Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PRKRIP1 (PRKR interacting protein 1 (IL11 inducible))

Identity

Alias_symbol (synonym)C114
FLJ13902
KRBOX3
Other alias
HGNC (Hugo) PRKRIP1
LocusID (NCBI) 79706
Atlas_Id 54553
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 102036804 and ends at 102067129 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CAMKK2 (12q24.31) / PRKRIP1 (7q22.1)PMS2P3 (7q11.23) / PRKRIP1 (7q22.1)PRKRIP1 (7q22.1) / ANKRD13A (12q24.11)
PRKRIP1 (7q22.1) / CRACR2B (11p15.5)PRKRIP1 (7q22.1) / WDTC1 (1p36.11)WDTC1 (1p36.11) / PRKRIP1 (7q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRKRIP1   21894
Cards
Entrez_Gene (NCBI)PRKRIP1  79706  PRKR interacting protein 1 (IL11 inducible)
AliasesC114; KRBOX3
GeneCards (Weizmann)PRKRIP1
Ensembl hg19 (Hinxton)ENSG00000128563 [Gene_View]  chr7:102036804-102067129 [Contig_View]  PRKRIP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000128563 [Gene_View]  chr7:102036804-102067129 [Contig_View]  PRKRIP1 [Vega]
ICGC DataPortalENSG00000128563
TCGA cBioPortalPRKRIP1
AceView (NCBI)PRKRIP1
Genatlas (Paris)PRKRIP1
WikiGenes79706
SOURCE (Princeton)PRKRIP1
Genetics Home Reference (NIH)PRKRIP1
Genomic and cartography
GoldenPath hg19 (UCSC)PRKRIP1  -     chr7:102036804-102067129 +  7q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PRKRIP1  -     7q22.1   [Description]    (hg38-Dec_2013)
EnsemblPRKRIP1 - 7q22.1 [CytoView hg19]  PRKRIP1 - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBIPRKRIP1 [Mapview hg19]  PRKRIP1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK023964 AK097289 AK124753 AK294664 AL833837
RefSeq transcript (Entrez)NM_024653
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007933 NW_004929332
Consensus coding sequences : CCDS (NCBI)PRKRIP1
Cluster EST : UnigeneHs.722104 [ NCBI ]
CGAP (NCI)Hs.722104
Alternative Splicing GalleryENSG00000128563
Gene ExpressionPRKRIP1 [ NCBI-GEO ]   PRKRIP1 [ EBI - ARRAY_EXPRESS ]   PRKRIP1 [ SEEK ]   PRKRIP1 [ MEM ]
Gene Expression Viewer (FireBrowse)PRKRIP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79706
GTEX Portal (Tissue expression)PRKRIP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H875   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H875  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H875
Splice isoforms : SwissVarQ9H875
PhosPhoSitePlusQ9H875
Domains : Interpro (EBI)DUF1168   
Domain families : Pfam (Sanger)DUF1168 (PF06658)   
Domain families : Pfam (NCBI)pfam06658   
Conserved Domain (NCBI)PRKRIP1
DMDM Disease mutations79706
Blocks (Seattle)PRKRIP1
SuperfamilyQ9H875
Human Protein AtlasENSG00000128563
Peptide AtlasQ9H875
HPRD11460
IPIIPI00550781   IPI00910172   IPI00947061   
Protein Interaction databases
DIP (DOE-UCLA)Q9H875
IntAct (EBI)Q9H875
FunCoupENSG00000128563
BioGRIDPRKRIP1
STRING (EMBL)PRKRIP1
ZODIACPRKRIP1
Ontologies - Pathways
QuickGOQ9H875
Ontology : AmiGOrenal system process  double-stranded RNA binding  double-stranded RNA binding  protein kinase inhibitor activity  protein kinase inhibitor activity  protein binding  nucleolus  nucleolus  negative regulation of protein kinase activity  negative regulation of protein kinase activity  protein kinase binding  protein kinase binding  negative regulation of phosphorylation  extracellular exosome  negative regulation of cyclin-dependent protein kinase activity  
Ontology : EGO-EBIrenal system process  double-stranded RNA binding  double-stranded RNA binding  protein kinase inhibitor activity  protein kinase inhibitor activity  protein binding  nucleolus  nucleolus  negative regulation of protein kinase activity  negative regulation of protein kinase activity  protein kinase binding  protein kinase binding  negative regulation of phosphorylation  extracellular exosome  negative regulation of cyclin-dependent protein kinase activity  
NDEx NetworkPRKRIP1
Atlas of Cancer Signalling NetworkPRKRIP1
Wikipedia pathwaysPRKRIP1
Orthology - Evolution
OrthoDB79706
GeneTree (enSembl)ENSG00000128563
Phylogenetic Trees/Animal Genes : TreeFamPRKRIP1
HOVERGENQ9H875
HOGENOMQ9H875
Homologs : HomoloGenePRKRIP1
Homology/Alignments : Family Browser (UCSC)PRKRIP1
Gene fusions - Rearrangements
Fusion : MitelmanCAMKK2/PRKRIP1 [12q24.31/7q22.1]  [t(7;12)(q22;q24)]  
Fusion : MitelmanPRKRIP1/CRACR2B [7q22.1/11p15.5]  [t(7;11)(q22;p15)]  
Fusion : MitelmanPRKRIP1/WDTC1 [7q22.1/1p36.11]  [t(1;7)(p36;q22)]  
Fusion : MitelmanWDTC1/PRKRIP1 [1p36.11/7q22.1]  [t(1;7)(p36;q22)]  
Fusion Cancer (Beijing)PMS2P3 [7q11.23]  -  PRKRIP1 [7q22.1]  [FUSC000604]  [FUSC000604]  [FUSC000604]  [FUSC000604]  [FUSC000604]  [FUSC000604]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRKRIP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRKRIP1
dbVarPRKRIP1
ClinVarPRKRIP1
1000_GenomesPRKRIP1 
Exome Variant ServerPRKRIP1
ExAC (Exome Aggregation Consortium)PRKRIP1 (select the gene name)
Genetic variants : HAPMAP79706
Genomic Variants (DGV)PRKRIP1 [DGVbeta]
DECIPHER (Syndromes)7:102036804-102067129  ENSG00000128563
CONAN: Copy Number AnalysisPRKRIP1 
Mutations
ICGC Data PortalPRKRIP1 
TCGA Data PortalPRKRIP1 
Broad Tumor PortalPRKRIP1
OASIS PortalPRKRIP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRKRIP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRKRIP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRKRIP1
DgiDB (Drug Gene Interaction Database)PRKRIP1
DoCM (Curated mutations)PRKRIP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRKRIP1 (select a term)
intoGenPRKRIP1
Cancer3DPRKRIP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPRKRIP1
Genetic Testing Registry PRKRIP1
NextProtQ9H875 [Medical]
TSGene79706
GENETestsPRKRIP1
Huge Navigator PRKRIP1 [HugePedia]
snp3D : Map Gene to Disease79706
BioCentury BCIQPRKRIP1
ClinGenPRKRIP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79706
Chemical/Pharm GKB GenePA134952162
Clinical trialPRKRIP1
Miscellaneous
canSAR (ICR)PRKRIP1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRKRIP1
EVEXPRKRIP1
GoPubMedPRKRIP1
iHOPPRKRIP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:22:59 CET 2017

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