PRMT9 (protein arginine methyltransferase 9)

2016-05-01  

Identity

HGNC
PRMT9
LOCATION
4q31.23
LOCUSID
90826
ALIAS
PRMT10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 90826
MIM: 616125
HGNC: 25099
Ensembl: ENSG00000164169

Variants:

dbSNP: 90826
ClinVar: 90826
TCGA: ENSG00000164169
COSMIC: PRMT9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164169ENST00000322396Q6P2P2
ENSG00000164169ENST00000514886D6REN0

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
257370132015PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145.53
259793442015Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2.24
279112652017MiRNA-543 promotes osteosarcoma cell proliferation and glycolysis by partially suppressing PRMT9 and stabilizing HIF-1α protein.18
296038302018PRMT9 promotes hepatocellular carcinoma invasion and metastasis via activating PI3K/Akt/GSK-3β/Snail signaling.12
257990062015Protein arginine methyltransferase 10 is required for androgen-dependent proliferation of LNCaP prostate cancer cells.3

Citation

Dessen P

PRMT9 (protein arginine methyltransferase 9)

Atlas Genet Cytogenet Oncol Haematol. 2016-05-01

Online version: http://atlasgeneticsoncology.org/gene/55771/prmt9