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PROZ (protein Z, vitamin K dependent plasma glycoprotein)

Identity

Alias_namesprotein Z
Alias_symbol (synonym)PZ
Other alias
HGNC (Hugo) PROZ
LocusID (NCBI) 8858
Atlas_Id 51035
Location 13q34  [Link to chromosome band 13q34]
Location_base_pair Starts at 113158654 and ends at 113172384 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PROZ   9460
Cards
Entrez_Gene (NCBI)PROZ  8858  protein Z, vitamin K dependent plasma glycoprotein
AliasesPZ
GeneCards (Weizmann)PROZ
Ensembl hg19 (Hinxton)ENSG00000126231 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126231 [Gene_View]  chr13:113158654-113172384 [Contig_View]  PROZ [Vega]
ICGC DataPortalENSG00000126231
TCGA cBioPortalPROZ
AceView (NCBI)PROZ
Genatlas (Paris)PROZ
WikiGenes8858
SOURCE (Princeton)PROZ
Genetics Home Reference (NIH)PROZ
Genomic and cartography
GoldenPath hg38 (UCSC)PROZ  -     chr13:113158654-113172384 +  13q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PROZ  -     13q34   [Description]    (hg19-Feb_2009)
EnsemblPROZ - 13q34 [CytoView hg19]  PROZ - 13q34 [CytoView hg38]
Mapping of homologs : NCBIPROZ [Mapview hg19]  PROZ [Mapview hg38]
OMIM176895   614024   
Gene and transcription
Genbank (Entrez)AI492996 BC074906 BC074907 M55670 M55671
RefSeq transcript (Entrez)NM_001256134 NM_003891
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PROZ
Cluster EST : UnigeneHs.1011 [ NCBI ]
CGAP (NCI)Hs.1011
Alternative Splicing GalleryENSG00000126231
Gene ExpressionPROZ [ NCBI-GEO ]   PROZ [ EBI - ARRAY_EXPRESS ]   PROZ [ SEEK ]   PROZ [ MEM ]
Gene Expression Viewer (FireBrowse)PROZ [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8858
GTEX Portal (Tissue expression)PROZ
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22891   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP22891  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP22891
Splice isoforms : SwissVarP22891
PhosPhoSitePlusP22891
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    GLA_1 (PS00011)    GLA_2 (PS50998)    TRYPSIN_DOM (PS50240)   
Domains : Interpro (EBI)Coagulation_fac_subgr_Gla_dom    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    GLA_domain    Pept_S1A_FX    Peptidase_S1_PA    Trypsin_dom   
Domain families : Pfam (Sanger)EGF (PF00008)    Gla (PF00594)    Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00008    pfam00594    pfam00089   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  GLA (SM00069)  Tryp_SPc (SM00020)  
Conserved Domain (NCBI)PROZ
DMDM Disease mutations8858
Blocks (Seattle)PROZ
PDB (SRS)3F1S    3H5C   
PDB (PDBSum)3F1S    3H5C   
PDB (IMB)3F1S    3H5C   
PDB (RSDB)3F1S    3H5C   
Structural Biology KnowledgeBase3F1S    3H5C   
SCOP (Structural Classification of Proteins)3F1S    3H5C   
CATH (Classification of proteins structures)3F1S    3H5C   
SuperfamilyP22891
Human Protein AtlasENSG00000126231
Peptide AtlasP22891
HPRD07182
IPIIPI00027843   IPI00216065   
Protein Interaction databases
DIP (DOE-UCLA)P22891
IntAct (EBI)P22891
FunCoupENSG00000126231
BioGRIDPROZ
STRING (EMBL)PROZ
ZODIACPROZ
Ontologies - Pathways
QuickGOP22891
Ontology : AmiGOserine-type endopeptidase activity  calcium ion binding  extracellular space  endoplasmic reticulum lumen  Golgi lumen  signal peptide processing  ER to Golgi vesicle-mediated transport  blood coagulation  peptidyl-glutamic acid carboxylation  negative regulation of blood coagulation  extracellular exosome  
Ontology : EGO-EBIserine-type endopeptidase activity  calcium ion binding  extracellular space  endoplasmic reticulum lumen  Golgi lumen  signal peptide processing  ER to Golgi vesicle-mediated transport  blood coagulation  peptidyl-glutamic acid carboxylation  negative regulation of blood coagulation  extracellular exosome  
NDEx NetworkPROZ
Atlas of Cancer Signalling NetworkPROZ
Wikipedia pathwaysPROZ
Orthology - Evolution
OrthoDB8858
GeneTree (enSembl)ENSG00000126231
Phylogenetic Trees/Animal Genes : TreeFamPROZ
HOVERGENP22891
HOGENOMP22891
Homologs : HomoloGenePROZ
Homology/Alignments : Family Browser (UCSC)PROZ
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPROZ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PROZ
dbVarPROZ
ClinVarPROZ
1000_GenomesPROZ 
Exome Variant ServerPROZ
ExAC (Exome Aggregation Consortium)PROZ (select the gene name)
Genetic variants : HAPMAP8858
Genomic Variants (DGV)PROZ [DGVbeta]
DECIPHERPROZ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPROZ 
Mutations
ICGC Data PortalPROZ 
TCGA Data PortalPROZ 
Broad Tumor PortalPROZ
OASIS PortalPROZ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPROZ  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPROZ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PROZ
DgiDB (Drug Gene Interaction Database)PROZ
DoCM (Curated mutations)PROZ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PROZ (select a term)
intoGenPROZ
Cancer3DPROZ(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176895    614024   
Orphanet21909   
MedgenPROZ
Genetic Testing Registry PROZ
NextProtP22891 [Medical]
TSGene8858
GENETestsPROZ
Target ValidationPROZ
Huge Navigator PROZ [HugePedia]
snp3D : Map Gene to Disease8858
BioCentury BCIQPROZ
ClinGenPROZ
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8858
Chemical/Pharm GKB GenePA33813
Clinical trialPROZ
Miscellaneous
canSAR (ICR)PROZ (select the gene name)
Probes
Litterature
PubMed87 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePROZ
EVEXPROZ
GoPubMedPROZ
iHOPPROZ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:26:40 CEST 2017

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