Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PRKAG1 (protein kinase, AMP-activated, gamma 1 non-catalytic subunit)

Identity

Other namesAMPKG
HGNC (Hugo) PRKAG1
LocusID (NCBI) 5571
Atlas_Id 41849
Location 12q13.12
Location_base_pair Starts at 49396055 and ends at 49412629 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRKAG1   9385
Cards
Entrez_Gene (NCBI)PRKAG1  5571  protein kinase, AMP-activated, gamma 1 non-catalytic subunit
GeneCards (Weizmann)PRKAG1
Ensembl hg19 (Hinxton)ENSG00000181929 [Gene_View]  chr12:49396055-49412629 [Contig_View]  PRKAG1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000181929 [Gene_View]  chr12:49396055-49412629 [Contig_View]  PRKAG1 [Vega]
ICGC DataPortalENSG00000181929
TCGA cBioPortalPRKAG1
AceView (NCBI)PRKAG1
Genatlas (Paris)PRKAG1
WikiGenes5571
SOURCE (Princeton)PRKAG1
Genomic and cartography
GoldenPath hg19 (UCSC)PRKAG1  -     chr12:49396055-49412629 -  12q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PRKAG1  -     12q13.12   [Description]    (hg38-Dec_2013)
EnsemblPRKAG1 - 12q13.12 [CytoView hg19]  PRKAG1 - 12q13.12 [CytoView hg38]
Mapping of homologs : NCBIPRKAG1 [Mapview hg19]  PRKAG1 [Mapview hg38]
OMIM602742   
Gene and transcription
Genbank (Entrez)AK097606 AK293332 AK303276 AK307994 AK310250
RefSeq transcript (Entrez)NM_001206709 NM_001206710 NM_002733 NM_212461
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)PRKAG1
Cluster EST : UnigeneHs.530862 [ NCBI ]
CGAP (NCI)Hs.530862
Alternative Splicing : Fast-db (Paris)GSHG0007435
Alternative Splicing GalleryENSG00000181929
Gene ExpressionPRKAG1 [ NCBI-GEO ]     PRKAG1 [ SEEK ]   PRKAG1 [ MEM ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)5571
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54619 (Uniprot)
NextProtP54619  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP54619
Splice isoforms : SwissVarP54619 (Swissvar)
PhosPhoSitePlusP54619
Domaine pattern : Prosite (Expaxy)CBS (PS51371)   
Domains : Interpro (EBI)CBS_dom   
Domain families : Pfam (Sanger)CBS (PF00571)   
Domain families : Pfam (NCBI)pfam00571   
Domain families : Smart (EMBL)CBS (SM00116)  
DMDM Disease mutations5571
Blocks (Seattle)PRKAG1
PDB (SRS)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF    4RER    4REW   
PDB (PDBSum)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF    4RER    4REW   
PDB (IMB)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF    4RER    4REW   
PDB (RSDB)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF    4RER    4REW   
Structural Biology KnowledgeBase2UV4    2UV5    2UV6    2UV7    4CFE    4CFF    4RER    4REW   
SCOP (Structural Classification of Proteins)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF    4RER    4REW   
CATH (Classification of proteins structures)2UV4    2UV5    2UV6    2UV7    4CFE    4CFF    4RER    4REW   
Human Protein AtlasENSG00000181929
Peptide AtlasP54619
HPRD04118
IPIIPI00473047   IPI00883914   IPI01018162   IPI01022680   IPI01022963   IPI01021865   IPI01022314   IPI01021524   IPI01021692   IPI01021842   IPI01020775   IPI01020920   IPI01021060   IPI01021199   IPI01022558   IPI01022721   IPI01022829   
Protein Interaction databases
DIP (DOE-UCLA)P54619
IntAct (EBI)P54619
FunCoupENSG00000181929
BioGRIDPRKAG1
IntegromeDBPRKAG1
STRING (EMBL)PRKAG1
ZODIACPRKAG1
Ontologies - Pathways
QuickGOP54619
