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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

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PRG3 (proteoglycan 3)

Identity

Other namesMBP2
MBPH
HGNC (Hugo) PRG3
LocusID (NCBI) 10394
Location 11q12.1
Location_base_pair Starts at 57144242 and ends at 57148623 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PRG3   9363
Cards
Entrez_Gene (NCBI)PRG3  10394  proteoglycan 3
GeneCards (Weizmann)PRG3
Ensembl hg19 (Hinxton)ENSG00000156575 [Gene_View]  chr11:57144242-57148623 [Contig_View]  PRG3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000156575 [Gene_View]  chr11:57144242-57148623 [Contig_View]  PRG3 [Vega]
ICGC DataPortalENSG00000156575
cBioPortalPRG3
AceView (NCBI)PRG3
Genatlas (Paris)PRG3
WikiGenes10394
SOURCE (Princeton)PRG3
Genomic and cartography
GoldenPath hg19 (UCSC)PRG3  -     chr11:57144242-57148623 -  11q12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PRG3  -     11q12.1   [Description]    (hg38-Dec_2013)
EnsemblPRG3 - 11q12.1 [CytoView hg19]  PRG3 - 11q12.1 [CytoView hg38]
Mapping of homologs : NCBIPRG3 [Mapview hg19]  PRG3 [Mapview hg38]
OMIM606814   
Gene and transcription
Genbank (Entrez)AF132209 AY358930 BC069126 BC101613 BC113411
RefSeq transcript (Entrez)NM_006093
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NT_167190 NW_001838023 NW_004929380
Consensus coding sequences : CCDS (NCBI)PRG3
Cluster EST : UnigeneHs.251386 [ NCBI ]
CGAP (NCI)Hs.251386
Alternative Splicing : Fast-db (Paris)GSHG0005776
Alternative Splicing GalleryENSG00000156575
Gene ExpressionPRG3 [ NCBI-GEO ]     PRG3 [ SEEK ]   PRG3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2Y8 (Uniprot)
NextProtQ9Y2Y8  [Medical]
With graphics : InterProQ9Y2Y8
Splice isoforms : SwissVarQ9Y2Y8 (Swissvar)
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_1 (PS00615)    C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin    C-type_lectin-like    C-type_lectin_CS    C-type_lectin_fold    Eosinophil_major_basic   
Related proteins : CluSTrQ9Y2Y8
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
DMDM Disease mutations10394
Blocks (Seattle)Q9Y2Y8
Human Protein AtlasENSG00000156575
Peptide AtlasQ9Y2Y8
HPRD08434
IPIIPI00005778   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2Y8
IntAct (EBI)Q9Y2Y8
FunCoupENSG00000156575
BioGRIDPRG3
IntegromeDBPRG3
STRING (EMBL)PRG3
Ontologies - Pathways
QuickGOQ9Y2Y8
Ontology : AmiGOhistamine biosynthetic process  immune response  negative regulation of translation  leukotriene biosynthetic process  carbohydrate binding  neutrophil activation  superoxide anion generation  positive regulation of interleukin-8 biosynthetic process  basophil activation  
Ontology : EGO-EBIhistamine biosynthetic process  immune response  negative regulation of translation  leukotriene biosynthetic process  carbohydrate binding  neutrophil activation  superoxide anion generation  positive regulation of interleukin-8 biosynthetic process  basophil activation  
Protein Interaction DatabasePRG3
DoCM (Curated mutations)PRG3
Wikipedia pathwaysPRG3
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerPRG3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRG3
dbVarPRG3
ClinVarPRG3
1000_GenomesPRG3 
Exome Variant ServerPRG3
SNP (GeneSNP Utah)PRG3
SNP : HGBasePRG3
Genetic variants : HAPMAPPRG3
Genomic Variants (DGV)PRG3 [DGVbeta]
Mutations
ICGC Data PortalENSG00000156575 
Somatic Mutations in Cancer : COSMICPRG3 
CONAN: Copy Number AnalysisPRG3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)11:57144242-57148623
Mutations and Diseases : HGMDPRG3
OMIM606814   
MedgenPRG3
NextProtQ9Y2Y8 [Medical]
GENETestsPRG3
Disease Genetic AssociationPRG3
Huge Navigator PRG3 [HugePedia]  PRG3 [HugeCancerGEM]
snp3D : Map Gene to Disease10394
DGIdb (Drug Gene Interaction db)PRG3
General knowledge
Homologs : HomoloGenePRG3
Homology/Alignments : Family Browser (UCSC)PRG3
Phylogenetic Trees/Animal Genes : TreeFamPRG3
Chemical/Protein Interactions : CTD10394
Chemical/Pharm GKB GenePA33735
Clinical trialPRG3
Cancer Resource (Charite)ENSG00000156575
Other databases
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
CoreMinePRG3
GoPubMedPRG3
iHOPPRG3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 18:07:13 CET 2015

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