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PRL (prolactin)

Identity

Other names-
HGNC (Hugo) PRL
LocusID (NCBI) 5617
Location 6p22.3
Location_base_pair Starts at 22287473 and ends at 22297730 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PRL   9445
Entrez_Gene (NCBI)PRL  5617  prolactin
Cards
GeneCards (Weizmann)PRL
Ensembl (Hinxton)ENSG00000172179 [Gene_View]  chr6:22287473-22297730 [Contig_View]  PRL [Vega]
AceView (NCBI)PRL
Genatlas (Paris)PRL
SOURCE (Stanford)NM_000948 NM_001163558
Genomic and cartography
GoldenPath (UCSC)PRL  -  6p22.3   chr6:22287473-22297730 -  6p22.3   [Description]    (hg19-Feb_2009)
EnsemblPRL - 6p22.3 [CytoView]
Mapping of homologs : NCBIPRL [Mapview]
OMIM176760   
Gene and transcription
Genbank (Entrez)BC015850 BC088370 CD106243 D00411 DQ839492
RefSeq transcript (SRS)NM_000948 NM_001163558
RefSeq transcript (Entrez)NM_000948 NM_001163558
RefSeq genomic (SRS)AC_000138 NC_000006 NC_018917 NG_029819 NT_007592 NW_001838973 NW_004078026
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NG_029819 NT_007592 NW_001838973 NW_004078026
Consensus coding sequences : CCDS (NCBI)PRL
Cluster EST : UnigeneHs.735971 [ SRS ] Hs.735971 [ NCBI ]
CGAP (NCI)Hs.735971
Alternative Splicing : Fast-db (Paris)GSHG0026347
Alternative Splicing GalleryENSG00000172179
Gene ExpressionPRL [ NCBI-GEO ]   PRL [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01236 (SRS) P01236 (Uniprot)
NextProtP01236
With graphics : InterProP01236
Splice isoforms : SwissVarP01236(Swissvar)
Domaine pattern : Prosite (SRS)SOMATOTROPIN_1 (PS00266)    SOMATOTROPIN_2 (PS00338)   
Domaine pattern : Prosite (Expaxy)SOMATOTROPIN_1 (PS00266)    SOMATOTROPIN_2 (PS00338)   
Domains : Interpro (SRS)4_helix_cytokine-like_core    4_helix_cytokine_core    Somatotropin    Somatotropin_CS   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Somatotropin    Somatotropin_CS   
Related proteins : CluSTrP01236
Domain families : Pfam (SRS)Hormone_1 (PF00103)   
Domain families : Pfam (Sanger)Hormone_1 (PF00103)   
Domain families : Pfam (NCBI)pfam00103   
DMDM5617
Blocks (Seattle)P01236
PDB (SRS)1RW5    2Q98    3D48    3EW3    3MZG    3N06    3N0P    3NCB    3NCC    3NCE    3NCF    3NPZ   
PDB (PDBSum)1RW5    2Q98    3D48    3EW3    3MZG    3N06    3N0P    3NCB    3NCC    3NCE    3NCF    3NPZ   
PDB (IMB)1RW5    2Q98    3D48    3EW3    3MZG    3N06    3N0P    3NCB    3NCC    3NCE    3NCF    3NPZ   
PDB (RSDB)1RW5    2Q98    3D48    3EW3    3MZG    3N06    3N0P    3NCB    3NCC    3NCE    3NCF    3NPZ   
Human Protein AtlasENSG00000172179
HPRD07180
IPIIPI00855965   IPI00000871   
Protein Interaction databases
DIP (DOE-UCLA)P01236
IntAct (EBI)P01236
FunCoupENSG00000172179
REACTOMEPRL
Protein Interaction Database5617
BioGRIDPRL
InParanoidP01236
Interologous Interaction database P01236
IntegromeDBPRL
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PRL
SNP (GeneSNP Utah)PRL
SNP : HGBasePRL
Genetic variants : HAPMAPPRL
Somatic Mutations in Cancer : COSMICPRL 
CONAN: Copy Number AnalysisPRL 
Mutations and Diseases : HGMDPRL
OMIM176760   
GENETests176760   
Disease Genetic AssociationPRL
Huge Navigator PRL [HugePedia]  PRL [HugeCancerGEM]
Genomic VariantsPRL  PRL [DGVbeta]
snp3D : Map Gene to Disease5617
General knowledge
Homologs : HomoloGenePRL
Homology/Alignments : Family Browser (UCSC)PRL
Phylogenetic Trees/Animal Genes : TreeFamPRL
Chemical/Protein Interactions : CTD5617
Chemical/Pharm GKB GenePA33790
Clinical trialPRL
Cancer Resource (Charite)ENSG00000172179
Ontology : AmiGOprolactin receptor binding  hormone activity  extracellular region  cell surface receptor signaling pathway  female pregnancy  lactation  cell proliferation  regulation of multicellular organism growth  positive regulation of JAK-STAT cascade  JAK-STAT cascade involved in growth hormone signaling pathway  
Ontology : EGO-EBIprolactin receptor binding  hormone activity  extracellular region  cell surface receptor signaling pathway  female pregnancy  lactation  cell proliferation  regulation of multicellular organism growth  positive regulation of JAK-STAT cascade  JAK-STAT cascade involved in growth hormone signaling pathway  
Pathways : KEGGJak-STAT signaling pathwayNeuroactive ligand-receptor interactionCytokine-cytokine receptor interaction
Other databases
Probes
Litterature
PubMed194 Pubmed reference(s) in Entrez
PubGenePRL
iHOPPRL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:35:34 CEST 2013
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