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PRDM5 (PR domain containing 5)

Identity

Other namesBCS2
PFM2
HGNC (Hugo) PRDM5
LocusID (NCBI) 11107
Location 4q27
Location_base_pair Starts at 121615929 and ends at 121844013 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PRDM5   9349
Cards
Entrez_Gene (NCBI)PRDM5  11107  PR domain containing 5
GeneCards (Weizmann)PRDM5
Ensembl hg19 (Hinxton)ENSG00000138738 [Gene_View]  chr4:121615929-121844013 [Contig_View]  PRDM5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000138738 [Gene_View]  chr4:121615929-121844013 [Contig_View]  PRDM5 [Vega]
ICGC DataPortalENSG00000138738
cBioPortalPRDM5
AceView (NCBI)PRDM5
Genatlas (Paris)PRDM5
WikiGenes11107
SOURCE (Princeton)PRDM5
Genomic and cartography
GoldenPath hg19 (UCSC)PRDM5  -     chr4:121615929-121844013 -  4q27   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PRDM5  -     4q27   [Description]    (hg38-Dec_2013)
EnsemblPRDM5 - 4q27 [CytoView hg19]  PRDM5 - 4q27 [CytoView hg38]
Mapping of homologs : NCBIPRDM5 [Mapview hg19]  PRDM5 [Mapview hg38]
OMIM614161   614170   
Gene and transcription
Genbank (Entrez)AF272897 AK056352 AK310958 AK314293 AW341546
RefSeq transcript (Entrez)NM_001300823 NM_001300824 NM_018699
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NG_031862 NT_016354 NW_001838920 NW_004929320
Consensus coding sequences : CCDS (NCBI)PRDM5
Cluster EST : UnigeneHs.666782 [ NCBI ]
CGAP (NCI)Hs.666782
Alternative Splicing : Fast-db (Paris)GSHG0023498
Alternative Splicing GalleryENSG00000138738
Gene ExpressionPRDM5 [ NCBI-GEO ]     PRDM5 [ SEEK ]   PRDM5 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQX1 (Uniprot)
NextProtQ9NQX1  [Medical]
With graphics : InterProQ9NQX1
Splice isoforms : SwissVarQ9NQX1 (Swissvar)
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)SET (PS50280)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)SET_dom    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd    Znf_C2H2_jaz    Znf_PRDM5   
Related proteins : CluSTrQ9NQX1
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)    zf-C2H2_jaz (PF12171)   
Domain families : Pfam (NCBI)pfam00096    pfam12171   
Domain families : Smart (EMBL)SET (SM00317)  ZnF_C2H2 (SM00355)  
DMDM Disease mutations11107
Blocks (Seattle)Q9NQX1
Human Protein AtlasENSG00000138738
Peptide AtlasQ9NQX1
HPRD17902
IPIIPI00032997   IPI00914659   IPI00744738   IPI00744612   IPI00981059   IPI00968109   IPI00967335   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQX1
IntAct (EBI)Q9NQX1
FunCoupENSG00000138738
BioGRIDPRDM5
IntegromeDBPRDM5
STRING (EMBL)PRDM5
Ontologies - Pathways
QuickGOQ9NQX1
Ontology : AmiGOmitotic cell cycle  transcription regulatory region sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  methyltransferase activity  histone deacetylation  sequence-specific DNA binding  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  metal ion binding  histone H3-K9 methylation  repressing transcription factor binding  
Ontology : EGO-EBImitotic cell cycle  transcription regulatory region sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  methyltransferase activity  histone deacetylation  sequence-specific DNA binding  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  metal ion binding  histone H3-K9 methylation  repressing transcription factor binding  
Protein Interaction DatabasePRDM5
DoCM (Curated mutations)PRDM5
Wikipedia pathwaysPRDM5
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerPRDM5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRDM5
dbVarPRDM5
ClinVarPRDM5
1000_GenomesPRDM5 
Exome Variant ServerPRDM5
SNP (GeneSNP Utah)PRDM5
SNP : HGBasePRDM5
Genetic variants : HAPMAPPRDM5
Genomic VariantsPRDM5  PRDM5 [DGVbeta]
Mutations
ICGC Data PortalENSG00000138738 
Somatic Mutations in Cancer : COSMICPRDM5 
CONAN: Copy Number AnalysisPRDM5 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)4:121615929-121844013
Mutations and Diseases : HGMDPRDM5
OMIM614161    614170   
MedgenPRDM5
NextProtQ9NQX1 [Medical]
GENETestsPRDM5
Disease Genetic AssociationPRDM5
Huge Navigator PRDM5 [HugePedia]  PRDM5 [HugeCancerGEM]
snp3D : Map Gene to Disease11107
DGIdb (Drug Gene Interaction db)PRDM5
General knowledge
Homologs : HomoloGenePRDM5
Homology/Alignments : Family Browser (UCSC)PRDM5
Phylogenetic Trees/Animal Genes : TreeFamPRDM5
Chemical/Protein Interactions : CTD11107
Chemical/Pharm GKB GenePA33717
Clinical trialPRDM5
Cancer Resource (Charite)ENSG00000138738
Other databases
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
CoreMinePRDM5
GoPubMedPRDM5
iHOPPRDM5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 00:57:35 CET 2014

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