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PRELP (proline and arginine rich end leucine rich repeat protein)

Identity

Alias_namesproline arginine-rich end leucine-rich repeat protein
Alias_symbol (synonym)SLRR2A
prolargin
Other aliasMST161
MSTP161
HGNC (Hugo) PRELP
LocusID (NCBI) 5549
Atlas_Id 53811
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 203475755 and ends at 203491351 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CCDC36 (3p21.31) / PRELP (1q32.1)CHD4 (12p13.31) / PRELP (1q32.1)LIPA (10q23.31) / PRELP (1q32.1)
NFASC (1q32.1) / PRELP (1q32.1)PRELP (1q32.1) / CCDC36 (3p21.31)PRELP (1q32.1) / LOC100507412 (-)
NFASC 1q32.1 / PRELP 1q32.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRELP   9357
Cards
Entrez_Gene (NCBI)PRELP  5549  proline and arginine rich end leucine rich repeat protein
AliasesMST161; MSTP161; SLRR2A
GeneCards (Weizmann)PRELP
Ensembl hg19 (Hinxton)ENSG00000188783 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188783 [Gene_View]  chr1:203475755-203491351 [Contig_View]  PRELP [Vega]
ICGC DataPortalENSG00000188783
TCGA cBioPortalPRELP
AceView (NCBI)PRELP
Genatlas (Paris)PRELP
WikiGenes5549
SOURCE (Princeton)PRELP
Genetics Home Reference (NIH)PRELP
Genomic and cartography
GoldenPath hg38 (UCSC)PRELP  -     chr1:203475755-203491351 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRELP  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblPRELP - 1q32.1 [CytoView hg19]  PRELP - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIPRELP [Mapview hg19]  PRELP [Mapview hg38]
OMIM601914   
Gene and transcription
Genbank (Entrez)AK098245 BC032498 BE275567 BG569381 BI770477
RefSeq transcript (Entrez)NM_002725 NM_201348
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRELP
Cluster EST : UnigeneHs.632481 [ NCBI ]
CGAP (NCI)Hs.632481
Alternative Splicing GalleryENSG00000188783
Gene ExpressionPRELP [ NCBI-GEO ]   PRELP [ EBI - ARRAY_EXPRESS ]   PRELP [ SEEK ]   PRELP [ MEM ]
Gene Expression Viewer (FireBrowse)PRELP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5549
GTEX Portal (Tissue expression)PRELP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51888   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51888  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51888
Splice isoforms : SwissVarP51888
PhosPhoSitePlusP51888
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT    Prolargin   
Domain families : Pfam (Sanger)LRR_1 (PF00560)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam00560    pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)PRELP
DMDM Disease mutations5549
Blocks (Seattle)PRELP
SuperfamilyP51888
Human Protein AtlasENSG00000188783
Peptide AtlasP51888
HPRD03556
IPIIPI00020987   IPI00980755   
Protein Interaction databases
DIP (DOE-UCLA)P51888
IntAct (EBI)P51888
FunCoupENSG00000188783
BioGRIDPRELP
STRING (EMBL)PRELP
ZODIACPRELP
Ontologies - Pathways
QuickGOP51888
Ontology : AmiGOskeletal system development  extracellular matrix structural constituent  extracellular region  proteinaceous extracellular matrix  extracellular space  Golgi lumen  axonogenesis  cell aging  heparin binding  keratan sulfate biosynthetic process  extracellular matrix  extracellular matrix  keratan sulfate catabolic process  lysosomal lumen  extracellular exosome  extracellular vesicle  
Ontology : EGO-EBIskeletal system development  extracellular matrix structural constituent  extracellular region  proteinaceous extracellular matrix  extracellular space  Golgi lumen  axonogenesis  cell aging  heparin binding  keratan sulfate biosynthetic process  extracellular matrix  extracellular matrix  keratan sulfate catabolic process  lysosomal lumen  extracellular exosome  extracellular vesicle  
NDEx NetworkPRELP
Atlas of Cancer Signalling NetworkPRELP
Wikipedia pathwaysPRELP
Orthology - Evolution
OrthoDB5549
GeneTree (enSembl)ENSG00000188783
Phylogenetic Trees/Animal Genes : TreeFamPRELP
HOVERGENP51888
HOGENOMP51888
Homologs : HomoloGenePRELP
Homology/Alignments : Family Browser (UCSC)PRELP
Gene fusions - Rearrangements
Fusion : MitelmanNFASC/PRELP [1q32.1/1q32.1]  [t(1;1)(q32;q32)]  
Fusion: TCGANFASC 1q32.1 PRELP 1q32.1 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRELP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRELP
dbVarPRELP
ClinVarPRELP
1000_GenomesPRELP 
Exome Variant ServerPRELP
ExAC (Exome Aggregation Consortium)PRELP (select the gene name)
Genetic variants : HAPMAP5549
Genomic Variants (DGV)PRELP [DGVbeta]
DECIPHERPRELP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRELP 
Mutations
ICGC Data PortalPRELP 
TCGA Data PortalPRELP 
Broad Tumor PortalPRELP
OASIS PortalPRELP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRELP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRELP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRELP
DgiDB (Drug Gene Interaction Database)PRELP
DoCM (Curated mutations)PRELP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRELP (select a term)
intoGenPRELP
Cancer3DPRELP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601914   
Orphanet
MedgenPRELP
Genetic Testing Registry PRELP
NextProtP51888 [Medical]
TSGene5549
GENETestsPRELP
Target ValidationPRELP
Huge Navigator PRELP [HugePedia]
snp3D : Map Gene to Disease5549
BioCentury BCIQPRELP
ClinGenPRELP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5549
Chemical/Pharm GKB GenePA33729
Clinical trialPRELP
Miscellaneous
canSAR (ICR)PRELP (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRELP
EVEXPRELP
GoPubMedPRELP
iHOPPRELP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:26:23 CEST 2017

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