PRKCQ (protein kinase C, theta)

Identity

Other names	MGC126514
	MGC141919
	PRKCT
	nPKC-theta
HGNC	PRKCQ
Location	10p15
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PRKCQ   9410
Entrez_Gene	PRKCQ  5588  protein kinase C, theta
	Cards
GeneCards	PRKCQ
Ensembl	PRKCQ [Search_View]   ENSG00000065675 [Gene_View]
Genatlas	PRKCQ
GeneLynx	PRKCQ
eGenome	PRKCQ
euGene	5588
	Genomic and cartography
GoldenPath	PRKCQ  -  10p15   chr10:6509111-6662244 -  10p15.1   [Description]    (hg18-March_2006)
Ensembl	PRKCQ - 10p15.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PRKCQ
	Gene and transcription
Genbank	AI570478 [ ENTREZ ]
Genbank	AK293935 [ ENTREZ ]
Genbank	AK308099 [ ENTREZ ]
Genbank	AK312411 [ ENTREZ ]
Genbank	AU099414 [ ENTREZ ]
RefSeq	NM_006257 [ SRS ]    NM_006257 [ ENTREZ ]
RefSeq	AC_000053 [ SRS ]    AC_000053 [ ENTREZ ]
RefSeq	AC_000142 [ SRS ]    AC_000142 [ ENTREZ ]
RefSeq	NC_000010 [ SRS ]    NC_000010 [ ENTREZ ]
RefSeq	NT_077569 [ SRS ]    NT_077569 [ ENTREZ ]
RefSeq	NW_001837931 [ SRS ]    NW_001837931 [ ENTREZ ]
RefSeq	NW_924584 [ SRS ]    NW_924584 [ ENTREZ ]
AceView	PRKCQ AceView - NCBI
Unigene	Hs.498570 [ SRS ]    Hs.498570 [ NCBI ]     HS498570 [ spliceNest ]
Fast-db	1732 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q04759 [ SRS]    Q04759 [ EXPASY ]     Q04759 [ INTERPRO ]     Q04759 [ UNIPROT ]
Prosite	PS51285 AGC_KINASE_CTER [ SRS ]    PS51285 AGC_KINASE_CTER [ Expasy ]
Prosite	PS50004 C2 [ SRS ]    PS50004 C2 [ Expasy ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Prosite	PS00479 ZF_DAG_PE_1 [ SRS ]    PS00479 ZF_DAG_PE_1 [ Expasy ]
Prosite	PS50081 ZF_DAG_PE_2 [ SRS ]    PS50081 ZF_DAG_PE_2 [ Expasy ]
Interpro	IPR000008 C2_Ca-dep [ SRS ]    IPR000008 C2_Ca-dep [ EBI ]
Interpro	IPR002219 DAG_PE_bd [ SRS ]    IPR002219 DAG_PE_bd [ EBI ]
Interpro	IPR015745 PKC [ SRS ]    IPR015745 PKC [ EBI ]
Interpro	IPR000961 Pkinase_C [ SRS ]    IPR000961 Pkinase_C [ EBI ]
Interpro	IPR014376 Prot_kin_PKC_delta [ SRS ]    IPR014376 Prot_kin_PKC_delta [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	Q04759
Pfam	PF00130 C1_1 [ SRS ]    PF00130 C1_1 [ Sanger ]    pfam00130 [ NCBI-CDD ]
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Pfam	PF00433 Pkinase_C [ SRS ]    PF00433 Pkinase_C [ Sanger ]    pfam00433 [ NCBI-CDD ]
Smart	SM00109 C1 [EMBL]
Smart	SM00133 S_TK_X [EMBL]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q04759 KPCT_HUMAN [ Domain structure ]   Q04759 KPCT_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q04759
PDB	1XJD [ SRS ]    1XJD [ PdbSum ],   1XJD [ IMB ]   1XJD [ RSDB ]
PDB	2ENJ [ SRS ]    2ENJ [ PdbSum ],   2ENJ [ IMB ]   2ENJ [ RSDB ]
PDB	2ENN [ SRS ]    2ENN [ PdbSum ],   2ENN [ IMB ]   2ENN [ RSDB ]
PDB	2ENZ [ SRS ]    2ENZ [ PdbSum ],   2ENZ [ IMB ]   2ENZ [ RSDB ]
PDB	2JED [ SRS ]    2JED [ PdbSum ],   2JED [ IMB ]   2JED [ RSDB ]
HPRD	02710
	Protein Interaction databases
DIP	Q04759
IntAct	Q04759
	Polymorphism : SNP, mutations, diseases
OMIM	600448    [ map ]
GENECLINICS	600448
SNP	PRKCQ [dbSNP-NCBI]
SNP	NM_006257 [SNP-NCI]
SNP	PRKCQ [GeneSNPs - Utah]  PRKCQ] [HGBASE - SRS]
HAPMAP	PRKCQ [HAPMAP]
COSMIC	PRKCQ [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PRKCQ
	General knowledge
Family Browser	PRKCQ [UCSC Family Browser]
SOURCE	NM_006257
SMD	Hs.498570
SAGE	Hs.498570
Enzyme	2.7.11.13 [ Enzyme-Expasy ]   2.7.11.13 [ Enzyme-SRS ]   2.7.11.13 [ IntEnz-EBI ]   2.7.11.13 [ BRENDA ]   2.7.11.13 [ KEGG ]   2.7.11.13 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	regulation of cell growth [Amigo]  regulation of cell growth
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein kinase C activity [Amigo]  protein kinase C activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	ATP binding [Amigo]  ATP binding
GO	intracellular [Amigo]  intracellular
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	zinc ion binding [Amigo]  zinc ion binding
GO	transferase activity [Amigo]  transferase activity
GO	diacylglycerol binding [Amigo]  diacylglycerol binding
GO	positive regulation of NF-kappaB transcription factor activity [Amigo]  positive regulation of NF-kappaB transcription factor activity
BIOCARTA	Keratinocyte Differentiation    [Genes]
KEGG	Tight junction
KEGG	T cell receptor signaling pathway
KEGG	Adipocytokine signaling pathway
PubGene	PRKCQ
TreeFam	PRKCQ
CTD	5588 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PRKCQ Related clones (RZPD - Berlin)
	PubMed
PubMed	102 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:26:44 2008