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PROK1 (prokineticin 1)

Identity

Alias_symbol (synonym)PK1
PRK1
EGVEGF
Other alias
HGNC (Hugo) PROK1
LocusID (NCBI) 84432
Atlas_Id 45762
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 110993788 and ends at 110999976 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PROK1   18454
Cards
Entrez_Gene (NCBI)PROK1  84432  prokineticin 1
AliasesEGVEGF; PK1; PRK1
GeneCards (Weizmann)PROK1
Ensembl hg19 (Hinxton)ENSG00000143125 [Gene_View]  chr1:110993788-110999976 [Contig_View]  PROK1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143125 [Gene_View]  chr1:110993788-110999976 [Contig_View]  PROK1 [Vega]
ICGC DataPortalENSG00000143125
TCGA cBioPortalPROK1
AceView (NCBI)PROK1
Genatlas (Paris)PROK1
WikiGenes84432
SOURCE (Princeton)PROK1
Genetics Home Reference (NIH)PROK1
Genomic and cartography
GoldenPath hg19 (UCSC)PROK1  -     chr1:110993788-110999976 +  1p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PROK1  -     1p13.3   [Description]    (hg38-Dec_2013)
EnsemblPROK1 - 1p13.3 [CytoView hg19]  PROK1 - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBIPROK1 [Mapview hg19]  PROK1 [Mapview hg38]
OMIM606233   
Gene and transcription
Genbank (Entrez)AF333024 AY029225 AY358683 BC025399 BM544315
RefSeq transcript (Entrez)NM_032414
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)PROK1
Cluster EST : UnigeneHs.514793 [ NCBI ]
CGAP (NCI)Hs.514793
Alternative Splicing GalleryENSG00000143125
Gene ExpressionPROK1 [ NCBI-GEO ]   PROK1 [ EBI - ARRAY_EXPRESS ]   PROK1 [ SEEK ]   PROK1 [ MEM ]
Gene Expression Viewer (FireBrowse)PROK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84432
GTEX Portal (Tissue expression)PROK1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP58294   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP58294  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP58294
Splice isoforms : SwissVarP58294
PhosPhoSitePlusP58294
Domains : Interpro (EBI)Prokineticin    Prokineticin_domain   
Domain families : Pfam (Sanger)Prokineticin (PF06607)   
Domain families : Pfam (NCBI)pfam06607   
Domain structure : Prodom (Prabi Lyon)Prokineticin (PD059788)   
Conserved Domain (NCBI)PROK1
DMDM Disease mutations84432
Blocks (Seattle)PROK1
SuperfamilyP58294
Human Protein AtlasENSG00000143125
Peptide AtlasP58294
HPRD06946
IPIIPI00033482   
Protein Interaction databases
DIP (DOE-UCLA)P58294
IntAct (EBI)P58294
FunCoupENSG00000143125
BioGRIDPROK1
STRING (EMBL)PROK1
ZODIACPROK1
Ontologies - Pathways
QuickGOP58294
Ontology : AmiGOactivation of MAPK activity  angiogenesis  G-protein coupled receptor binding  extracellular region  extracellular region  circadian rhythm  growth factor activity  positive regulation of cell proliferation  regulation of angiogenesis  positive regulation of cell division  
Ontology : EGO-EBIactivation of MAPK activity  angiogenesis  G-protein coupled receptor binding  extracellular region  extracellular region  circadian rhythm  growth factor activity  positive regulation of cell proliferation  regulation of angiogenesis  positive regulation of cell division  
NDEx NetworkPROK1
Atlas of Cancer Signalling NetworkPROK1
Wikipedia pathwaysPROK1
Orthology - Evolution
OrthoDB84432
GeneTree (enSembl)ENSG00000143125
Phylogenetic Trees/Animal Genes : TreeFamPROK1
HOVERGENP58294
HOGENOMP58294
Homologs : HomoloGenePROK1
Homology/Alignments : Family Browser (UCSC)PROK1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPROK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PROK1
dbVarPROK1
ClinVarPROK1
1000_GenomesPROK1 
Exome Variant ServerPROK1
ExAC (Exome Aggregation Consortium)PROK1 (select the gene name)
Genetic variants : HAPMAP84432
Genomic Variants (DGV)PROK1 [DGVbeta]
DECIPHER (Syndromes)1:110993788-110999976  ENSG00000143125
CONAN: Copy Number AnalysisPROK1 
Mutations
ICGC Data PortalPROK1 
TCGA Data PortalPROK1 
Broad Tumor PortalPROK1
OASIS PortalPROK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPROK1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPROK1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PROK1
DgiDB (Drug Gene Interaction Database)PROK1
DoCM (Curated mutations)PROK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PROK1 (select a term)
intoGenPROK1
Cancer3DPROK1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606233   
Orphanet
MedgenPROK1
Genetic Testing Registry PROK1
NextProtP58294 [Medical]
TSGene84432
GENETestsPROK1
Huge Navigator PROK1 [HugePedia]
snp3D : Map Gene to Disease84432
BioCentury BCIQPROK1
ClinGenPROK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84432
Chemical/Pharm GKB GenePA38539
Clinical trialPROK1
Miscellaneous
canSAR (ICR)PROK1 (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePROK1
EVEXPROK1
GoPubMedPROK1
iHOPPROK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:15:46 CEST 2017

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