Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PRKACG (protein kinase cAMP-activated catalytic subunit gamma)

Identity

Alias_namesprotein kinase, cAMP-dependent, catalytic, gamma
protein kinase, cAMP-dependent, gamma catalytic subunit
Alias_symbol (synonym)PKACg
Other aliasBDPLT19
KAPG
HGNC (Hugo) PRKACG
LocusID (NCBI) 5568
Atlas_Id 41848
Location 9q21.11  [Link to chromosome band 9q21]
Location_base_pair Starts at 71627449 and ends at 71629039 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRKACG   9382
Cards
Entrez_Gene (NCBI)PRKACG  5568  protein kinase cAMP-activated catalytic subunit gamma
AliasesBDPLT19; KAPG; PKACg
GeneCards (Weizmann)PRKACG
Ensembl hg19 (Hinxton)ENSG00000165059 [Gene_View]  chr9:71627449-71629039 [Contig_View]  PRKACG [Vega]
Ensembl hg38 (Hinxton)ENSG00000165059 [Gene_View]  chr9:71627449-71629039 [Contig_View]  PRKACG [Vega]
ICGC DataPortalENSG00000165059
TCGA cBioPortalPRKACG
AceView (NCBI)PRKACG
Genatlas (Paris)PRKACG
WikiGenes5568
SOURCE (Princeton)PRKACG
Genetics Home Reference (NIH)PRKACG
Genomic and cartography
GoldenPath hg19 (UCSC)PRKACG  -     chr9:71627449-71629039 -  9q21.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PRKACG  -     9q21.11   [Description]    (hg38-Dec_2013)
EnsemblPRKACG - 9q21.11 [CytoView hg19]  PRKACG - 9q21.11 [CytoView hg38]
Mapping of homologs : NCBIPRKACG [Mapview hg19]  PRKACG [Mapview hg38]
OMIM176893   616176   
Gene and transcription
Genbank (Entrez)BC039888 DQ890764 DQ893927
RefSeq transcript (Entrez)NM_002732
RefSeq genomic (Entrez)NC_000009 NC_018920 NG_042177 NT_008470 NW_004929366
Consensus coding sequences : CCDS (NCBI)PRKACG
Cluster EST : UnigeneHs.158029 [ NCBI ]
CGAP (NCI)Hs.158029
Alternative Splicing GalleryENSG00000165059
Gene ExpressionPRKACG [ NCBI-GEO ]   PRKACG [ EBI - ARRAY_EXPRESS ]   PRKACG [ SEEK ]   PRKACG [ MEM ]
Gene Expression Viewer (FireBrowse)PRKACG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5568
GTEX Portal (Tissue expression)PRKACG
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22612   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP22612  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP22612
Splice isoforms : SwissVarP22612
PhosPhoSitePlusP22612
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)AGC-kinase_C    Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TK_X (SM00133)  S_TKc (SM00220)  
Conserved Domain (NCBI)PRKACG
DMDM Disease mutations5568
Blocks (Seattle)PRKACG
SuperfamilyP22612
Human Protein AtlasENSG00000165059
Peptide AtlasP22612
HPRD01483
IPIIPI00219592   
Protein Interaction databases
DIP (DOE-UCLA)P22612
IntAct (EBI)P22612
FunCoupENSG00000165059
BioGRIDPRKACG
STRING (EMBL)PRKACG
ZODIACPRKACG
Ontologies - Pathways
QuickGOP22612
Ontology : AmiGOstimulatory C-type lectin receptor signaling pathway  renal water homeostasis  protein serine/threonine kinase activity  protein serine/threonine kinase activity  cAMP-dependent protein kinase activity  ATP binding  nucleoplasm  cytosol  protein phosphorylation  spermatogenesis  blood coagulation  male gonad development  activation of protein kinase A activity  lipoprotein metabolic process  cellular response to glucagon stimulus  ciliary base  
Ontology : EGO-EBIstimulatory C-type lectin receptor signaling pathway  renal water homeostasis  protein serine/threonine kinase activity  protein serine/threonine kinase activity  cAMP-dependent protein kinase activity  ATP binding  nucleoplasm  cytosol  protein phosphorylation  spermatogenesis  blood coagulation  male gonad development  activation of protein kinase A activity  lipoprotein metabolic process  cellular response to glucagon stimulus  ciliary base  
