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PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3)

Identity

Alias_namesprotein kinase
Other aliasAMPKG3
HGNC (Hugo) PRKAG3
LocusID (NCBI) 53632
Atlas_Id 46886
Location 2q35  [Link to chromosome band 2q35]
Location_base_pair Starts at 218822383 and ends at 218831789 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRKAG3   9387
Cards
Entrez_Gene (NCBI)PRKAG3  53632  protein kinase AMP-activated non-catalytic subunit gamma 3
AliasesAMPKG3
GeneCards (Weizmann)PRKAG3
Ensembl hg19 (Hinxton)ENSG00000115592 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115592 [Gene_View]  chr2:218822383-218831789 [Contig_View]  PRKAG3 [Vega]
ICGC DataPortalENSG00000115592
TCGA cBioPortalPRKAG3
AceView (NCBI)PRKAG3
Genatlas (Paris)PRKAG3
WikiGenes53632
SOURCE (Princeton)PRKAG3
Genetics Home Reference (NIH)PRKAG3
Genomic and cartography
GoldenPath hg38 (UCSC)PRKAG3  -     chr2:218822383-218831789 -  2q35   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRKAG3  -     2q35   [Description]    (hg19-Feb_2009)
EnsemblPRKAG3 - 2q35 [CytoView hg19]  PRKAG3 - 2q35 [CytoView hg38]
Mapping of homologs : NCBIPRKAG3 [Mapview hg19]  PRKAG3 [Mapview hg38]
OMIM604976   
Gene and transcription
Genbank (Entrez)AA256383 AF214519 AJ249977 AK300078 AK300687
RefSeq transcript (Entrez)NM_017431
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRKAG3
Cluster EST : UnigeneHs.591634 [ NCBI ]
CGAP (NCI)Hs.591634
Alternative Splicing GalleryENSG00000115592
Gene ExpressionPRKAG3 [ NCBI-GEO ]   PRKAG3 [ EBI - ARRAY_EXPRESS ]   PRKAG3 [ SEEK ]   PRKAG3 [ MEM ]
Gene Expression Viewer (FireBrowse)PRKAG3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53632
GTEX Portal (Tissue expression)PRKAG3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UGI9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UGI9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UGI9
Splice isoforms : SwissVarQ9UGI9
PhosPhoSitePlusQ9UGI9
Domaine pattern : Prosite (Expaxy)CBS (PS51371)   
Domains : Interpro (EBI)CBS_dom   
Domain families : Pfam (Sanger)CBS (PF00571)   
Domain families : Pfam (NCBI)pfam00571   
Domain families : Smart (EMBL)CBS (SM00116)  
Conserved Domain (NCBI)PRKAG3
DMDM Disease mutations53632
Blocks (Seattle)PRKAG3
SuperfamilyQ9UGI9
Human Protein AtlasENSG00000115592
Peptide AtlasQ9UGI9
HPRD16085
IPIIPI00220340   IPI00644202   IPI01014589   IPI00909148   IPI00927094   
Protein Interaction databases
DIP (DOE-UCLA)Q9UGI9
IntAct (EBI)Q9UGI9
FunCoupENSG00000115592
BioGRIDPRKAG3
STRING (EMBL)PRKAG3
ZODIACPRKAG3
Ontologies - Pathways
QuickGOQ9UGI9
Ontology : AmiGOAMP-activated protein kinase activity  ATP binding  extracellular space  nucleoplasm  cytosol  glycogen biosynthetic process  protein phosphorylation  fatty acid biosynthetic process  cell cycle arrest  glucose transport  macroautophagy  protein kinase binding  nucleotide-activated protein kinase complex  intracellular signal transduction  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIAMP-activated protein kinase activity  ATP binding  extracellular space  nucleoplasm  cytosol  glycogen biosynthetic process  protein phosphorylation  fatty acid biosynthetic process  cell cycle arrest  glucose transport  macroautophagy  protein kinase binding  nucleotide-activated protein kinase complex  intracellular signal transduction  regulation of signal transduction by p53 class mediator  
Pathways : BIOCARTAReversal of Insulin Resistance by Leptin [Genes]    ChREBP regulation by carbohydrates and cAMP [Genes]   
Pathways : KEGGFoxO signaling pathway    Circadian rhythm    Insulin signaling pathway    Adipocytokine signaling pathway    Non-alcoholic fatty liver disease (NAFLD)    Hypertrophic cardiomyopathy (HCM)   
NDEx NetworkPRKAG3
Atlas of Cancer Signalling NetworkPRKAG3
Wikipedia pathwaysPRKAG3
Orthology - Evolution
OrthoDB53632
GeneTree (enSembl)ENSG00000115592
Phylogenetic Trees/Animal Genes : TreeFamPRKAG3
HOVERGENQ9UGI9
HOGENOMQ9UGI9
Homologs : HomoloGenePRKAG3
Homology/Alignments : Family Browser (UCSC)PRKAG3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRKAG3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRKAG3
dbVarPRKAG3
ClinVarPRKAG3
1000_GenomesPRKAG3 
Exome Variant ServerPRKAG3
ExAC (Exome Aggregation Consortium)PRKAG3 (select the gene name)
Genetic variants : HAPMAP53632
Genomic Variants (DGV)PRKAG3 [DGVbeta]
DECIPHERPRKAG3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRKAG3 
Mutations
ICGC Data PortalPRKAG3 
TCGA Data PortalPRKAG3 
Broad Tumor PortalPRKAG3
OASIS PortalPRKAG3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRKAG3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRKAG3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRKAG3
DgiDB (Drug Gene Interaction Database)PRKAG3
DoCM (Curated mutations)PRKAG3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRKAG3 (select a term)
intoGenPRKAG3
Cancer3DPRKAG3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604976   
Orphanet
MedgenPRKAG3
Genetic Testing Registry PRKAG3
NextProtQ9UGI9 [Medical]
TSGene53632
GENETestsPRKAG3
Target ValidationPRKAG3
Huge Navigator PRKAG3 [HugePedia]
snp3D : Map Gene to Disease53632
BioCentury BCIQPRKAG3
ClinGenPRKAG3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD53632
Chemical/Pharm GKB GenePA33753
Clinical trialPRKAG3
Miscellaneous
canSAR (ICR)PRKAG3 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRKAG3
EVEXPRKAG3
GoPubMedPRKAG3
iHOPPRKAG3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:26:29 CEST 2017

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