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PROSC (proline synthetase co-transcribed homolog (bacterial))

Identity

Alias_namesproline synthetase co-transcribed (bacterial homolog)
Other alias-
HGNC (Hugo) PROSC
LocusID (NCBI) 11212
Atlas_Id 72243
Location 8p11.23  [Link to chromosome band 8p11]
Location_base_pair Starts at 37620101 and ends at 37637286 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PROSC (8p11.23) / OSTM1 (6q21)PROSC (8p11.23) / PROSC (8p11.23)PROSC (8p11.23) / SET (9q34.11)
PROSC (8p11.23) / WDR82 (3p21.2)PROSC (8p11.23) / WHSC1L1 (8p11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PROSC   9457
Cards
Entrez_Gene (NCBI)PROSC  11212  proline synthetase co-transcribed homolog (bacterial)
Aliases
GeneCards (Weizmann)PROSC
Ensembl hg19 (Hinxton)ENSG00000147471 [Gene_View]  chr8:37620101-37637286 [Contig_View]  PROSC [Vega]
Ensembl hg38 (Hinxton)ENSG00000147471 [Gene_View]  chr8:37620101-37637286 [Contig_View]  PROSC [Vega]
ICGC DataPortalENSG00000147471
TCGA cBioPortalPROSC
AceView (NCBI)PROSC
Genatlas (Paris)PROSC
WikiGenes11212
SOURCE (Princeton)PROSC
Genetics Home Reference (NIH)PROSC
Genomic and cartography
GoldenPath hg19 (UCSC)PROSC  -     chr8:37620101-37637286 +  8p11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PROSC  -     8p11.23   [Description]    (hg38-Dec_2013)
EnsemblPROSC - 8p11.23 [CytoView hg19]  PROSC - 8p11.23 [CytoView hg38]
Mapping of homologs : NCBIPROSC [Mapview hg19]  PROSC [Mapview hg38]
OMIM604436   
Gene and transcription
Genbank (Entrez)AI355650 AK021923 AK291135 AL136616 AW028116
RefSeq transcript (Entrez)NM_007198
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_167187 NW_004929337
Consensus coding sequences : CCDS (NCBI)PROSC
Cluster EST : UnigeneHs.608177 [ NCBI ]
CGAP (NCI)Hs.608177
Alternative Splicing GalleryENSG00000147471
Gene ExpressionPROSC [ NCBI-GEO ]   PROSC [ EBI - ARRAY_EXPRESS ]   PROSC [ SEEK ]   PROSC [ MEM ]
Gene Expression Viewer (FireBrowse)PROSC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11212
GTEX Portal (Tissue expression)PROSC
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94903   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94903  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94903
Splice isoforms : SwissVarO94903
PhosPhoSitePlusO94903
Domaine pattern : Prosite (Expaxy)UPF0001 (PS01211)   
Domains : Interpro (EBI)Ala_racemase_N    PLP-binding_barrel    UPF0001   
Domain families : Pfam (Sanger)Ala_racemase_N (PF01168)   
Domain families : Pfam (NCBI)pfam01168   
Conserved Domain (NCBI)PROSC
DMDM Disease mutations11212
Blocks (Seattle)PROSC
SuperfamilyO94903
Human Protein AtlasENSG00000147471
Peptide AtlasO94903
HPRD16060
IPIIPI00902466   IPI00016346   IPI00983735   IPI00983028   IPI00985466   IPI00984829   IPI00981682   
Protein Interaction databases
DIP (DOE-UCLA)O94903
IntAct (EBI)O94903
FunCoupENSG00000147471
BioGRIDPROSC
STRING (EMBL)PROSC
ZODIACPROSC
Ontologies - Pathways
QuickGOO94903
Ontology : AmiGOintracellular  cytoplasm  mitochondrion  biological_process  pyridoxal phosphate binding  extracellular exosome  
Ontology : EGO-EBIintracellular  cytoplasm  mitochondrion  biological_process  pyridoxal phosphate binding  extracellular exosome  
NDEx NetworkPROSC
Atlas of Cancer Signalling NetworkPROSC
Wikipedia pathwaysPROSC
Orthology - Evolution
OrthoDB11212
GeneTree (enSembl)ENSG00000147471
Phylogenetic Trees/Animal Genes : TreeFamPROSC
HOVERGENO94903
HOGENOMO94903
Homologs : HomoloGenePROSC
Homology/Alignments : Family Browser (UCSC)PROSC
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPROSC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PROSC
dbVarPROSC
ClinVarPROSC
1000_GenomesPROSC 
Exome Variant ServerPROSC
ExAC (Exome Aggregation Consortium)PROSC (select the gene name)
Genetic variants : HAPMAP11212
Genomic Variants (DGV)PROSC [DGVbeta]
DECIPHER (Syndromes)8:37620101-37637286  ENSG00000147471
CONAN: Copy Number AnalysisPROSC 
Mutations
ICGC Data PortalPROSC 
TCGA Data PortalPROSC 
Broad Tumor PortalPROSC
OASIS PortalPROSC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPROSC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPROSC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch PROSC
DgiDB (Drug Gene Interaction Database)PROSC
DoCM (Curated mutations)PROSC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PROSC (select a term)
intoGenPROSC
Cancer3DPROSC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604436   
Orphanet
MedgenPROSC
Genetic Testing Registry PROSC
NextProtO94903 [Medical]
TSGene11212
GENETestsPROSC
Huge Navigator PROSC [HugePedia]
snp3D : Map Gene to Disease11212
BioCentury BCIQPROSC
ClinGenPROSC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11212
Chemical/Pharm GKB GenePA33810
Clinical trialPROSC
Miscellaneous
canSAR (ICR)PROSC (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePROSC
EVEXPROSC
GoPubMedPROSC
iHOPPROSC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:39:44 CET 2017

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