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PROL1 (proline rich, lacrimal 1)

Identity

Other aliasBPLP
PRL1
opiorphin
HGNC (Hugo) PROL1
LocusID (NCBI) 58503
Atlas_Id 72241
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 71263599 and ends at 71275914 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CD86 (3q13.33) / PROL1 (4q13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PROL1   17279
Cards
Entrez_Gene (NCBI)PROL1  58503  proline rich, lacrimal 1
AliasesBPLP; PRL1; opiorphin
GeneCards (Weizmann)PROL1
Ensembl hg19 (Hinxton)ENSG00000171199 [Gene_View]  chr4:71263599-71275914 [Contig_View]  PROL1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000171199 [Gene_View]  chr4:71263599-71275914 [Contig_View]  PROL1 [Vega]
ICGC DataPortalENSG00000171199
TCGA cBioPortalPROL1
AceView (NCBI)PROL1
Genatlas (Paris)PROL1
WikiGenes58503
SOURCE (Princeton)PROL1
Genetics Home Reference (NIH)PROL1
Genomic and cartography
GoldenPath hg19 (UCSC)PROL1  -     chr4:71263599-71275914 +  4q13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PROL1  -     4q13.3   [Description]    (hg38-Dec_2013)
EnsemblPROL1 - 4q13.3 [CytoView hg19]  PROL1 - 4q13.3 [CytoView hg38]
Mapping of homologs : NCBIPROL1 [Mapview hg19]  PROL1 [Mapview hg38]
OMIM608936   
Gene and transcription
Genbank (Entrez)BC092438 BC141465 BC148720 CD721906 CD722615
RefSeq transcript (Entrez)NM_001302807 NM_021225
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)PROL1
Cluster EST : UnigeneHs.661425 [ NCBI ]
CGAP (NCI)Hs.661425
Alternative Splicing GalleryENSG00000171199
Gene ExpressionPROL1 [ NCBI-GEO ]   PROL1 [ EBI - ARRAY_EXPRESS ]   PROL1 [ SEEK ]   PROL1 [ MEM ]
Gene Expression Viewer (FireBrowse)PROL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)58503
GTEX Portal (Tissue expression)PROL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99935   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99935  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99935
Splice isoforms : SwissVarQ99935
PhosPhoSitePlusQ99935
Domains : Interpro (EBI)SMR_like   
Domain families : Pfam (Sanger)PROL5-SMR (PF15621)   
Domain families : Pfam (NCBI)pfam15621   
Conserved Domain (NCBI)PROL1
DMDM Disease mutations58503
Blocks (Seattle)PROL1
SuperfamilyQ99935
Human Protein AtlasENSG00000171199
Peptide AtlasQ99935
HPRD16408
IPIIPI00009682   
Protein Interaction databases
DIP (DOE-UCLA)Q99935
IntAct (EBI)Q99935
FunCoupENSG00000171199
BioGRIDPROL1
STRING (EMBL)PROL1
ZODIACPROL1
Ontologies - Pathways
QuickGOQ99935
Ontology : AmiGOretina homeostasis  endopeptidase inhibitor activity  extracellular region  extracellular space  negative regulation of endopeptidase activity  peptidase inhibitor activity  regulation of sensory perception of pain  
Ontology : EGO-EBIretina homeostasis  endopeptidase inhibitor activity  extracellular region  extracellular space  negative regulation of endopeptidase activity  peptidase inhibitor activity  regulation of sensory perception of pain  
NDEx NetworkPROL1
Atlas of Cancer Signalling NetworkPROL1
Wikipedia pathwaysPROL1
Orthology - Evolution
OrthoDB58503
GeneTree (enSembl)ENSG00000171199
Phylogenetic Trees/Animal Genes : TreeFamPROL1
HOVERGENQ99935
HOGENOMQ99935
Homologs : HomoloGenePROL1
Homology/Alignments : Family Browser (UCSC)PROL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPROL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PROL1
dbVarPROL1
ClinVarPROL1
1000_GenomesPROL1 
Exome Variant ServerPROL1
ExAC (Exome Aggregation Consortium)PROL1 (select the gene name)
Genetic variants : HAPMAP58503
Genomic Variants (DGV)PROL1 [DGVbeta]
DECIPHER (Syndromes)4:71263599-71275914  ENSG00000171199
CONAN: Copy Number AnalysisPROL1 
Mutations
ICGC Data PortalPROL1 
TCGA Data PortalPROL1 
Broad Tumor PortalPROL1
OASIS PortalPROL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPROL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPROL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PROL1
DgiDB (Drug Gene Interaction Database)PROL1
DoCM (Curated mutations)PROL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PROL1 (select a term)
intoGenPROL1
Cancer3DPROL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608936   
Orphanet
MedgenPROL1
Genetic Testing Registry PROL1
NextProtQ99935 [Medical]
TSGene58503
GENETestsPROL1
Huge Navigator PROL1 [HugePedia]
snp3D : Map Gene to Disease58503
BioCentury BCIQPROL1
ClinGenPROL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD58503
Chemical/Pharm GKB GenePA33803
Clinical trialPROL1
Miscellaneous
canSAR (ICR)PROL1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePROL1
EVEXPROL1
GoPubMedPROL1
iHOPPROL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:39:44 CET 2017

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