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PRMT6 (protein arginine methyltransferase 6)

Identity

Alias_namesHRMT1L6
HMT1 hnRNP methyltransferase-like 6 (S. cerevisiae)
Alias_symbol (synonym)FLJ10559
Other alias
HGNC (Hugo) PRMT6
LocusID (NCBI) 55170
Atlas_Id 50961
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 107056645 and ends at 107059296 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRMT6   18241
Cards
Entrez_Gene (NCBI)PRMT6  55170  protein arginine methyltransferase 6
AliasesHRMT1L6
GeneCards (Weizmann)PRMT6
Ensembl hg19 (Hinxton)ENSG00000198890 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198890 [Gene_View]  chr1:107056645-107059296 [Contig_View]  PRMT6 [Vega]
ICGC DataPortalENSG00000198890
TCGA cBioPortalPRMT6
AceView (NCBI)PRMT6
Genatlas (Paris)PRMT6
WikiGenes55170
SOURCE (Princeton)PRMT6
Genetics Home Reference (NIH)PRMT6
Genomic and cartography
GoldenPath hg38 (UCSC)PRMT6  -     chr1:107056645-107059296 +  1p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRMT6  -     1p13.3   [Description]    (hg19-Feb_2009)
EnsemblPRMT6 - 1p13.3 [CytoView hg19]  PRMT6 - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBIPRMT6 [Mapview hg19]  PRMT6 [Mapview hg38]
OMIM608274   
Gene and transcription
Genbank (Entrez)AI754232 AK001421 AK226009 AK295541 AK297898
RefSeq transcript (Entrez)NM_018137
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRMT6
Cluster EST : UnigeneHs.26006 [ NCBI ]
CGAP (NCI)Hs.26006
Alternative Splicing GalleryENSG00000198890
Gene ExpressionPRMT6 [ NCBI-GEO ]   PRMT6 [ EBI - ARRAY_EXPRESS ]   PRMT6 [ SEEK ]   PRMT6 [ MEM ]
Gene Expression Viewer (FireBrowse)PRMT6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55170
GTEX Portal (Tissue expression)PRMT6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96LA8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96LA8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96LA8
Splice isoforms : SwissVarQ96LA8
PhosPhoSitePlusQ96LA8
Domaine pattern : Prosite (Expaxy)SAM_MT_PRMT (PS51678)   
Domains : Interpro (EBI)Arg_MeTrfase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PRMT6
DMDM Disease mutations55170
Blocks (Seattle)PRMT6
PDB (SRS)4HC4    4QPP    4QQK    4Y2H    4Y30    5E8R    5EGS    5HZM   
PDB (PDBSum)4HC4    4QPP    4QQK    4Y2H    4Y30    5E8R    5EGS    5HZM   
PDB (IMB)4HC4    4QPP    4QQK    4Y2H    4Y30    5E8R    5EGS    5HZM   
PDB (RSDB)4HC4    4QPP    4QQK    4Y2H    4Y30    5E8R    5EGS    5HZM   
Structural Biology KnowledgeBase4HC4    4QPP    4QQK    4Y2H    4Y30    5E8R    5EGS    5HZM   
SCOP (Structural Classification of Proteins)4HC4    4QPP    4QQK    4Y2H    4Y30    5E8R    5EGS    5HZM   
CATH (Classification of proteins structures)4HC4    4QPP    4QQK    4Y2H    4Y30    5E8R    5EGS    5HZM   
SuperfamilyQ96LA8
Human Protein AtlasENSG00000198890
Peptide AtlasQ96LA8
HPRD10505
IPIIPI00102128   IPI00909110   IPI00908412   
Protein Interaction databases
DIP (DOE-UCLA)Q96LA8
IntAct (EBI)Q96LA8
FunCoupENSG00000198890
BioGRIDPRMT6
STRING (EMBL)PRMT6
ZODIACPRMT6
Ontologies - Pathways
QuickGOQ96LA8
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  chromatin binding  protein binding  nucleus  nucleoplasm  nucleolus  base-excision repair  transcription, DNA-templated  histone-arginine N-methyltransferase activity  viral process  cell growth  protein-arginine N-methyltransferase activity  histone methylation  peptidyl-arginine methylation, to asymmetrical-dimethyl arginine  histone H3-R2 methylation  protein-arginine omega-N monomethyltransferase activity  protein-arginine omega-N asymmetric methyltransferase activity  histone methyltransferase activity  histone binding  histone H4-R3 methylation  histone methyltransferase activity (H4-R3 specific)  negative regulation of transcription, DNA-templated  histone methyltransferase activity (H3-R2 specific)  histone methyltransferase activity (H2A-R3 specific)  cellular senescence  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  chromatin binding  protein binding  nucleus  nucleoplasm  nucleolus  base-excision repair  transcription, DNA-templated  histone-arginine N-methyltransferase activity  viral process  cell growth  protein-arginine N-methyltransferase activity  histone methylation  peptidyl-arginine methylation, to asymmetrical-dimethyl arginine  histone H3-R2 methylation  protein-arginine omega-N monomethyltransferase activity  protein-arginine omega-N asymmetric methyltransferase activity  histone methyltransferase activity  histone binding  histone H4-R3 methylation  histone methyltransferase activity (H4-R3 specific)  negative regulation of transcription, DNA-templated  histone methyltransferase activity (H3-R2 specific)  histone methyltransferase activity (H2A-R3 specific)  cellular senescence  
NDEx NetworkPRMT6
Atlas of Cancer Signalling NetworkPRMT6
Wikipedia pathwaysPRMT6
Orthology - Evolution
OrthoDB55170
GeneTree (enSembl)ENSG00000198890
Phylogenetic Trees/Animal Genes : TreeFamPRMT6
HOVERGENQ96LA8
HOGENOMQ96LA8
Homologs : HomoloGenePRMT6
Homology/Alignments : Family Browser (UCSC)PRMT6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRMT6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRMT6
dbVarPRMT6
ClinVarPRMT6
1000_GenomesPRMT6 
Exome Variant ServerPRMT6
ExAC (Exome Aggregation Consortium)PRMT6 (select the gene name)
Genetic variants : HAPMAP55170
Genomic Variants (DGV)PRMT6 [DGVbeta]
DECIPHERPRMT6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRMT6 
Mutations
ICGC Data PortalPRMT6 
TCGA Data PortalPRMT6 
Broad Tumor PortalPRMT6
OASIS PortalPRMT6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRMT6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRMT6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRMT6
DgiDB (Drug Gene Interaction Database)PRMT6
DoCM (Curated mutations)PRMT6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRMT6 (select a term)
intoGenPRMT6
Cancer3DPRMT6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608274   
Orphanet
MedgenPRMT6
Genetic Testing Registry PRMT6
NextProtQ96LA8 [Medical]
TSGene55170
GENETestsPRMT6
Huge Navigator PRMT6 [HugePedia]
snp3D : Map Gene to Disease55170
BioCentury BCIQPRMT6
ClinGenPRMT6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55170
Chemical/Pharm GKB GenePA134992775
Clinical trialPRMT6
Miscellaneous
canSAR (ICR)PRMT6 (select the gene name)
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRMT6
EVEXPRMT6
GoPubMedPRMT6
iHOPPRMT6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:32:54 CEST 2017

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