Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PROKR2 (prokineticin receptor 2)

Identity

Alias_namesGPR73L1
KAL3
G protein-coupled receptor 73-like 1
Kallmann syndrome 3 (autosomal dominant)
Alias_symbol (synonym)GPR73b
PKR2
GPRg2
dJ680N4.3
Other aliasHH3
HGNC (Hugo) PROKR2
LocusID (NCBI) 128674
Atlas_Id 56318
Location 20p12.3  [Link to chromosome band 20p12]
Location_base_pair Starts at 5301200 and ends at 5316732 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PROKR2   15836
Cards
Entrez_Gene (NCBI)PROKR2  128674  prokineticin receptor 2
AliasesGPR73L1; GPR73b; GPRg2; HH3; 
KAL3; PKR2; dJ680N4.3
GeneCards (Weizmann)PROKR2
Ensembl hg19 (Hinxton)ENSG00000101292 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101292 [Gene_View]  chr20:5301200-5316732 [Contig_View]  PROKR2 [Vega]
ICGC DataPortalENSG00000101292
TCGA cBioPortalPROKR2
AceView (NCBI)PROKR2
Genatlas (Paris)PROKR2
WikiGenes128674
SOURCE (Princeton)PROKR2
Genetics Home Reference (NIH)PROKR2
Genomic and cartography
GoldenPath hg38 (UCSC)PROKR2  -     chr20:5301200-5316732 -  20p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PROKR2  -     20p12.3   [Description]    (hg19-Feb_2009)
EnsemblPROKR2 - 20p12.3 [CytoView hg19]  PROKR2 - 20p12.3 [CytoView hg38]
Mapping of homologs : NCBIPROKR2 [Mapview hg19]  PROKR2 [Mapview hg38]
OMIM244200   607123   
Gene and transcription
Genbank (Entrez)AB084081 AF506288 AK289995 BC104959 BC104961
RefSeq transcript (Entrez)NM_144773
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PROKR2
Cluster EST : UnigeneHs.375029 [ NCBI ]
CGAP (NCI)Hs.375029
Alternative Splicing GalleryENSG00000101292
Gene ExpressionPROKR2 [ NCBI-GEO ]   PROKR2 [ EBI - ARRAY_EXPRESS ]   PROKR2 [ SEEK ]   PROKR2 [ MEM ]
Gene Expression Viewer (FireBrowse)PROKR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)128674
GTEX Portal (Tissue expression)PROKR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFJ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NFJ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NFJ6
Splice isoforms : SwissVarQ8NFJ6
PhosPhoSitePlusQ8NFJ6
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    NPY_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)PROKR2
DMDM Disease mutations128674
Blocks (Seattle)PROKR2
SuperfamilyQ8NFJ6
Human Protein AtlasENSG00000101292
Peptide AtlasQ8NFJ6
HPRD08453
IPIIPI00168843   
Protein Interaction databases
DIP (DOE-UCLA)Q8NFJ6
IntAct (EBI)Q8NFJ6
FunCoupENSG00000101292
BioGRIDPROKR2
STRING (EMBL)PROKR2
ZODIACPROKR2
Ontologies - Pathways
QuickGOQ8NFJ6
Ontology : AmiGOpancreatic polypeptide receptor activity  plasma membrane  plasma membrane  neuropeptide signaling pathway  chemical synaptic transmission  circadian rhythm  feeding behavior  blood circulation  integral component of membrane  
Ontology : EGO-EBIpancreatic polypeptide receptor activity  plasma membrane  plasma membrane  neuropeptide signaling pathway  chemical synaptic transmission  circadian rhythm  feeding behavior  blood circulation  integral component of membrane  
NDEx NetworkPROKR2
Atlas of Cancer Signalling NetworkPROKR2
Wikipedia pathwaysPROKR2
Orthology - Evolution
OrthoDB128674
GeneTree (enSembl)ENSG00000101292
Phylogenetic Trees/Animal Genes : TreeFamPROKR2
HOVERGENQ8NFJ6
HOGENOMQ8NFJ6
Homologs : HomoloGenePROKR2
Homology/Alignments : Family Browser (UCSC)PROKR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPROKR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PROKR2
dbVarPROKR2
ClinVarPROKR2
1000_GenomesPROKR2 
Exome Variant ServerPROKR2
ExAC (Exome Aggregation Consortium)PROKR2 (select the gene name)
Genetic variants : HAPMAP128674
Genomic Variants (DGV)PROKR2 [DGVbeta]
DECIPHERPROKR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPROKR2 
Mutations
ICGC Data PortalPROKR2 
TCGA Data PortalPROKR2 
Broad Tumor PortalPROKR2
OASIS PortalPROKR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPROKR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPROKR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PROKR2
DgiDB (Drug Gene Interaction Database)PROKR2
DoCM (Curated mutations)PROKR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PROKR2 (select a term)
intoGenPROKR2
Cancer3DPROKR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM244200    607123   
Orphanet2825    3249    8668   
MedgenPROKR2
Genetic Testing Registry PROKR2
NextProtQ8NFJ6 [Medical]
TSGene128674
GENETestsPROKR2
Target ValidationPROKR2
Huge Navigator PROKR2 [HugePedia]
snp3D : Map Gene to Disease128674
BioCentury BCIQPROKR2
ClinGenPROKR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD128674
Chemical/Pharm GKB GenePA30014
Clinical trialPROKR2
Miscellaneous
canSAR (ICR)PROKR2 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePROKR2
EVEXPROKR2
GoPubMedPROKR2
iHOPPROKR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:51:13 CEST 2017

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