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PRICKLE4 (prickle planar cell polarity protein 4)

Identity

Alias_namesC6orf49
chromosome 6 open reading frame 49
prickle homolog 4 (Drosophila)
Alias_symbol (synonym)OEBT
DKFZp761H221
Other aliasOBTP
TOMM6
HGNC (Hugo) PRICKLE4
LocusID (NCBI) 29964
Atlas_Id 892
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41780762 and ends at 41787372 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PRICKLE4 (6p21.1) / GAPDH (12p13.31)PRICKLE4 (6p21.1) / LDB1 (10q24.32)PRICKLE4 (6p21.1) / PRICKLE4 (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRICKLE4   16805
Cards
Entrez_Gene (NCBI)PRICKLE4  29964  prickle planar cell polarity protein 4
AliasesC6orf49; OBTP; OEBT; TOMM6
GeneCards (Weizmann)PRICKLE4
Ensembl hg19 (Hinxton)ENSG00000124593 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124593 [Gene_View]  ENSG00000124593 [Sequence]  chr6:41780762-41787372 [Contig_View]  PRICKLE4 [Vega]
ICGC DataPortalENSG00000124593
TCGA cBioPortalPRICKLE4
AceView (NCBI)PRICKLE4
Genatlas (Paris)PRICKLE4
WikiGenes29964
SOURCE (Princeton)PRICKLE4
Genetics Home Reference (NIH)PRICKLE4
Genomic and cartography
GoldenPath hg38 (UCSC)PRICKLE4  -     chr6:41780762-41787372 +  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRICKLE4  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblPRICKLE4 - 6p21.1 [CytoView hg19]  PRICKLE4 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIPRICKLE4 [Mapview hg19]  PRICKLE4 [Mapview hg38]
OMIM611389   
Gene and transcription
Genbank (Entrez)BC110458 BC110459 DA875485 DA917216 DA957684
RefSeq transcript (Entrez)NM_013397
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRICKLE4
Cluster EST : UnigeneHs.715653 [ NCBI ]
CGAP (NCI)Hs.715653
Alternative Splicing GalleryENSG00000124593
Gene ExpressionPRICKLE4 [ NCBI-GEO ]   PRICKLE4 [ EBI - ARRAY_EXPRESS ]   PRICKLE4 [ SEEK ]   PRICKLE4 [ MEM ]
Gene Expression Viewer (FireBrowse)PRICKLE4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29964
GTEX Portal (Tissue expression)PRICKLE4
Human Protein AtlasENSG00000124593-PRICKLE4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2TBC4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2TBC4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2TBC4
Splice isoforms : SwissVarQ2TBC4
PhosPhoSitePlusQ2TBC4
Domaine pattern : Prosite (Expaxy)LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)    PET (PS51303)   
Domains : Interpro (EBI)PET_domain    Znf_LIM   
Domain families : Pfam (Sanger)LIM (PF00412)    PET (PF06297)   
Domain families : Pfam (NCBI)pfam00412    pfam06297   
Domain families : Smart (EMBL)LIM (SM00132)  
Conserved Domain (NCBI)PRICKLE4
DMDM Disease mutations29964
Blocks (Seattle)PRICKLE4
SuperfamilyQ2TBC4
Human Protein Atlas [tissue]ENSG00000124593-PRICKLE4 [tissue]
Peptide AtlasQ2TBC4
HPRD12884
IPIIPI00853239   IPI00793856   IPI00718855   
Protein Interaction databases
DIP (DOE-UCLA)Q2TBC4
IntAct (EBI)Q2TBC4
FunCoupENSG00000124593
BioGRIDPRICKLE4
STRING (EMBL)PRICKLE4
ZODIACPRICKLE4
Ontologies - Pathways
QuickGOQ2TBC4
Ontology : AmiGOmolecular_function  nucleus  biological_process  zinc ion binding  
Ontology : EGO-EBImolecular_function  nucleus  biological_process  zinc ion binding  
NDEx NetworkPRICKLE4
Atlas of Cancer Signalling NetworkPRICKLE4
Wikipedia pathwaysPRICKLE4
Orthology - Evolution
OrthoDB29964
GeneTree (enSembl)ENSG00000124593
Phylogenetic Trees/Animal Genes : TreeFamPRICKLE4
HOVERGENQ2TBC4
HOGENOMQ2TBC4
Homologs : HomoloGenePRICKLE4
Homology/Alignments : Family Browser (UCSC)PRICKLE4
Gene fusions - Rearrangements
Fusion : QuiverPRICKLE4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRICKLE4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRICKLE4
dbVarPRICKLE4
ClinVarPRICKLE4
1000_GenomesPRICKLE4 
Exome Variant ServerPRICKLE4
ExAC (Exome Aggregation Consortium)ENSG00000124593
GNOMAD BrowserENSG00000124593
Genetic variants : HAPMAP29964
Genomic Variants (DGV)PRICKLE4 [DGVbeta]
DECIPHERPRICKLE4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRICKLE4 
Mutations
ICGC Data PortalPRICKLE4 
TCGA Data PortalPRICKLE4 
Broad Tumor PortalPRICKLE4
OASIS PortalPRICKLE4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRICKLE4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRICKLE4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRICKLE4
DgiDB (Drug Gene Interaction Database)PRICKLE4
DoCM (Curated mutations)PRICKLE4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRICKLE4 (select a term)
intoGenPRICKLE4
Cancer3DPRICKLE4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611389   
Orphanet
DisGeNETPRICKLE4
MedgenPRICKLE4
Genetic Testing Registry PRICKLE4
NextProtQ2TBC4 [Medical]
TSGene29964
GENETestsPRICKLE4
Target ValidationPRICKLE4
Huge Navigator PRICKLE4 [HugePedia]
snp3D : Map Gene to Disease29964
BioCentury BCIQPRICKLE4
ClinGenPRICKLE4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29964
Chemical/Pharm GKB GenePA162400083
Clinical trialPRICKLE4
Miscellaneous
canSAR (ICR)PRICKLE4 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRICKLE4
EVEXPRICKLE4
GoPubMedPRICKLE4
iHOPPRICKLE4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:44:41 CEST 2018

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