Ontology : AmiGOprotein kinase activity  AMP-activated protein kinase activity  cAMP-dependent protein kinase activity  protein binding  ATP binding  nucleus  cytosol  regulation of glycolytic process  transcription initiation from RNA polymerase II promoter  protein phosphorylation  fatty acid biosynthetic process  organelle organization  mitochondrion organization  cell cycle arrest  signal transduction  spermatogenesis  insulin receptor signaling pathway  cAMP-dependent protein kinase regulator activity  gene expression  positive regulation of gene expression  membrane  AMP binding  macroautophagy  protein kinase binding  nucleotide-activated protein kinase complex  ADP binding  positive regulation of protein kinase activity  membrane organization  extracellular exosome  
Ontology : EGO-EBIprotein kinase activity  AMP-activated protein kinase activity  cAMP-dependent protein kinase activity  protein binding  ATP binding  nucleus  cytosol  regulation of glycolytic process  transcription initiation from RNA polymerase II promoter  protein phosphorylation  fatty acid biosynthetic process  organelle organization  mitochondrion organization  cell cycle arrest  signal transduction  spermatogenesis  insulin receptor signaling pathway  cAMP-dependent protein kinase regulator activity  gene expression  positive regulation of gene expression  membrane  AMP binding  macroautophagy  protein kinase binding  nucleotide-activated protein kinase complex  ADP binding  positive regulation of protein kinase activity  membrane organization  extracellular exosome  
Pathways : BIOCARTAReversal of Insulin Resistance by Leptin [Genes]    Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation [Genes]    ChREBP regulation by carbohydrates and cAMP [Genes]    AKAP95 role in mitosis and chromosome dynamics [Genes]    Protein Kinase A at the Centrosome [Genes]   
Pathways : KEGGFoxO signaling pathway    Circadian rhythm    Insulin signaling pathway    Adipocytokine signaling pathway    Non-alcoholic fatty liver disease (NAFLD)    Hypertrophic cardiomyopathy (HCM)   
Protein Interaction DatabasePRKAG1
Atlas of Cancer Signalling NetworkPRKAG1
Wikipedia pathwaysPRKAG1
Orthology - Evolution
OrthoDB5571
GeneTree (enSembl)ENSG00000181929
Phylogenetic Trees/Animal Genes : TreeFamPRKAG1
Homologs : HomoloGenePRKAG1
Homology/Alignments : Family Browser (UCSC)PRKAG1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerPRKAG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRKAG1
dbVarPRKAG1
ClinVarPRKAG1
1000_GenomesPRKAG1 
Exome Variant ServerPRKAG1
Exome Aggregation Consortium (ExAC)ENSG00000181929
SNP (GeneSNP Utah)PRKAG1
SNP : HGBasePRKAG1
Genetic variants : HAPMAPPRKAG1
Genomic Variants (DGV)PRKAG1 [DGVbeta]
Mutations
ICGC Data PortalPRKAG1 
TCGA Data PortalPRKAG1 
Tumor PortalPRKAG1
TCGA Copy Number PortalPRKAG1
Somatic Mutations in Cancer : COSMICPRKAG1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRKAG1
DgiDB (Drug Gene Interaction Database)PRKAG1
DoCM (Curated mutations)PRKAG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRKAG1 (select a term)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:49396055-49412629
CONAN: Copy Number AnalysisPRKAG1 
Mutations and Diseases : HGMDPRKAG1
OMIM602742   
MedgenPRKAG1
NextProtP54619 [Medical]
TSGene5571
GENETestsPRKAG1
Huge Navigator PRKAG1 [HugePedia]  PRKAG1 [HugeCancerGEM]
snp3D : Map Gene to Disease5571
BioCentury BCIQPRKAG1
General knowledge
Chemical/Protein Interactions : CTD5571
Chemical/Pharm GKB GenePA33751
Clinical trialPRKAG1
Other databases
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRKAG1
GoPubMedPRKAG1
iHOPPRKAG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jan 16 19:18:41 CET 2016

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