PRKD3 (protein kinase D3)

Identity

Other names	EPK2
	PKC-NU
	PKD3
	PRKCN
	nPKC-NU
HGNC	PRKD3
Location	2p21
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PRKD3   9408
Entrez_Gene	PRKD3  23683  protein kinase D3
	Cards
GeneCards	PRKD3
Ensembl	PRKD3 [Search_View]   ENSG00000115825 [Gene_View]
Genatlas	PRKD3
GeneLynx	PRKD3
eGenome	PRKD3
euGene	23683
	Genomic and cartography
GoldenPath	PRKD3  -  2p21   chr2:37331150-37397726 -  2p22.2   [Description]    (hg18-March_2006)
Ensembl	PRKD3 - 2p22.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PRKD3
	Gene and transcription
Genbank	AA631772 [ ENTREZ ]
Genbank	AB015982 [ ENTREZ ]
Genbank	AK027585 [ ENTREZ ]
Genbank	AK122883 [ ENTREZ ]
Genbank	AW515068 [ ENTREZ ]
RefSeq	NM_005813 [ SRS ]    NM_005813 [ ENTREZ ]
RefSeq	AC_000045 [ SRS ]    AC_000045 [ ENTREZ ]
RefSeq	AC_000134 [ SRS ]    AC_000134 [ ENTREZ ]
RefSeq	NC_000002 [ SRS ]    NC_000002 [ ENTREZ ]
RefSeq	NT_022184 [ SRS ]    NT_022184 [ ENTREZ ]
RefSeq	NW_001838769 [ SRS ]    NW_001838769 [ ENTREZ ]
RefSeq	NW_927719 [ SRS ]    NW_927719 [ ENTREZ ]
AceView	PRKD3 AceView - NCBI
Unigene	Hs.696257 [ SRS ]    Hs.696257 [ NCBI ]     HS696257 [ spliceNest ]
Fast-db	4119 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O94806 [ SRS]    O94806 [ EXPASY ]     O94806 [ INTERPRO ]     O94806 [ UNIPROT ]
Prosite	PS50003 PH_DOMAIN [ SRS ]    PS50003 PH_DOMAIN [ Expasy ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Prosite	PS00479 ZF_DAG_PE_1 [ SRS ]    PS00479 ZF_DAG_PE_1 [ Expasy ]
Prosite	PS50081 ZF_DAG_PE_2 [ SRS ]    PS50081 ZF_DAG_PE_2 [ Expasy ]
Interpro	IPR002219 DAG_PE_bd [ SRS ]    IPR002219 DAG_PE_bd [ EBI ]
Interpro	IPR001849 PH [ SRS ]    IPR001849 PH [ EBI ]
Interpro	IPR011993 PH_type [ SRS ]    IPR011993 PH_type [ EBI ]
Interpro	IPR015727 PKC_mu_like [ SRS ]    IPR015727 PKC_mu_like [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	O94806
Pfam	PF00130 C1_1 [ SRS ]    PF00130 C1_1 [ Sanger ]    pfam00130 [ NCBI-CDD ]
Pfam	PF00169 PH [ SRS ]    PF00169 PH [ Sanger ]    pfam00169 [ NCBI-CDD ]
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00109 C1 [EMBL]
Smart	SM00233 PH [EMBL]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	O94806 KPCD3_HUMAN [ Domain structure ]   O94806 KPCD3_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	O94806
PDB	2D9Z [ SRS ]    2D9Z [ PdbSum ],   2D9Z [ IMB ]   2D9Z [ RSDB ]
HPRD	06151
	Protein Interaction databases
DIP	O94806
IntAct	O94806
	Polymorphism : SNP, mutations, diseases
OMIM	607077    [ map ]
GENECLINICS	607077
SNP	PRKD3 [dbSNP-NCBI]
SNP	NM_005813 [SNP-NCI]
SNP	PRKD3 [GeneSNPs - Utah]  PRKD3] [HGBASE - SRS]
HAPMAP	PRKD3 [HAPMAP]
COSMIC	PRKD3 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PRKD3
	General knowledge
Family Browser	PRKD3 [UCSC Family Browser]
SOURCE	NM_005813
SMD	Hs.696257
SAGE	Hs.696257
Enzyme	2.7.11.13 [ Enzyme-Expasy ]   2.7.11.13 [ Enzyme-SRS ]   2.7.11.13 [ IntEnz-EBI ]   2.7.11.13 [ BRENDA ]   2.7.11.13 [ KEGG ]   2.7.11.13 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein kinase C activity [Amigo]  protein kinase C activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	activation of protein kinase C activity [Amigo]  activation of protein kinase C activity
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	zinc ion binding [Amigo]  zinc ion binding
GO	transferase activity [Amigo]  transferase activity
GO	diacylglycerol binding [Amigo]  diacylglycerol binding
GO	metal ion binding [Amigo]  metal ion binding
PubGene	PRKD3
TreeFam	PRKD3
CTD	23683 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PRKD3 Related clones (RZPD - Berlin)
	PubMed
PubMed	30 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:26:45 2008