PRR11 (proline rich 11)

2013-11-01  

Identity

HGNC
LOCATION
17q22
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 55771
MIM: 615920
HGNC: 25619
Ensembl: ENSG00000068489

Variants:

dbSNP: 55771
ClinVar: 55771
TCGA: ENSG00000068489
COSMIC: PRR11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000068489ENST00000262293Q96HE9
ENSG00000068489ENST00000262293D2SNZ4
ENSG00000068489ENST00000577457J3QRV0
ENSG00000068489ENST00000578542Q96HE9
ENSG00000068489ENST00000578542D2SNZ4
ENSG00000068489ENST00000578777J3QR53
ENSG00000068489ENST00000580177Q96HE9
ENSG00000068489ENST00000580177D2SNZ4
ENSG00000068489ENST00000582004J3QQS2
ENSG00000068489ENST00000582995J3QKY4
ENSG00000068489ENST00000614081Q96HE9
ENSG00000068489ENST00000614081D2SNZ4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
232464892013PRR11 is a novel gene implicated in cell cycle progression and lung cancer.25
259713322015The prognostic potential and oncogenic effects of PRR11 expression in hilar cholangiocarcinoma.21
261629862015The gene pair PRR11 and SKA2 shares a NF-Y-regulated bidirectional promoter and contributes to lung cancer development.20
176729182007Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.17
285747242017miR-144-3p Induces Cell Cycle Arrest and Apoptosis in Pancreatic Cancer Cells by Targeting Proline-Rich Protein 11 Expression via the Mitogen-Activated Protein Kinase Signaling Pathway.14
256669442015PRR11 regulates late-S to G2/M phase progression and induces premature chromatin condensation (PCC).12
262522272015PRR11 Is a Prognostic Marker and Potential Oncogene in Patients with Gastric Cancer.10
293934952018miR-195 inhibits cell proliferation and angiogenesis in human prostate cancer by downregulating PRR11 expression.10
305514402019Knockdown of lncRNA DLX6-AS1 inhibits cell proliferation, migration and invasion while promotes apoptosis by downregulating PRR11 expression and upregulating miR-144 in non-small cell lung cancer.6
282570422017The PRR11-SKA2 Bidirectional Transcription Unit Is Negatively Regulated by p53 through NF-Y in Lung Cancer Cells.5

Citation

Dessen P

PRR11 (proline rich 11)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53546/prr11