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PRKAG1 (protein kinase, AMP-activated, gamma 1 non-catalytic subunit)

Identity

Other namesAMPKG
HGNC (Hugo) PRKAG1
LocusID (NCBI) 5571
Location 12q13.12
Location_base_pair Starts at 49396055 and ends at 49412629 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PRKAG1   9385
Cards
Entrez_Gene (NCBI)PRKAG1  5571  protein kinase, AMP-activated, gamma 1 non-catalytic subunit
GeneCards (Weizmann)PRKAG1
Ensembl (Hinxton)ENSG00000181929 [Gene_View]  chr12:49396055-49412629 [Contig_View]  PRKAG1 [Vega]
ICGC DataPortalENSG00000181929
cBioPortalPRKAG1
AceView (NCBI)PRKAG1
Genatlas (Paris)PRKAG1
WikiGenes5571
SOURCE (Princeton)NM_001206709 NM_001206710 NM_002733 NM_212461
Genomic and cartography
GoldenPath (UCSC)PRKAG1  -  12q13.12   chr12:49396055-49412629 -  12q13.12   [Description]    (hg19-Feb_2009)
EnsemblPRKAG1 - 12q13.12 [CytoView]
Mapping of homologs : NCBIPRKAG1 [Mapview]
OMIM602742   
Gene and transcription
Genbank (Entrez)AK097606 AK293332 AK303276 AK307994 AK310250
RefSeq transcript (Entrez)NM_001206709 NM_001206710 NM_002733 NM_212461
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NT_029419 NW_001838057 NW_004929384
Consensus coding sequences : CCDS (NCBI)PRKAG1
Cluster EST : UnigeneHs.530862 [ NCBI ]
CGAP (NCI)Hs.530862
Alternative Splicing : Fast-db (Paris)GSHG0007435
Alternative Splicing GalleryENSG00000181929
Gene ExpressionPRKAG1 [ NCBI-GEO ]     PRKAG1 [ SEEK ]   PRKAG1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54619 (Uniprot)
NextProtP54619  [Medical]
With graphics : InterProP54619
Splice isoforms : SwissVarP54619 (Swissvar)
Domaine pattern : Prosite (Expaxy)CBS (PS51371)   
Domains : Interpro (EBI)CBS_dom [organisation]  
Related proteins : CluSTrP54619
Domain families : Pfam (Sanger)CBS (PF00571)   
Domain families : Pfam (NCBI)pfam00571   
Domain families : Smart (EMBL)CBS (SM00116)  
DMDM Disease mutations5571
Blocks (Seattle)P54619
PDB (SRS)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF   
PDB (PDBSum)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF   
PDB (IMB)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF   
PDB (RSDB)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF   
Human Protein AtlasENSG00000181929 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP54619
HPRD04118
IPIIPI00473047   IPI00883914   IPI01018162   IPI01022680   IPI01022963   IPI01021865   IPI01022314   IPI01021524   IPI01021692   IPI01021842   IPI01020775   IPI01020920   IPI01021060   IPI01021199   IPI01022558   IPI01022721   IPI01022829   
Protein Interaction databases
DIP (DOE-UCLA)P54619
IntAct (EBI)P54619
FunCoupENSG00000181929
BioGRIDPRKAG1
InParanoidP54619
Interologous Interaction database P54619
IntegromeDBPRKAG1
STRING (EMBL)PRKAG1
Ontologies - Pathways
Ontology : AmiGOprotein kinase activity  AMP-activated protein kinase activity  cAMP-dependent protein kinase activity  protein binding  ATP binding  nucleus  cytosol  regulation of glycolytic process  protein phosphorylation  fatty acid biosynthetic process  cell cycle arrest  signal transduction  spermatogenesis  insulin receptor signaling pathway  cAMP-dependent protein kinase regulator activity  positive regulation of gene expression  membrane  AMP binding  protein kinase binding  AMP-activated protein kinase complex  ADP binding  positive regulation of protein kinase activity  protein heterooligomerization  membrane organization  extracellular vesicular exosome  
Ontology : EGO-EBIprotein kinase activity  AMP-activated protein kinase activity  cAMP-dependent protein kinase activity  protein binding  ATP binding  nucleus  cytosol  regulation of glycolytic process  protein phosphorylation  fatty acid biosynthetic process  cell cycle arrest  signal transduction  spermatogenesis  insulin receptor signaling pathway  cAMP-dependent protein kinase regulator activity  positive regulation of gene expression  membrane  AMP binding  protein kinase binding  AMP-activated protein kinase complex  ADP binding  positive regulation of protein kinase activity  protein heterooligomerization  membrane organization  extracellular vesicular exosome  
Pathways : BIOCARTAReversal of Insulin Resistance by Leptin [Genes]    Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation [Genes]    ChREBP regulation by carbohydrates and cAMP [Genes]    AKAP95 role in mitosis and chromosome dynamics [Genes]    Protein Kinase A at the Centrosome [Genes]   
Pathways : KEGGFoxO signaling pathway    Circadian rhythm    Insulin signaling pathway    Adipocytokine signaling pathway    Non-alcoholic fatty liver disease (NAFLD)    Hypertrophic cardiomyopathy (HCM)   
Protein Interaction DatabasePRKAG1
Wikipedia pathwaysPRKAG1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PRKAG1
snp3D : Map Gene to Disease5571
SNP (GeneSNP Utah)PRKAG1
SNP : HGBasePRKAG1
Genetic variants : HAPMAPPRKAG1
Exome VariantPRKAG1
1000_GenomesPRKAG1 
ICGC programENSG00000181929 
Somatic Mutations in Cancer : COSMICPRKAG1 
CONAN: Copy Number AnalysisPRKAG1 
Mutations and Diseases : HGMDPRKAG1
Mutations and Diseases : intOGenPRKAG1
Genomic VariantsPRKAG1  PRKAG1 [DGVbeta]
dbVarPRKAG1
ClinVarPRKAG1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM602742   
MedgenPRKAG1
GENETestsPRKAG1
Disease Genetic AssociationPRKAG1
Huge Navigator PRKAG1 [HugePedia]  PRKAG1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGenePRKAG1
Homology/Alignments : Family Browser (UCSC)PRKAG1
Phylogenetic Trees/Animal Genes : TreeFamPRKAG1
Chemical/Protein Interactions : CTD5571
Chemical/Pharm GKB GenePA33751
Clinical trialPRKAG1
Cancer Resource (Charite)ENSG00000181929
Other databases
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
CoreMinePRKAG1
iHOPPRKAG1
OncoSearchPRKAG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 17:01:08 CEST 2014

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