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PROKR1 (prokineticin receptor 1)

Identity

Alias_namesGPR73
G protein-coupled receptor 73
Alias_symbol (synonym)PKR1
ZAQ
GPR73a
Other aliasPK-R1
HGNC (Hugo) PROKR1
LocusID (NCBI) 10887
Atlas_Id 55884
Location 2p13.3  [Link to chromosome band 2p13]
Location_base_pair Starts at 68643588 and ends at 68655576 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RAC1 (7p22.1) / PROKR1 (2p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PROKR1   4524
Cards
Entrez_Gene (NCBI)PROKR1  10887  prokineticin receptor 1
AliasesGPR73; GPR73a; PK-R1; PKR1; 
ZAQ
GeneCards (Weizmann)PROKR1
Ensembl hg19 (Hinxton)ENSG00000169618 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169618 [Gene_View]  chr2:68643588-68655576 [Contig_View]  PROKR1 [Vega]
ICGC DataPortalENSG00000169618
TCGA cBioPortalPROKR1
AceView (NCBI)PROKR1
Genatlas (Paris)PROKR1
WikiGenes10887
SOURCE (Princeton)PROKR1
Genetics Home Reference (NIH)PROKR1
Genomic and cartography
GoldenPath hg38 (UCSC)PROKR1  -     chr2:68643588-68655576 +  2p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PROKR1  -     2p13.3   [Description]    (hg19-Feb_2009)
EnsemblPROKR1 - 2p13.3 [CytoView hg19]  PROKR1 - 2p13.3 [CytoView hg38]
Mapping of homologs : NCBIPROKR1 [Mapview hg19]  PROKR1 [Mapview hg38]
OMIM607122   
Gene and transcription
Genbank (Entrez)AB084080 AF506287 AY089976 BC100960 CD636583
RefSeq transcript (Entrez)NM_138964
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PROKR1
Cluster EST : UnigeneHs.719785 [ NCBI ]
CGAP (NCI)Hs.719785
Alternative Splicing GalleryENSG00000169618
Gene ExpressionPROKR1 [ NCBI-GEO ]   PROKR1 [ EBI - ARRAY_EXPRESS ]   PROKR1 [ SEEK ]   PROKR1 [ MEM ]
Gene Expression Viewer (FireBrowse)PROKR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10887
GTEX Portal (Tissue expression)PROKR1
Human Protein AtlasENSG00000169618-PROKR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCW9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCW9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCW9
Splice isoforms : SwissVarQ8TCW9
PhosPhoSitePlusQ8TCW9
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    NPY_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)PROKR1
DMDM Disease mutations10887
Blocks (Seattle)PROKR1
SuperfamilyQ8TCW9
Human Protein Atlas [tissue]ENSG00000169618-PROKR1 [tissue]
Peptide AtlasQ8TCW9
HPRD08452
IPIIPI00152470   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCW9
IntAct (EBI)Q8TCW9
FunCoupENSG00000169618
BioGRIDPROKR1
STRING (EMBL)PROKR1
ZODIACPROKR1
Ontologies - Pathways
QuickGOQ8TCW9
Ontology : AmiGOpancreatic polypeptide receptor activity  plasma membrane  neuropeptide signaling pathway  chemical synaptic transmission  circadian rhythm  feeding behavior  blood circulation  integral component of membrane  negative regulation of apoptotic process  
Ontology : EGO-EBIpancreatic polypeptide receptor activity  plasma membrane  neuropeptide signaling pathway  chemical synaptic transmission  circadian rhythm  feeding behavior  blood circulation  integral component of membrane  negative regulation of apoptotic process  
NDEx NetworkPROKR1
Atlas of Cancer Signalling NetworkPROKR1
Wikipedia pathwaysPROKR1
Orthology - Evolution
OrthoDB10887
GeneTree (enSembl)ENSG00000169618
Phylogenetic Trees/Animal Genes : TreeFamPROKR1
HOVERGENQ8TCW9
HOGENOMQ8TCW9
Homologs : HomoloGenePROKR1
Homology/Alignments : Family Browser (UCSC)PROKR1
Gene fusions - Rearrangements
Tumor Fusion PortalPROKR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPROKR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PROKR1
dbVarPROKR1
ClinVarPROKR1
1000_GenomesPROKR1 
Exome Variant ServerPROKR1
ExAC (Exome Aggregation Consortium)ENSG00000169618
GNOMAD BrowserENSG00000169618
Genetic variants : HAPMAP10887
Genomic Variants (DGV)PROKR1 [DGVbeta]
DECIPHERPROKR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPROKR1 
Mutations
ICGC Data PortalPROKR1 
TCGA Data PortalPROKR1 
Broad Tumor PortalPROKR1
OASIS PortalPROKR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPROKR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPROKR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PROKR1
DgiDB (Drug Gene Interaction Database)PROKR1
DoCM (Curated mutations)PROKR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PROKR1 (select a term)
intoGenPROKR1
Cancer3DPROKR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607122   
Orphanet
DisGeNETPROKR1
MedgenPROKR1
Genetic Testing Registry PROKR1
NextProtQ8TCW9 [Medical]
TSGene10887
GENETestsPROKR1
Target ValidationPROKR1
Huge Navigator PROKR1 [HugePedia]
snp3D : Map Gene to Disease10887
BioCentury BCIQPROKR1
ClinGenPROKR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10887
Chemical/Pharm GKB GenePA28916
Clinical trialPROKR1
Miscellaneous
canSAR (ICR)PROKR1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePROKR1
EVEXPROKR1
GoPubMedPROKR1
iHOPPROKR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:54:04 CET 2017

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