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PRIMPOL (primase and DNA directed polymerase)

Identity

Other aliasCCDC111
MYP22
Primpol1
HGNC (Hugo) PRIMPOL
LocusID (NCBI) 201973
Atlas_Id 57026
Location 4q35.1  [Link to chromosome band 4q35]
Location_base_pair Starts at 184649613 and ends at 184694959 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PRIMPOL (4q35.1) / PRIMPOL (4q35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRIMPOL   26575
Cards
Entrez_Gene (NCBI)PRIMPOL  201973  primase and DNA directed polymerase
AliasesCCDC111; MYP22; Primpol1
GeneCards (Weizmann)PRIMPOL
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr4:184649613-184694959 [Contig_View]  PRIMPOL [Vega]
TCGA cBioPortalPRIMPOL
AceView (NCBI)PRIMPOL
Genatlas (Paris)PRIMPOL
WikiGenes201973
SOURCE (Princeton)PRIMPOL
Genetics Home Reference (NIH)PRIMPOL
Genomic and cartography
GoldenPath hg38 (UCSC)PRIMPOL  -     chr4:184649613-184694959 +  4q35.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRIMPOL  -     4q35.1   [Description]    (hg19-Feb_2009)
EnsemblPRIMPOL - 4q35.1 [CytoView hg19]  PRIMPOL - 4q35.1 [CytoView hg38]
Mapping of homologs : NCBIPRIMPOL [Mapview hg19]  PRIMPOL [Mapview hg38]
OMIM615420   615421   
Gene and transcription
Genbank (Entrez)AK057729 AK307317 BC018930 BC047467 BC064600
RefSeq transcript (Entrez)NM_001300767 NM_001300768 NM_001345891 NM_001345892 NM_001345893 NM_001345894 NM_001345895 NM_001345896 NM_001345897 NM_001345898 NM_001345899 NM_001345900 NM_001345901 NM_152683
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRIMPOL
Cluster EST : UnigeneHs.481307 [ NCBI ]
CGAP (NCI)Hs.481307
Gene ExpressionPRIMPOL [ NCBI-GEO ]   PRIMPOL [ EBI - ARRAY_EXPRESS ]   PRIMPOL [ SEEK ]   PRIMPOL [ MEM ]
Gene Expression Viewer (FireBrowse)PRIMPOL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)201973
GTEX Portal (Tissue expression)PRIMPOL
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96LW4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96LW4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96LW4
Splice isoforms : SwissVarQ96LW4
Catalytic activity : Enzyme2.7.7.- [ Enzyme-Expasy ]   2.7.7.-2.7.7.- [ IntEnz-EBI ]   2.7.7.- [ BRENDA ]   2.7.7.- [ KEGG ]   
PhosPhoSitePlusQ96LW4
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PRIMPOL
DMDM Disease mutations201973
Blocks (Seattle)PRIMPOL
PDB (SRS)5L2X   
PDB (PDBSum)5L2X   
PDB (IMB)5L2X   
PDB (RSDB)5L2X   
Structural Biology KnowledgeBase5L2X   
SCOP (Structural Classification of Proteins)5L2X   
CATH (Classification of proteins structures)5L2X   
SuperfamilyQ96LW4
Peptide AtlasQ96LW4
IPIIPI00065356   IPI00965375   IPI00966884   IPI00963936   IPI00966588   IPI00965627   
Protein Interaction databases
DIP (DOE-UCLA)Q96LW4
IntAct (EBI)Q96LW4
BioGRIDPRIMPOL
STRING (EMBL)PRIMPOL
ZODIACPRIMPOL
Ontologies - Pathways
QuickGOQ96LW4
Ontology : AmiGOchromatin binding  DNA-directed DNA polymerase activity  DNA primase activity  protein binding  nucleus  mitochondrial matrix  mitochondrial DNA replication  DNA replication, synthesis of RNA primer  response to UV  translesion synthesis  manganese ion binding  replication fork processing  
Ontology : EGO-EBIchromatin binding  DNA-directed DNA polymerase activity  DNA primase activity  protein binding  nucleus  mitochondrial matrix  mitochondrial DNA replication  DNA replication, synthesis of RNA primer  response to UV  translesion synthesis  manganese ion binding  replication fork processing  
NDEx NetworkPRIMPOL
Atlas of Cancer Signalling NetworkPRIMPOL
Wikipedia pathwaysPRIMPOL
Orthology - Evolution
OrthoDB201973
Phylogenetic Trees/Animal Genes : TreeFamPRIMPOL
HOVERGENQ96LW4
HOGENOMQ96LW4
Homologs : HomoloGenePRIMPOL
Homology/Alignments : Family Browser (UCSC)PRIMPOL
Gene fusions - Rearrangements
Fusion: Tumor Portal PRIMPOL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRIMPOL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRIMPOL
dbVarPRIMPOL
ClinVarPRIMPOL
1000_GenomesPRIMPOL 
Exome Variant ServerPRIMPOL
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP201973
Genomic Variants (DGV)PRIMPOL [DGVbeta]
DECIPHERPRIMPOL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRIMPOL 
Mutations
ICGC Data PortalPRIMPOL 
TCGA Data PortalPRIMPOL 
Broad Tumor PortalPRIMPOL
OASIS PortalPRIMPOL [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPRIMPOL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRIMPOL
DgiDB (Drug Gene Interaction Database)PRIMPOL
DoCM (Curated mutations)PRIMPOL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRIMPOL (select a term)
intoGenPRIMPOL
Cancer3DPRIMPOL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615420    615421   
Orphanet
MedgenPRIMPOL
Genetic Testing Registry PRIMPOL
NextProtQ96LW4 [Medical]
TSGene201973
GENETestsPRIMPOL
Target ValidationPRIMPOL
Huge Navigator PRIMPOL [HugePedia]
snp3D : Map Gene to Disease201973
BioCentury BCIQPRIMPOL
ClinGenPRIMPOL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD201973
Chemical/Pharm GKB GenePA145008751
Clinical trialPRIMPOL
Miscellaneous
canSAR (ICR)PRIMPOL (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRIMPOL
EVEXPRIMPOL
GoPubMedPRIMPOL
iHOPPRIMPOL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 13:06:35 CET 2017

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