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PRICKLE1 (prickle homolog 1 (Drosophila))

Identity

Other namesEPM1B
RILP
HGNC (Hugo) PRICKLE1
LocusID (NCBI) 144165
Location 12q12
Location_base_pair Starts at 42852140 and ends at 42877416 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PRICKLE1   17019
Cards
Entrez_Gene (NCBI)PRICKLE1  144165  prickle homolog 1 (Drosophila)
GeneCards (Weizmann)PRICKLE1
Ensembl (Hinxton)ENSG00000139174 [Gene_View]  chr12:42852140-42877416 [Contig_View]  PRICKLE1 [Vega]
ICGC DataPortalENSG00000139174
cBioPortalPRICKLE1
AceView (NCBI)PRICKLE1
Genatlas (Paris)PRICKLE1
WikiGenes144165
SOURCE (Princeton)NM_001144881 NM_001144882 NM_001144883 NM_153026
Genomic and cartography
GoldenPath (UCSC)PRICKLE1  -  12q12   chr12:42852140-42877416 -  12q12   [Description]    (hg19-Feb_2009)
EnsemblPRICKLE1 - 12q12 [CytoView]
Mapping of homologs : NCBIPRICKLE1 [Mapview]
OMIM608500   612437   
Gene and transcription
Genbank (Entrez)AF399844 AF543759 AF543760 AK056189 AK056499
RefSeq transcript (Entrez)NM_001144881 NM_001144882 NM_001144883 NM_153026
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_012965 NT_029419 NW_001838057 NW_004929384
Consensus coding sequences : CCDS (NCBI)PRICKLE1
Cluster EST : UnigeneHs.720221 [ NCBI ]
CGAP (NCI)Hs.720221
Alternative Splicing : Fast-db (Paris)GSHG0007384
Alternative Splicing GalleryENSG00000139174
Gene ExpressionPRICKLE1 [ NCBI-GEO ]     PRICKLE1 [ SEEK ]   PRICKLE1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96MT3 (Uniprot)
NextProtQ96MT3  [Medical]
With graphics : InterProQ96MT3
Splice isoforms : SwissVarQ96MT3 (Swissvar)
Domaine pattern : Prosite (Expaxy)LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)    PET (PS51303)   
Domains : Interpro (EBI)PET_domain [organisation]   Znf_LIM [organisation]  
Related proteins : CluSTrQ96MT3
Domain families : Pfam (Sanger)LIM (PF00412)    PET (PF06297)   
Domain families : Pfam (NCBI)pfam00412    pfam06297   
Domain families : Smart (EMBL)LIM (SM00132)  
DMDM Disease mutations144165
Blocks (Seattle)Q96MT3
Human Protein AtlasENSG00000139174 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ96MT3
HPRD16341
IPIIPI00043363   IPI01021615   IPI01021774   IPI01021308   
Protein Interaction databases
DIP (DOE-UCLA)Q96MT3
IntAct (EBI)Q96MT3
FunCoupENSG00000139174
BioGRIDPRICKLE1
InParanoidQ96MT3
Interologous Interaction database Q96MT3
IntegromeDBPRICKLE1
STRING (EMBL)PRICKLE1
Ontologies - Pathways
Ontology : AmiGOneural tube closure  protein binding  nucleus  cytosol  cytosol  protein import into nucleus  protein import into nucleus  zinc ion binding  positive regulation of protein ubiquitination  nuclear membrane  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  negative regulation of transcription, DNA-templated  negative regulation of canonical Wnt signaling pathway  negative regulation of cardiac muscle cell myoblast differentiation  
Ontology : EGO-EBIneural tube closure  protein binding  nucleus  cytosol  cytosol  protein import into nucleus  protein import into nucleus  zinc ion binding  positive regulation of protein ubiquitination  nuclear membrane  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  negative regulation of transcription, DNA-templated  negative regulation of canonical Wnt signaling pathway  negative regulation of cardiac muscle cell myoblast differentiation  
Pathways : KEGGWnt signaling pathway   
Protein Interaction DatabasePRICKLE1
Wikipedia pathwaysPRICKLE1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PRICKLE1
snp3D : Map Gene to Disease144165
SNP (GeneSNP Utah)PRICKLE1
SNP : HGBasePRICKLE1
Genetic variants : HAPMAPPRICKLE1
Exome VariantPRICKLE1
1000_GenomesPRICKLE1 
ICGC programENSG00000139174 
Somatic Mutations in Cancer : COSMICPRICKLE1 
CONAN: Copy Number AnalysisPRICKLE1 
Mutations and Diseases : HGMDPRICKLE1
Mutations and Diseases : intOGenPRICKLE1
Genomic VariantsPRICKLE1  PRICKLE1 [DGVbeta]
dbVarPRICKLE1
ClinVarPRICKLE1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM608500    612437   
MedgenPRICKLE1
GENETestsPRICKLE1
Disease Genetic AssociationPRICKLE1
Huge Navigator PRICKLE1 [HugePedia]  PRICKLE1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGenePRICKLE1
Homology/Alignments : Family Browser (UCSC)PRICKLE1
Phylogenetic Trees/Animal Genes : TreeFamPRICKLE1
Chemical/Protein Interactions : CTD144165
Chemical/Pharm GKB GenePA134906946
Clinical trialPRICKLE1
Cancer Resource (Charite)ENSG00000139174
Other databases
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
CoreMinePRICKLE1
iHOPPRICKLE1
OncoSearchPRICKLE1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 19:12:37 CEST 2014

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