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PROK2 (prokineticin 2)

Identity

Other namesBV8
HH4
KAL4
MIT1
PK2
HGNC (Hugo) PROK2
LocusID (NCBI) 60675
Location 3p13
Location_base_pair Starts at 71820806 and ends at 71834357 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PROK2   18455
Cards
Entrez_Gene (NCBI)PROK2  60675  prokineticin 2
GeneCards (Weizmann)PROK2
Ensembl (Hinxton)ENSG00000163421 [Gene_View]  chr3:71820806-71834357 [Contig_View]  PROK2 [Vega]
ICGC DataPortalENSG00000163421
AceView (NCBI)PROK2
Genatlas (Paris)PROK2
WikiGenes60675
SOURCE (Princeton)NM_001126128 NM_021935
Genomic and cartography
GoldenPath (UCSC)PROK2  -  3p13   chr3:71820806-71834357 -  3p13   [Description]    (hg19-Feb_2009)
EnsemblPROK2 - 3p13 [CytoView]
Mapping of homologs : NCBIPROK2 [Mapview]
OMIM607002   610628   
Gene and transcription
Genbank (Entrez)AF182069 AF333025 AY349131 BC069395 BC096695
RefSeq transcript (Entrez)NM_001126128 NM_021935
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_008275 NT_022517 NW_001838878 NW_004929310
Consensus coding sequences : CCDS (NCBI)PROK2
Cluster EST : UnigeneHs.528665 [ NCBI ]
CGAP (NCI)Hs.528665
Alternative Splicing : Fast-db (Paris)GSHG0021859
Alternative Splicing GalleryENSG00000163421
Gene ExpressionPROK2 [ NCBI-GEO ]     PROK2 [ SEEK ]   PROK2 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HC23 (Uniprot)
NextProtQ9HC23  [Medical]
With graphics : InterProQ9HC23
Splice isoforms : SwissVarQ9HC23 (Swissvar)
Domains : Interpro (EBI)Prokineticin    Prokineticin_domain   
Related proteins : CluSTrQ9HC23
Domain families : Pfam (Sanger)Prokineticin (PF06607)   
Domain families : Pfam (NCBI)pfam06607   
Domain structure : Prodom (Prabi Lyon)Prokineticin (PD059788)   
DMDM Disease mutations60675
Blocks (Seattle)Q9HC23
Human Protein AtlasENSG00000163421
Peptide AtlasQ9HC23
HPRD08446
IPIIPI00030045   IPI00220189   
Protein Interaction databases
DIP (DOE-UCLA)Q9HC23
IntAct (EBI)Q9HC23
FunCoupENSG00000163421
BioGRIDPROK2
InParanoidQ9HC23
Interologous Interaction database Q9HC23
IntegromeDBPROK2
STRING (EMBL)PROK2
Ontologies - Pathways
Ontology : AmiGOactivation of MAPK activity  angiogenesis  G-protein coupled receptor binding  extracellular region  chemotaxis  inflammatory response  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  spermatogenesis  circadian rhythm  cell proliferation  sensory perception of pain  negative regulation of apoptotic process  positive regulation of smooth muscle contraction  
Ontology : EGO-EBIactivation of MAPK activity  angiogenesis  G-protein coupled receptor binding  extracellular region  chemotaxis  inflammatory response  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  spermatogenesis  circadian rhythm  cell proliferation  sensory perception of pain  negative regulation of apoptotic process  positive regulation of smooth muscle contraction  
Protein Interaction DatabasePROK2
Wikipedia pathwaysPROK2
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PROK2
SNP (GeneSNP Utah)PROK2
SNP : HGBasePROK2
Genetic variants : HAPMAPPROK2
1000_GenomesPROK2 
ICGC programENSG00000163421 
CONAN: Copy Number AnalysisPROK2 
Somatic Mutations in Cancer : COSMICPROK2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDPROK2
OMIM607002    610628   
MedgenPROK2
GENETestsPROK2
Disease Genetic AssociationPROK2
Huge Navigator PROK2 [HugePedia]  PROK2 [HugeCancerGEM]
Genomic VariantsPROK2  PROK2 [DGVbeta]
Exome VariantPROK2
dbVarPROK2
ClinVarPROK2
snp3D : Map Gene to Disease60675
General knowledge
Homologs : HomoloGenePROK2
Homology/Alignments : Family Browser (UCSC)PROK2
Phylogenetic Trees/Animal Genes : TreeFamPROK2
Chemical/Protein Interactions : CTD60675
Chemical/Pharm GKB GenePA38540
Clinical trialPROK2
Cancer Resource (Charite)ENSG00000163421
Other databases
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
CoreMinePROK2
iHOPPROK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 13:10:34 CEST 2014

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