Pathways : BIOCARTASonic Hedgehog (Shh) Pathway [Genes]    Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor [Genes]    Regulation of ck1/cdk5 by type 1 glutamate receptors [Genes]    Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation [Genes]    Nitric Oxide Signaling Pathway [Genes]    GATA3 participate in activating the Th2 cytokine genes expression [Genes]    Repression of Pain Sensation by the Transcriptional Regulator DREAM [Genes]    mCalpain and friends in Cell motility [Genes]    Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells [Genes]    Transcription Regulation by Methyltransferase of CARM1 [Genes]    NFAT and Hypertrophy of the heart (Transcription in the broken heart) [Genes]    Stathmin and breast cancer resistance to antimicrotubule agents [Genes]    Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation [Genes]    Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway [Genes]    Transcription factor CREB and its extracellular signals [Genes]    Signaling Pathway from G-Protein Families [Genes]    Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) [Genes]    AKAP95 role in mitosis and chromosome dynamics [Genes]    Attenuation of GPCR Signaling [Genes]    Regulation of BAD phosphorylation [Genes]    ChREBP regulation by carbohydrates and cAMP [Genes]    How Progesterone Initiates the Oocyte Maturation [Genes]    Actions of Nitric Oxide in the Heart [Genes]    Phospholipase C-epsilon pathway [Genes]    Protein Kinase A at the Centrosome [Genes]   
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Calcium signaling pathway    Chemokine signaling pathway    Oocyte meiosis    Apoptosis    Adrenergic signaling in cardiomyocytes    Vascular smooth muscle contraction    Wnt signaling pathway    Hedgehog signaling pathway    Gap junction    Circadian entrainment    Long-term potentiation    Retrograde endocannabinoid signaling    Glutamatergic synapse    Cholinergic synapse    Serotonergic synapse    GABAergic synapse    Dopaminergic synapse    Olfactory transduction    Taste transduction    Insulin signaling pathway    Insulin secretion    GnRH signaling pathway    Ovarian steroidogenesis    Progesterone-mediated oocyte maturation    Estrogen signaling pathway    Melanogenesis    Thyroid hormone synthesis    Thyroid hormone signaling pathway    Endocrine and other factor-regulated calcium reabsorption    Vasopressin-regulated water reabsorption    Salivary secretion    Gastric acid secretion    Bile secretion    Parkinson's disease    Prion diseases    Cocaine addiction    Amphetamine addiction    Morphine addiction    Vibrio cholerae infection    Amoebiasis    HTLV-I infection    Epstein-Barr virus infection    Viral carcinogenesis    Proteoglycans in cancer    Dilated cardiomyopathy   
NDEx NetworkPRKACG
Atlas of Cancer Signalling NetworkPRKACG
Wikipedia pathwaysPRKACG
Orthology - Evolution
OrthoDB5568
GeneTree (enSembl)ENSG00000165059
Phylogenetic Trees/Animal Genes : TreeFamPRKACG
HOVERGENP22612
HOGENOMP22612
Homologs : HomoloGenePRKACG
Homology/Alignments : Family Browser (UCSC)PRKACG
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRKACG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRKACG
dbVarPRKACG
ClinVarPRKACG
1000_GenomesPRKACG 
Exome Variant ServerPRKACG
ExAC (Exome Aggregation Consortium)PRKACG (select the gene name)
Genetic variants : HAPMAP5568
Genomic Variants (DGV)PRKACG [DGVbeta]
DECIPHER (Syndromes)9:71627449-71629039  ENSG00000165059
CONAN: Copy Number AnalysisPRKACG 
Mutations
ICGC Data PortalPRKACG 
TCGA Data PortalPRKACG 
Broad Tumor PortalPRKACG
OASIS PortalPRKACG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRKACG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRKACG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRKACG
DgiDB (Drug Gene Interaction Database)PRKACG
DoCM (Curated mutations)PRKACG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRKACG (select a term)
intoGenPRKACG
Cancer3DPRKACG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176893    616176   
Orphanet23368   
MedgenPRKACG
Genetic Testing Registry PRKACG
NextProtP22612 [Medical]
TSGene5568
GENETestsPRKACG
Huge Navigator PRKACG [HugePedia]
snp3D : Map Gene to Disease5568
BioCentury BCIQPRKACG
ClinGenPRKACG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5568
Chemical/Pharm GKB GenePA33750
Clinical trialPRKACG
Miscellaneous
canSAR (ICR)PRKACG (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRKACG
EVEXPRKACG
GoPubMedPRKACG
iHOPPRKACG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:15:38 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.