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PRDM12 (PR/SET domain 12)

Identity

Alias_namesPR domain containing 12
PR domain 12
Other aliasHSAN8
PFM9
HGNC (Hugo) PRDM12
LocusID (NCBI) 59335
Atlas_Id 72193
Location 9q34.12  [Link to chromosome band 9q34]
Location_base_pair Starts at 130664594 and ends at 130682997 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FHIT (3p14.2) / PRDM12 (9q34.12)MLPH (2q37.3) / PRDM12 (9q34.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRDM12   13997
Cards
Entrez_Gene (NCBI)PRDM12  59335  PR/SET domain 12
AliasesHSAN8; PFM9
GeneCards (Weizmann)PRDM12
Ensembl hg19 (Hinxton)ENSG00000130711 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130711 [Gene_View]  chr9:130664594-130682997 [Contig_View]  PRDM12 [Vega]
ICGC DataPortalENSG00000130711
TCGA cBioPortalPRDM12
AceView (NCBI)PRDM12
Genatlas (Paris)PRDM12
WikiGenes59335
SOURCE (Princeton)PRDM12
Genetics Home Reference (NIH)PRDM12
Genomic and cartography
GoldenPath hg38 (UCSC)PRDM12  -     chr9:130664594-130682997 +  9q34.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRDM12  -     9q34.12   [Description]    (hg19-Feb_2009)
EnsemblPRDM12 - 9q34.12 [CytoView hg19]  PRDM12 - 9q34.12 [CytoView hg38]
Mapping of homologs : NCBIPRDM12 [Mapview hg19]  PRDM12 [Mapview hg38]
OMIM616458   616488   
Gene and transcription
Genbank (Entrez)AY004252 BC172255
RefSeq transcript (Entrez)NM_021619
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRDM12
Cluster EST : UnigeneHs.495311 [ NCBI ]
CGAP (NCI)Hs.495311
Alternative Splicing GalleryENSG00000130711
Gene ExpressionPRDM12 [ NCBI-GEO ]   PRDM12 [ EBI - ARRAY_EXPRESS ]   PRDM12 [ SEEK ]   PRDM12 [ MEM ]
Gene Expression Viewer (FireBrowse)PRDM12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)59335
GTEX Portal (Tissue expression)PRDM12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4Q4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4Q4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4Q4
Splice isoforms : SwissVarQ9H4Q4
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   
PhosPhoSitePlusQ9H4Q4
Domaine pattern : Prosite (Expaxy)SET (PS50280)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)SET_dom    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd    Znf_PRDM12   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)SET (SM00317)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)PRDM12
DMDM Disease mutations59335
Blocks (Seattle)PRDM12
PDB (SRS)3EP0   
PDB (PDBSum)3EP0   
PDB (IMB)3EP0   
PDB (RSDB)3EP0   
Structural Biology KnowledgeBase3EP0   
SCOP (Structural Classification of Proteins)3EP0   
CATH (Classification of proteins structures)3EP0   
SuperfamilyQ9H4Q4
Human Protein AtlasENSG00000130711
Peptide AtlasQ9H4Q4
HPRD17900
IPIIPI00024168   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4Q4
IntAct (EBI)Q9H4Q4
FunCoupENSG00000130711
BioGRIDPRDM12
STRING (EMBL)PRDM12
ZODIACPRDM12
Ontologies - Pathways
QuickGOQ9H4Q4
Ontology : AmiGODNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  methyltransferase activity  sensory perception of pain  neuron projection development  methylation  metal ion binding  detection of temperature stimulus involved in sensory perception of pain  positive regulation of histone H3-K9 methylation  positive regulation of histone H3-K9 dimethylation  histone methyltransferase binding  
Ontology : EGO-EBIDNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  methyltransferase activity  sensory perception of pain  neuron projection development  methylation  metal ion binding  detection of temperature stimulus involved in sensory perception of pain  positive regulation of histone H3-K9 methylation  positive regulation of histone H3-K9 dimethylation  histone methyltransferase binding  
NDEx NetworkPRDM12
Atlas of Cancer Signalling NetworkPRDM12
Wikipedia pathwaysPRDM12
Orthology - Evolution
OrthoDB59335
GeneTree (enSembl)ENSG00000130711
Phylogenetic Trees/Animal Genes : TreeFamPRDM12
HOVERGENQ9H4Q4
HOGENOMQ9H4Q4
Homologs : HomoloGenePRDM12
Homology/Alignments : Family Browser (UCSC)PRDM12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRDM12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRDM12
dbVarPRDM12
ClinVarPRDM12
1000_GenomesPRDM12 
Exome Variant ServerPRDM12
ExAC (Exome Aggregation Consortium)PRDM12 (select the gene name)
Genetic variants : HAPMAP59335
Genomic Variants (DGV)PRDM12 [DGVbeta]
DECIPHERPRDM12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRDM12 
Mutations
ICGC Data PortalPRDM12 
TCGA Data PortalPRDM12 
Broad Tumor PortalPRDM12
OASIS PortalPRDM12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRDM12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRDM12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRDM12
DgiDB (Drug Gene Interaction Database)PRDM12
DoCM (Curated mutations)PRDM12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRDM12 (select a term)
intoGenPRDM12
Cancer3DPRDM12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616458    616488   
Orphanet
MedgenPRDM12
Genetic Testing Registry PRDM12
NextProtQ9H4Q4 [Medical]
TSGene59335
GENETestsPRDM12
Target ValidationPRDM12
Huge Navigator PRDM12 [HugePedia]
snp3D : Map Gene to Disease59335
BioCentury BCIQPRDM12
ClinGenPRDM12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD59335
Chemical/Pharm GKB GenePA33710
Clinical trialPRDM12
Miscellaneous
canSAR (ICR)PRDM12 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRDM12
EVEXPRDM12
GoPubMedPRDM12
iHOPPRDM12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:37:16 CEST 2017

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