PRKX (protein kinase X-linked)

2006-10-01  

Identity

HGNC
PRKX
LOCATION
Xp22.33
LOCUSID
5613
ALIAS
PKX1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5613
MIM: 300083
HGNC: 9441
Ensembl: ENSG00000183943

Variants:

dbSNP: 5613
ClinVar: 5613
TCGA: ENSG00000183943
COSMIC: PRKX

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183943ENST00000262848P51817
ENSG00000183943ENST00000262848A0A024RBU5

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
220206232012PRKX, TTBK2 and RSK4 expression causes Sunitinib resistance in kidney carcinoma- and melanoma-cell lines.21
120821742002PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis.11
216842722011PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation.6
262529462016PRKX, a Novel cAMP-Dependent Protein Kinase Member, Plays an Important Role in Development.5
179801652008Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency.3
276302942016Altered Expression of PRKX, WNT3 and WNT16 in Human Nodular Basal Cell Carcinoma.1
219713122011MBD 4--a potential substrate for protein kinase X.0

Citation

Dessen P

PRKX (protein kinase X-linked)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43429/prkx