Q9NQV6
BioGRIDPRDM10
STRING (EMBL)PRDM10
ZODIACPRDM10
Ontologies - Pathways
QuickGOQ9NQV6
Ontology : AmiGOchromatin  DNA binding  protein binding  nucleus  methyltransferase activity  regulation of gene expression  transcription repressor complex  methylation  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIchromatin  DNA binding  protein binding  nucleus  methyltransferase activity  regulation of gene expression  transcription repressor complex  methylation  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkPRDM10
Atlas of Cancer Signalling NetworkPRDM10
Wikipedia pathwaysPRDM10
Orthology - Evolution
OrthoDB56980
GeneTree (enSembl)ENSG00000170325
Phylogenetic Trees/Animal Genes : TreeFamPRDM10
Homologs : HomoloGenePRDM10
Homology/Alignments : Family Browser (UCSC)PRDM10
Gene fusions - Rearrangements
Fusion : QuiverPRDM10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRDM10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRDM10
dbVarPRDM10
ClinVarPRDM10
MonarchPRDM10
1000_GenomesPRDM10 
Exome Variant ServerPRDM10
GNOMAD BrowserENSG00000170325
Varsome BrowserPRDM10
ACMGPRDM10 variants
VarityQ9NQV6
Genomic Variants (DGV)PRDM10 [DGVbeta]
DECIPHERPRDM10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRDM10 
Mutations
ICGC Data PortalPRDM10 
TCGA Data PortalPRDM10 
Broad Tumor PortalPRDM10
OASIS PortalPRDM10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRDM10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPRDM10
Mutations and Diseases : HGMDPRDM10
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPRDM10
DgiDB (Drug Gene Interaction Database)PRDM10
DoCM (Curated mutations)PRDM10
CIViC (Clinical Interpretations of Variants in Cancer)PRDM10
Cancer3DPRDM10
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618319   
Orphanet
DisGeNETPRDM10
MedgenPRDM10
Genetic Testing Registry PRDM10
NextProtQ9NQV6 [Medical]
GENETestsPRDM10
Target ValidationPRDM10
Huge Navigator PRDM10 [HugePedia]
ClinGenPRDM10
Clinical trials, drugs, therapy
MyCancerGenomePRDM10
Protein Interactions : CTDPRDM10
Pharm GKB GenePA33708
PharosQ9NQV6
Clinical trialPRDM10
Miscellaneous
canSAR (ICR)PRDM10
HarmonizomePRDM10
DataMed IndexPRDM10
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPRDM10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:26:42 CEST 2021
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.