PRELID1 (PRELI domain containing 1)

2018-11-01  

Identity

HGNC
PRELID1
LOCATION
5q35.3
LOCUSID
27166
ALIAS
CGI-106,PRELI,PX19,SBBI12
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 27166
MIM: 605733
HGNC: 30255
Ensembl: ENSG00000169230

Variants:

dbSNP: 27166
ClinVar: 27166
TCGA: ENSG00000169230
COSMIC: PRELID1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169230ENST00000303204Q9Y255
ENSG00000169230ENST00000503216Q9Y255
ENSG00000169230ENST00000503853H0YA79
ENSG00000169230ENST00000504594D6REW1
ENSG00000169230ENST00000510797D6RC47

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
TP53 Regulates Transcription of Cell Death GenesREACTOMER-HSA-5633008
TP53 Regulates Transcription of Genes Involved in Cytochrome C ReleaseREACTOMER-HSA-6803204

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil

References

Pubmed IDYearTitleCitations
239317592013TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid.53
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
213646292010Vital function of PRELI and essential requirement of its LEA motif.8
308506072019Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins.3
262756932015Effects of PRELI in Oxidative-Stressed HepG2 Cells.2
289121682017Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes.2
226664212012Spare PRELI gene loci: failsafe chromosome insurance?0

Citation

Dessen P

PRELID1 (PRELI domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57707/prelid1